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Grant Details

Grant Number: 5R50CA251966-03 Interpret this number
Primary Investigator: Carroll, Nikki
Organization: Kaiser Foundation Research Institute
Project Title: Natural History of Lung Cancer Diagnosed Within and Across Diverse Health Systems Implementing Lung Cancer Screening
Fiscal Year: 2022


Project Summary/Abstract The goal of this application is to support Nikki Carroll, MS, as a Research Specialist and Biostatistician at Kaiser Permanente Colorado Institute for Health Research. She supports the Cancer and Genomics Research Core under the direction of Debra Ritzwoller, PhD. The core of Ms. Carroll’s productive and successful career as a Research Specialist and Biostatistician is in cancer related treatment patterns and outcomes. This Research Specialist award would allow 5 years of funding to maintain protected time for Ms. Carroll to work exclusively on supporting and leading cancer research aimed at generating real-world evidence on cancer care that occurs outside of clinical trials. In particular, she will study the treatment patterns and risk of recurrence among those with screen detected lung cancer compared to lung cancers diagnosed outside of screening. These results could impact prognostic estimates, treatment choices, and future trials to develop tailored treatment and surveillance regimens for early-stage, screen-detected lung cancer patients and set the foundation for future studies of the natural history of lung cancer screening in community settings. Results will be broadly disseminated through local and national meetings as well as peer-reviewed journal manuscripts.


Community-based Lung Cancer Screening Results in Relation to Patient and Radiologist Characteristics: The PROSPR Consortium.
Authors: Burnett-Hartman A.N. , Carroll N.M. , Honda S.A. , Joyce C. , Mitra N. , Neslund-Dudas C. , Olaiya O. , Rendle K.A. , Schnall M.D. , Vachani A. , et al. .
Source: Annals of the American Thoracic Society, 2022 Mar; 19(3), p. 433-441.
PMID: 34543590
Related Citations

Evaluation of Population-Level Changes Associated With the 2021 US Preventive Services Task Force Lung Cancer Screening Recommendations in Community-Based Health Care Systems.
Authors: Ritzwoller D.P. , Meza R. , Carroll N.M. , Blum-Barnett E. , Burnett-Hartman A.N. , Greenlee R.T. , Honda S.A. , Neslund-Dudas C. , Rendle K.A. , Vachani A. .
Source: JAMA network open, 2021-10-01; 4(10), p. e2128176.
EPub date: 2021-10-01.
PMID: 34636916
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