Grant Number:	5R00CA260718-04 Interpret this number
Primary Investigator:	Patterson, Joanne
Organization:	Ohio State University
Project Title:	Testing the Effect of Anti-Tobacco Message Framing on Polytobacco Use in Lesbian, Gay, Bisexual, and Transgender Young Adults
Fiscal Year:	2024

PROJECT SUMMARY Polytobacco use, defined as concurrent use of more than one tobacco product including electronic nicotine delivery systems (ENDS), is rising and high in lesbian, gay, bisexual, and transgender (LGBT) young adults (YA). Between 22-40% of LGBT YA (vs 12-21% of non-LGBT YA) report past 30-day polytobacco use, and LGBT YA are less likely to perceive tobacco use as harmful. Low risk perceptions may reinforce tobacco use and widen existing disparities. The Food and Drug Administration (FDA) Center for Tobacco Products (CTP) is mandated educate the public about tobacco product risks, yet no evidence describes how to effectively frame anti- polytobacco risk communications. The proposed training objectives are for the applicant to develop advanced skills in health communication science; bio-behavioral methods, including psychophysiological measurement; and randomized controlled trials. These skills will be used to determine effective communication of polytobacco use risks to at-risk LGBT YA. This proposal directly supports the FDA’s mandate to educate the public by addressing the research priority area of Communications. While studies indicate that antitobacco communications can successfully increase public knowledge about tobacco use risks, there are limitations to the extant literature, as follows: (1) While strategies for effective risk communication are well-established, less is known about how to frame behavioral choices (e.g., total tobacco cessation vs switching to ENDS) to increase tobacco risk perceptions and intentions to quit in polytobacco users. (2) Antitobacco campaigns often leverage cultural targeting, a broadly supported but costly communications strategy, to increase at-risk population engagement. No studies have experimentally tested the effectiveness of LGBT culturally targeted vs non- targeted anti-tobacco messages. (3) Mobile multimedia messaging has been used to disseminate smoking cessation communications and may be feasible for distributing anti-polytobacco messages to LGBT YA, but this has not been investigated. Using formative and summative evaluation, the applicant will address these gaps with three Specific Aims: (1) Identify absolute and relative risk anti-polytobacco messages that effectively communicate polytobacco risks to YA; (2) Determine the effects of cultural targeting on LGBT YA polytobacco users’ attention to anti-polytobacco messages and perceived effectiveness; (3b) Assess the feasibility of delivering MMS anti-polytobacco messages developed in Aims 1 and 2 to LGBT YA via texting; and (3b) Estimate effect sizes of exposure to anti-polytobacco messages on risk perceptions and tobacco use over time. These aims support the National Cancer Institute’s (NCI) tobacco control research priority to reduce tobacco disparities by determining effective antitobacco message framing and cultural targeting to increase polytobacco risk perceptions and reduce tobacco use in an at-risk population, LGBT YA. Findings will provide public health officials, NCI, and the FDA CTP critical information about messages and digital media that may be leveraged in national health communications to reduce poly-tobacco use in at-risk populations.




Minority stressors and tobacco use among a US sample of sexual and gender minority young adults.
Authors: Figueroa W. , Jankowski E. , Curran H. , Ennis A.C. , Poteat T. , Morgan E. , Klein E. , Reczek R. , Patterson J.G. .
Source: Drug And Alcohol Dependence, 2024-08-01 00:00:00.0; 261, p. 111356.
EPub date: 2024-06-06 00:00:00.0.
PMID: 38889573
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Resonating with Pride: Considerations for Tailoring Tobacco Interventions for LGBTQ+ Communities.
Authors: Patterson J.G. , McQuoid J. , Heffner J.L. , Ye Q. , Ennis A.C. , Ganz O. , Tan A.S.L. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2024-04-18 00:00:00.0; , .
EPub date: 2024-04-18 00:00:00.0.
PMID: 38632891
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Absolute and relative e-cigarette harm perceptions among young adult lesbian and bisexual women and nonbinary people assigned female at birth.
Authors: Patterson J.G. , Keller-Hamilton B. , Wedel A. , Vázquez-Otero C. , Liu J. , Lee D. , Stevens E.M. , Wagener T.L. .
Source: Addictive Behaviors, 2023 Nov; 146, p. 107788.
EPub date: 2023-06-30 00:00:00.0.
PMID: 37429104
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The Effects of Oral Nicotine Pouch Packaging Features on Adult Tobacco Users' and Non-Users' Product Perceptions.
Authors: Mays D. , Long L. , Alalwan M.A. , Wagener T.L. , Shang C. , Roberts M.E. , Patterson J.G. , Keller-Hamilton B. .
Source: International Journal Of Environmental Research And Public Health, 2023-02-15 00:00:00.0; 20(4), .
EPub date: 2023-02-15 00:00:00.0.
PMID: 36834078
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Associations of Perceived Stress and Social Support on Health Behavior Changes in Sexual Minoritized Women During the COVID-19 Pandemic.
Authors: Lee D.N. , Stevens E.M. , Patterson J.G. , Wedel A.V. , Wagener T.L. , Keller-Hamilton B. .
Source: Women's Health Reports (new Rochelle, N.y.), 2023; 4(1), p. 182-190.
EPub date: 2023-04-17 00:00:00.0.
PMID: 37096125
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E-Cigarette Use among Sexual Minoritized Women and Nonbinary People Assigned Female at Birth: Assessing the Roles of Discrimination, Perceived Stress, and Social Support.
Authors: Wedel A.V. , Patterson J.G. , Lee D.N. , Stevens E.M. , Wagener T.L. , Keller-Hamilton B. .
Source: Substance Use & Misuse, 2023; 58(9), p. 1102-1109.
EPub date: 2023-05-18 00:00:00.0.
PMID: 37199173
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Sexual orientation and gender identity differences in perceptions and product appeal in response to e-cigarette advertising.
Authors: Liu J. , Patterson J.G. , Keller-Hamilton B. , Lee D.N. , Chrzan K.R. , Stevens E.M. .
Source: Tobacco Induced Diseases, 2023; 21, p. 111.
EPub date: 2023-09-01 00:00:00.0.
PMID: 37664443
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How Age and E-cigarette Use Status Interact to Influence E-cigarette Ad Perceptions.
Authors: Liu J. , Keller-Hamilton B. , Patterson J.G. , Lee D.N. , Wedel A.V. , Vázquez-Otero C. , Stevens E.M. .
Source: Substance Use & Misuse, 2022-12-13 00:00:00.0; , p. 1-8.
EPub date: 2022-12-13 00:00:00.0.
PMID: 36510786
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Associations between perceived source credibility, e-cigarettes, and e-cigarette ad perceptions.
Authors: Lee D.N. , Liu J. , Keller-Hamilton B. , Patterson J.G. , Wedel A.V. , Vázquez-Otero C. , Stevens E.M. .
Source: Preventive Medicine Reports, 2022 Aug; 28, p. 101862.
EPub date: 2022-06-13 00:00:00.0.
PMID: 35733610
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Correction to: A cluster randomized controlled trial for a multi-level, clinic-based smoking cessation program with women in Appalachian communities: study protocol for the "Break Free" program.
Authors: Patterson J.G. , Borger T.N. , Burris J.L. , Conaway M. , Klesges R. , Ashcraft A. , Hauser L. , Clark C. , Wright L. , Cooper S. , et al. .
Source: Addiction Science & Clinical Practice, 2022-04-01 00:00:00.0; 17(1), p. 21.
EPub date: 2022-04-01 00:00:00.0.
PMID: 35361240
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A cluster randomized controlled trial for a multi-level, clinic-based smoking cessation program with women in Appalachian communities: study protocol for the "Break Free" program.
Authors: Patterson J.G. , Borger T.N. , Burris J.L. , Conaway M. , Klesges R. , Ashcraft A. , Hauser L. , Clark C. , Wright L. , Cooper S. , et al. .
Source: Addiction Science & Clinical Practice, 2022-02-14 00:00:00.0; 17(1), p. 11.
EPub date: 2022-02-14 00:00:00.0.
PMID: 35164857
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Visual attention to blu's parody warnings and the FDA's warning on e-cigarette advertisements.
Authors: Keller-Hamilton B. , Fioritto M. , Klein E.G. , Brinkman M.C. , Pennell M.L. , Nini P. , Patterson J.G. , Ferketich A.K. .
Source: Addictive Behaviors, 2022 Feb; 125, p. 107169.
EPub date: 2021-10-30 00:00:00.0.
PMID: 34768058
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Associations of race and ethnicity with tobacco messaging exposures and tobacco use among bisexual and pansexual women.
Authors: Keller-Hamilton B. , Stevens E.M. , Wedel A.V. , LaPolt D.T. , Miranda A. , Wagener T.L. , Patterson J.G. .
Source: Preventive Medicine Reports, 2022 Feb; 25, p. 101657.
EPub date: 2021-12-09 00:00:00.0.
PMID: 34976704
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Responses to e-cigarette health messages among young adult sexual minoritized women and nonbinary people assigned female at birth: Assessing the influence of message theme and format.
Authors: Patterson J.G. , Keller-Hamilton B. , Wedel A.V. , Wagener T.L. , Stevens E.M. .
Source: Drug And Alcohol Dependence, 2022-02-01 00:00:00.0; 231, p. 109249.
EPub date: 2021-12-31 00:00:00.0.
PMID: 35030509
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Minoritized Sexual Identity and Perceived Effectiveness of Instagram Public Health Messaging about E-cigarettes.
Authors: Lee D.N. , Stevens E.M. , Keller-Hamilton B. , Wedel A.V. , Wagener T.L. , Patterson J.G. .
Source: Journal Of Health Communication, 2022-02-01 00:00:00.0; 27(2), p. 115-124.
EPub date: 2022-04-06 00:00:00.0.
PMID: 35382702
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Psychosocial factors influencing smoking relapse among youth experiencing homelessness: A qualitative study.
Authors: Patterson J.G. , Macisco J.M. , Glasser A.M. , Wermert A. , Nemeth J.M. .
Source: Plos One, 2022; 17(7), p. e0270665.
EPub date: 2022-07-26 00:00:00.0.
PMID: 35881608
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A Call for Regulatory Clarity: "Switch" and "Quit Smoking" Marketing among Online Disposable E-Cigarette Sellers.
Authors: Miranda A.R. , Patterson J.G. , LaPolt D. , Rumano R.P. , Reynoso A.M. , Berman M.L. , Keller-Hamilton B.L. , Roberts M.E. , Ferketich A.K. , Zettler P.J. .
Source: Harvard Public Health Review (cambridge, Mass.), 2022; 61, .
EPub date: 2022-09-07 00:00:00.0.
PMID: 37284601
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