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Grant Details

Grant Number: 5P50CA244289-04 Interpret this number
Primary Investigator: Devoe, Jennifer
Organization: Oregon Health & Science University
Project Title: Building Research in Implementation and Dissemination to Close Gaps and Achieve Equity in Cancer Control (Bridge-C2) Center
Fiscal Year: 2022


OVERALL PROJECT SUMMARY The Building Research in Implementation and Dissemination to close Gaps and achieve Equity in Cancer Control (BRIDGE-C2) Center will take on the grand challenge of advancing implementation science to improve cancer screening and prevention in underserved populations. This work is urgently needed because cancer screening and prevention disparities exist with regard to delivery of evidence-based interventions (EBIs). Effective strategies to improve implementation of EBIs in primary care community health centers (CHCs) that can eliminate these disparities are not known or poorly understood. Implementation science can contribute new knowledge that will transform CHCs' ability to serve the nation's most vulnerable populations. The BRIDGE-C2 Center will: 1) create a sustainable infrastructure for developing, conducting, and continuously evaluating implementation strategies that enhance primary care's ability to equitably deliver evidence-based cancer screening and prevention interventions to all people, emphasizing closing care gaps for vulnerable populations; 2) build capacity and training opportunities, and engage a multi-disciplinary team of implementation science and methods experts, to facilitate the development of innovative approaches relevant to our grand challenge; and 3) identify strategies to improve implementation of cancer screening and prevention EBIs in primary care, and conduct research / develop pragmatic methods to tailor, enhance, and support the adoption and sustainability of these strategies. We will build on the strong established partnerships between researchers at Oregon Health & Science (OHSU) primary care, the OHSU Knight Cancer Institute, and the OCHIN Implementation Laboratory (a well-established national network of >500 CHCs that share an electronic health record through the OCHIN Practice-Based Research Network). The BRIDGE-C2 Center will conduct pilot studies that develop and test strategies to improve implementation of EBIs, rapidly scale up successful pilots to conduct large scale pragmatic trials, and widely disseminate effective innovations to primary care practices caring for underserved populations. Woven throughout these activities will be the Center's focus on mentoring and training early career implementation scientists and leveraging collaborations to increase implementation science capacity. The Center's Administrative Core will serve as the nucleus that bridges the Research Program and Implementation Laboratory, providing support for research activities, leadership, governance, investigator development, dissemination, evaluation, and a connection to the national ISCCC network. Our first two research pilots aim to improve cervical cancer screening and follow-up care and tobacco cessation. Our first two methods pilots will create novel capabilities to predict needed implementation support based on provider and practice characteristics. We will spread our discoveries and create mechanisms for widely disseminating our findings and innovations to scientific, professional, and community networks to increase implementation of cancer screening and prevention EBIs and decrease health disparities.


Preventive service utilization among low-income cancer survivors.
Authors: Blackburn B.E. , Marino M. , Schmidt T. , Heintzman J. , Hatch B. , DeVoe J. , Moreno L. , Huguet N. .
Source: Journal of cancer survivorship : research and practice, 2022 Oct; 16(5), p. 1047-1054.
EPub date: 2021-08-19.
PMID: 34409521
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Collaboration networks of the implementation science centers for cancer control: a social network analysis.
Authors: Jacob R.R. , Korn A.R. , Huang G.C. , Easterling D. , Gundersen D.A. , Ramanadhan S. , Vu T. , Angier H. , Brownson R.C. , Haire-Joshu D. , et al. .
Source: Implementation science communications, 2022-04-13; 3(1), p. 41.
EPub date: 2022-04-13.
PMID: 35418309
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Affordable Care Act Medicaid expansion and access to primary-care based smoking cessation assistance among cancer survivors: an observational cohort study.
Authors: Bailey S.R. , Voss R. , Angier H. , Huguet N. , Marino M. , Valenzuela S.H. , Chung-Bridges K. , DeVoe J.E. .
Source: BMC health services research, 2022-04-12; 22(1), p. 488.
EPub date: 2022-04-12.
PMID: 35414079
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Community Health Centers' Performance in Cancer Screening and Prevention.
Authors: Huguet N. , Hodes T. , Holderness H. , Bailey S.R. , DeVoe J.E. , Marino M. .
Source: American journal of preventive medicine, 2022 Feb; 62(2), p. e97-e106.
EPub date: 2021-10-16.
PMID: 34663549
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Effectiveness of an insurance enrollment support tool on insurance rates and cancer prevention in community health centers: a quasi-experimental study.
Authors: Huguet N. , Valenzuela S. , Marino M. , Moreno L. , Hatch B. , Baron A. , Cohen D.J. , DeVoe J.E. .
Source: BMC health services research, 2021-10-30; 21(1), p. 1186.
EPub date: 2021-10-30.
PMID: 34717616
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Assessing Cancer History Accuracy in Primary Care Electronic Health Records Through Cancer Registry Linkage.
Authors: Hoopes M. , Voss R. , Angier H. , Marino M. , Schmidt T. , DeVoe J.E. , Soule J. , Huguet N. .
Source: Journal of the National Cancer Institute, 2021-07-01; 113(7), p. 924-932.
PMID: 33377908
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Strengthening methods for tracking adaptations and modifications to implementation strategies.
Authors: Haley A.D. , Powell B.J. , Walsh-Bailey C. , Krancari M. , Gruß I. , Shea C.M. , Bunce A. , Marino M. , Frerichs L. , Lich K.H. , et al. .
Source: BMC medical research methodology, 2021-06-26; 21(1), p. 133.
EPub date: 2021-06-26.
PMID: 34174834
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Prevalence of Pre-existing Conditions Among Community Health Center Patients With COVID-19: Implications for the Patient Protection and Affordable Care Act.
Authors: Huguet N. , Schmidt T. , Larson A. , O'Malley J. , Hoopes M. , Angier H. , Marino M. , DeVoe J. .
Source: Journal of the American Board of Family Medicine : JABFM, 2021 Feb; 34(Suppl), p. S247-S249.
PMID: 33622847
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SARS-CoV-2 Testing and Changes in Primary Care Services in a Multistate Network of Community Health Centers During the COVID-19 Pandemic.
Authors: Heintzman J. , O'Malley J. , Marino M. , Todd J.V. , Stange K.C. , Huguet N. , Gold R. .
Source: JAMA, 2020-10-13; 324(14), p. 1459-1462.
PMID: 32870237
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A Practice-Based Research Network (PBRN) Roadmap for Evaluating COVID-19 in Community Health Centers: A Report From the OCHIN PBRN.
Authors: DeVoe J.E. , Likumahuwa-Ackman S.M. , Angier H.E. , Huguet N. , Cohen D.J. , Flocke S.A. , Marino M. , Gold R. .
Source: Journal of the American Board of Family Medicine : JABFM, 2020 Sep-Oct; 33(5), p. 774-778.
PMID: 32989072
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The Affordable Care Act improved health insurance coverage and cardiovascular-related screening rates for cancer survivors seen in community health centers.
Authors: Angier H.E. , Marino M. , Springer R.J. , Schmidt T.D. , Huguet N. , DeVoe J.E. .
Source: Cancer, 2020-07-15; 126(14), p. 3303-3311.
EPub date: 2020-04-15.
PMID: 32294251
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