Grant Details
Grant Number: |
5R01CA239308-03 Interpret this number |
Primary Investigator: |
Popova, Lyudmila |
Organization: |
Georgia State University |
Project Title: |
Communicating About Nicotine and Differential Risks of Tobacco Products |
Fiscal Year: |
2021 |
Abstract
ABSTRACT
The US Food and Drug Administration’s (FDA) potentially groundbreaking plan to reduce tobacco-related
death and disease by lowering nicotine in combusted cigarettes to minimally addictive levels has many
challenges. The tobacco industry and its allies argue that it would lead to a skyrocketing black market and
public and political backlash. Some caution that smokers would view reduced nicotine cigarettes as less
harmful, which would deter quitting, similar to how “light” and “mild” descriptors caused many health-conscious
smokers to continue smoking. To maximize the benefits of this potentially life-saving policy, it is necessary to
develop effective ways to communicate about nicotine in various tobacco products and about the health risks
of using products that have different levels of nicotine, such as combusted cigarettes and electronic nicotine
delivery systems (ENDS). One promising communication strategy is to combine messages about reduced
nicotine in combusted cigarettes with messages about lower risks of other nicotine-delivering products (i.e.,
“modified risk claims”). Our central hypothesis is that the two types of messages in combination have greater
positive impact than either type alone. This might be due to modified risk messages being able to mitigate
negative emotional reactions and reactance to reduced nicotine messages. Yet this communication strategy
remains virtually unexplored. Research is sorely needed to examine these two types of messages as they
present both sides of the FDA’s new comprehensive plan for nicotine and tobacco regulation. This project will
provide that research by pursuing these specific aims: (1) Develop preliminary messages about reduced
nicotine in combusted tobacco products using qualitative focus groups; (2) Quantify the relative importance of
different types of information in communications about reduced nicotine using Discrete Choice Experiment; (3)
Test the impact of messages about reduced nicotine in combusted tobacco products in the context of modified
risk statements for novel tobacco products in a randomized clinical trial with a nationally representative sample
of adult current exclusive smokers, dual users, and young adult (18-29) non-smokers. This project will use
insights from communication and decision sciences to produce data that will contribute to the science that
informs FDA regulatory actions around product review, product standards, and public education on nicotine
and the differential risks of tobacco products.
Publications
Perceptions of a reduced nicotine policy and predictors of policy support: A nationally representative U.S. survey.
Authors: Reynolds R.M.
, Trasher J.F.
, Yang B.
, Henderson K.C.
, Ashley D.L.
, Hackworth E.E.
, Ntansah C.A.
, Pei D.
, Popova L.
.
Source: Preventive Medicine, 2024 Jul; 184, p. 107952.
EPub date: 2024-04-23 00:00:00.0.
PMID: 38657684
Related Citations
Independent and combined effects of very low nicotine cigarette messages and e-cigarette messages: a randomised clinical trial.
Authors: Pei D.
, Reynolds R.M.
, Ntansah C.A.
, Hackworth E.E.
, Henderson K.C.
, Yang B.
, Duong H.T.
, Ashley D.L.
, Thrasher J.F.
, Popova L.
.
Source: Tobacco Control, 2024-04-25 00:00:00.0; , .
EPub date: 2024-04-25 00:00:00.0.
PMID: 38664002
Related Citations
Support for nicotine reduction in cigarettes: findings from the 2016 and 2020 ITC Four Country Smoking and Vaping Surveys.
Authors: Fairman R.T.
, Cho Y.J.
, Popova L.
, Cummings K.M.
, Smith T.T.
, Fong G.T.
, Gravely S.
, Borland R.
, McNeill A.
, Gartner C.E.
, et al.
.
Source: Tobacco Control, 2023-12-08 00:00:00.0; , .
EPub date: 2023-12-08 00:00:00.0.
PMID: 38071523
Related Citations
A Focus Group Study of Reactions to Messages about a Nicotine Reduction Policy Among People Who Use Little Cigars and Cigarillos.
Authors: Ntansah C.A.
, Hackworth E.E.
, Henderson K.C.
, Reynolds R.
, Yang B.
, Ashley D.L.
, Duong H.T.
, Thrasher J.F.
, Popova L.
.
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2023-08-19 00:00:00.0; , .
EPub date: 2023-08-19 00:00:00.0.
PMID: 37596965
Related Citations
Premium Cigar Festivals: A Potential Target for Marketing Restrictions.
Authors: Ozga J.E.
, Smiley S.L.
, Hart J.L.
, Popova L.
, Stanton C.A.
.
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2023-07-28 00:00:00.0; 25(Suppl_1), p. S81-S83.
PMID: 37506236
Related Citations
Effects of a Reduced Risk Claim on Adolescents' Smokeless Tobacco Perceptions and Willingness to Use.
Authors: Chaffee B.W.
, Couch E.T.
, Popova L.
, Halpern-Felsher B.
.
Source: The Journal Of Adolescent Health : Official Publication Of The Society For Adolescent Medicine, 2023-06-09 00:00:00.0; , .
EPub date: 2023-06-09 00:00:00.0.
PMID: 37294249
Related Citations
"I Crave a Blunt, I Don't Crave a Cigarillo": A Focus Group Study on Perceptions of Nicotine and Addiction among US Adults Who Currently Smoke Little Cigars or Cigarillos.
Authors: Hackworth E.E.
, Ntansah C.A.
, Henderson K.C.
, Pei D.
, Reynolds R.M.
, Duong H.T.
, Yang B.
, Ashley D.L.
, Thrasher J.F.
, Popova L.
.
Source: International Journal Of Environmental Research And Public Health, 2023-03-14 00:00:00.0; 20(6), .
EPub date: 2023-03-14 00:00:00.0.
PMID: 36981995
Related Citations
Messaging about very low nicotine cigarettes (VLNCs) to influence policy attitudes, harm perceptions and smoking motivations: a discrete choice experiment.
Authors: Reynolds R.M.
, Popova L.
, Ashley D.L.
, Henderson K.C.
, Ntansah C.A.
, Yang B.
, Hackworth E.E.
, Hardin J.
, Thrasher J.
.
Source: Tobacco Control, 2022-09-28 00:00:00.0; , .
EPub date: 2022-09-28 00:00:00.0.
PMID: 36171147
Related Citations
Perceptions of Nicotine Reduction Policy in the United States: A Qualitative Study.
Authors: Henderson K.C.
, Loud E.E.
, Duong H.T.
, Reynolds R.M.
, Yang B.
, Ntansah C.A.
, Ashley D.L.
, Thrasher J.F.
, Popova L.
.
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2022-08-06 00:00:00.0; 24(9), p. 1422-1429.
PMID: 35312014
Related Citations
Balancing Risks and Benefits of E-Cigarettes in the Real World.
Authors: Cohen J.E.
, Krishnan-Sarin S.
, Eissenberg T.
, Gould T.J.
, Berman M.L.
, Bhatnagar A.
, Barnett T.E.
, Soule E.
, Popova L.
, Tan A.S.L.
, et al.
.
Source: American Journal Of Public Health, 2022 02; 112(2), p. e1-e2.
PMID: 35080942
Related Citations
Which tobacco control policies do smokers support? Findings from the International Tobacco Control Four Country Smoking and Vaping Survey.
Authors: Smith T.T.
, Nahhas G.J.
, Borland R.
, Cho Y.J.
, Chung-Hall J.
, Fairman R.T.
, Fong G.T.
, McNeill A.
, Popova L.
, Thrasher J.F.
, et al.
.
Source: Preventive Medicine, 2021 08; 149, p. 106600.
EPub date: 2021-05-03 00:00:00.0.
PMID: 33957152
Related Citations
Addicted to smoking or addicted to nicotine?: A focus group study on perceptions of nicotine and addiction among US adult current smokers, former smokers, non-smokers, and dual users of cigarettes and e-cigarettes.
Authors: Loud E.E.
, Duong H.T.
, Henderson K.
, Reynolds R.
, Ashley D.
, Thrasher J.F.
, Popova L.
.
Source: Addiction (abingdon, England), 2021-07-06 00:00:00.0; , .
EPub date: 2021-07-06 00:00:00.0.
PMID: 34227709
Related Citations
'It brings light to what you really put into your body': a focus group study of reactions to messages about nicotine reduction in cigarettes.
Authors: Duong H.T.
, Loud E.E.
, Thrasher J.F.
, Henderson K.C.
, Ashley D.L.
, Popova L.
.
Source: Tobacco Control, 2021-04-16 00:00:00.0; , .
EPub date: 2021-04-16 00:00:00.0.
PMID: 33863835
Related Citations