Skip to main content
Grant Details

Grant Number: 5R50CA251966-04 Interpret this number
Primary Investigator: Carroll, Nikki
Organization: Kaiser Foundation Research Institute
Project Title: Natural History of Lung Cancer Diagnosed Within and Across Diverse Health Systems Implementing Lung Cancer Screening
Fiscal Year: 2023


Project Summary/Abstract The goal of this application is to support Nikki Carroll, MS, as a Research Specialist and Biostatistician at Kaiser Permanente Colorado Institute for Health Research. She supports the Cancer and Genomics Research Core under the direction of Debra Ritzwoller, PhD. The core of Ms. Carroll’s productive and successful career as a Research Specialist and Biostatistician is in cancer related treatment patterns and outcomes. This Research Specialist award would allow 5 years of funding to maintain protected time for Ms. Carroll to work exclusively on supporting and leading cancer research aimed at generating real-world evidence on cancer care that occurs outside of clinical trials. In particular, she will study the treatment patterns and risk of recurrence among those with screen detected lung cancer compared to lung cancers diagnosed outside of screening. These results could impact prognostic estimates, treatment choices, and future trials to develop tailored treatment and surveillance regimens for early-stage, screen-detected lung cancer patients and set the foundation for future studies of the natural history of lung cancer screening in community settings. Results will be broadly disseminated through local and national meetings as well as peer-reviewed journal manuscripts.


Individuals Eligible for Lung Cancer Screening Less Likely to Receive Screening When Enrolled in Health Plans With Deductibles.
Authors: Wain K. , Carroll N.M. , Honda S. , Oshiro C. , Ritzwoller D.P. .
Source: Medical care, 2023-10-01; 61(10), p. 665-673.
EPub date: 2023-08-10.
PMID: 37582296
Related Citations

Development of an Electronic Health Record-Based Algorithm for Predicting Lung Cancer Screening Eligibility in the Population-Based Research to Optimize the Screening Process Lung Research Consortium.
Authors: Burnett-Hartman A.N. , Powers J.D. , Hixon B.P. , Carroll N.M. , Frankland T.B. , Honda S.A. , Saia C. , Rendle K.A. , Greenlee R.T. , Neslund-Dudas C. , et al. .
Source: JCO clinical cancer informatics, 2023 Sep; 7, p. e2300063.
PMID: 37910824
Related Citations

Smoking status and the association between patient-level factors and survival among lung cancer patients.
Authors: Carroll N.M. , Burnett-Hartman A.N. , Rendle K.A. , Neslund-Dudas C.M. , Greenlee R.T. , Honda S.A. , Vachani A. , Ritzwoller D.P. .
Source: Journal of the National Cancer Institute, 2023-08-08; 115(8), p. 937-948.
PMID: 37228018
Related Citations

Percentage Up to Date With Chest Computed Tomography Among Those Eligible for Lung Cancer Screening.
Authors: Burnett-Hartman A.N. , Carroll N.M. , Croswell J.M. , Greenlee R.T. , Honda S.A. , Neslund-Dudas C.M. , Kim R.Y. , Rendle K.A. , Vachani A. , Ritzwoller D.P. .
Source: American journal of preventive medicine, 2023 Jul; 65(1), p. 126-130.
EPub date: 2023-01-25.
PMID: 36707314
Related Citations

Uptake of novel systemic therapy: Real world patterns among adults with advanced non-small cell lung cancer.
Authors: Carroll N.M. , Eisenstein J. , Burnett-Hartman A.N. , Greenlee R.T. , Honda S.A. , Neslund-Dudas C.M. , Rendle K.A. , Vachani A. , Ritzwoller D.P. .
Source: Cancer treatment and research communications, 2023; 36, p. 100730.
EPub date: 2023-06-14.
PMID: 37352588
Related Citations

Community-based Lung Cancer Screening Results in Relation to Patient and Radiologist Characteristics: The PROSPR Consortium.
Authors: Burnett-Hartman A.N. , Carroll N.M. , Honda S.A. , Joyce C. , Mitra N. , Neslund-Dudas C. , Olaiya O. , Rendle K.A. , Schnall M.D. , Vachani A. , et al. .
Source: Annals of the American Thoracic Society, 2022 Mar; 19(3), p. 433-441.
PMID: 34543590
Related Citations

Evaluation of Population-Level Changes Associated With the 2021 US Preventive Services Task Force Lung Cancer Screening Recommendations in Community-Based Health Care Systems.
Authors: Ritzwoller D.P. , Meza R. , Carroll N.M. , Blum-Barnett E. , Burnett-Hartman A.N. , Greenlee R.T. , Honda S.A. , Neslund-Dudas C. , Rendle K.A. , Vachani A. .
Source: JAMA network open, 2021-10-01; 4(10), p. e2128176.
EPub date: 2021-10-01.
PMID: 34636916
Related Citations

Back to Top