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Grant Details

Grant Number: 5R01CA214530-05 Interpret this number
Primary Investigator: Brownson, Ross
Organization: Washington University
Project Title: Mis-Implementation in Cancer Prevention and Control
Fiscal Year: 2021


PROJECT SUMMARY BACKGROUND: Through application of existing knowledge, much of the cancer burden is preventable. State- level practitioners are in ideal positions to affect programs and policies related to cancer control. Mis- implementation refers to ending effective programs and policies or continuing ineffective ones. Greater attention to mis-implementation should lead to use of effective interventions and more efficient expenditure of resources, which in the long term, will lead to positive cancer outcomes. GOAL: This proposal seeks to describe the extent of cancer control mis-implementation and to identify leverage points for addressing mis-implementation in the United States. AIMS AND METHODS: This is a three-phase study that takes a comprehensive approach, leading to the elucidation of tactics for addressing mis-implementation. Phase 1: The first aim seeks to assess the extent to which mis-implementation is occurring among state cancer control programs in public health. This initial phase will involve a survey of 800 practitioners representing all states. The programs represented will span the full continuum of cancer control (from prevention to survivorship). Phase 2: Using data from Phase 1 to identify organizations in which mis-implementation is high or low, we will conduct eight comparative case studies to understand contextual differences. These case studies will highlight lessons learned about mis-implementation and identify hypothesized drivers. Phase 3: The 3rd aim seeks to build agent-based models to identify dynamic interactions between individual, organizational, and contextual (external) factors driving mis-implementation. Agent-based modeling will be used to determine the most effective potential approaches for reducing mis- implementation. We will translate and disseminate findings from Phases 1-3 to practitioners and practice- related stakeholders in order to support the reduction of mis-implementation. All study phases will rely on an Advisory Group of public health practitioners and close collaboration with key practice partners. INNOVATIONS AND IMPACT: This study is innovative and impactful because it will: 1) be the first to refine and further develop reliable and valid measures of mis-implementation of public health programs; 2) bring together a strong, transdisciplinary team with significant expertise in practice-based research; 3) use agent- based modeling to address cancer control implementation; and 4) use a participatory, evidence-based, stakeholder-driven approach that will identify key leverage points for addressing mis-implementation among state public health programs. This research is expected to result in a replicable model that can significantly impact mis-implementation in cancer control and can be applied to other health areas.


Understanding Misimplementation in U.S. State Health Departments: An Agent-Based Model.
Authors: Kasman M. , Hammond R.A. , Purcell R. , Saliba L.F. , Mazzucca-Ragan S. , Padek M. , Allen P. , Luke D.A. , Moreland-Russell S. , Erwin P.C. , et al. .
Source: American journal of preventive medicine, 2023 Apr; 64(4), p. 525-534.
EPub date: 2022-12-10.
PMID: 36509634
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Leading the way: competencies of leadership to prevent mis-implementation of public health programs.
Authors: Moreland-Russell S. , Farah Saliba L. , Rodriguez Weno E. , Smith R. , Padek M. , Brownson R.C. .
Source: Health education research, 2022-09-23; 37(5), p. 279-291.
PMID: 36069114
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The power of partnerships: state public health department multisector collaborations in major chronic disease programme areas in the United States.
Authors: Tsai E. , Allen P. , Saliba L.F. , Brownson R.C. .
Source: Health research policy and systems, 2022-07-08; 20(1), p. 80.
EPub date: 2022-07-08.
PMID: 35804420
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"It's good to feel like you're doing something": a qualitative study examining state health department employees' views on why ineffective programs continue to be implemented in the USA.
Authors: Mazzucca S. , Saliba L.F. , Smith R. , Weno E.R. , Allen P. , Padek M. , Brownson R.C. .
Source: Implementation science communications, 2022-01-15; 3(1), p. 4.
EPub date: 2022-01-15.
PMID: 35033206
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Program adaptation by health departments.
Authors: Farah Saliba L. , Allen P. , Mazzucca S.L. , Rodriguez Weno E. , Moreland-Russell S. , Padek M. , Brownson R.C. .
Source: Frontiers in public health, 2022; 10, p. 892258.
EPub date: 2022-09-12.
PMID: 36172214
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Patterns and correlates of mis-implementation in state chronic disease public health practice in the United States.
Authors: Padek M.M. , Mazzucca S. , Allen P. , Rodriguez Weno E. , Tsai E. , Luke D.A. , Brownson R.C. .
Source: BMC public health, 2021-01-28; 21(1), p. 101.
EPub date: 2021-01-28.
PMID: 33504338
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Approaches for Ending Ineffective Programs: Strategies From State Public Health Practitioners.
Authors: Rodriguez Weno E. , Allen P. , Mazzucca S. , Farah Saliba L. , Padek M. , Moreland-Russell S. , Brownson R.C. .
Source: Frontiers in public health, 2021; 9, p. 727005.
EPub date: 2021-08-20.
PMID: 34490203
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Use and Awareness of The Community Guide in State and Local Health Department Chronic Disease Programs.
Authors: Rodriguez Weno E. , Mazzucca S. , Parks R.G. , Padek M. , Allen P. , Brownson R.C. .
Source: Preventing chronic disease, 2020-10-22; 17, p. E133.
EPub date: 2020-10-22.
PMID: 33092684
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Rugged landscapes: complexity and implementation science.
Authors: Ornstein J.T. , Hammond R.A. , Padek M. , Mazzucca S. , Brownson R.C. .
Source: Implementation science : IS, 2020-09-29; 15(1), p. 85.
EPub date: 2020-09-29.
PMID: 32993756
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Going beyond the individual: how state-level characteristics relate to HPV vaccine rates in the United States.
Authors: Franco M. , Mazzucca S. , Padek M. , Brownson R.C. .
Source: BMC public health, 2019-02-28; 19(1), p. 246.
EPub date: 2019-02-28.
PMID: 30819149
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Toward optimal implementation of cancer prevention and control programs in public health: a study protocol on mis-implementation.
Authors: Padek M. , Allen P. , Erwin P.C. , Franco M. , Hammond R.A. , Heuberger B. , Kasman M. , Luke D.A. , Mazzucca S. , Moreland-Russell S. , et al. .
Source: Implementation science : IS, 2018-03-23; 13(1), p. 49.
EPub date: 2018-03-23.
PMID: 29566717
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The Association Between Evidence-Based Decision Making and Accreditation of State Health Departments.
Authors: Erwin P.C. , Padek M.M. , Allen P. , Smith R. , Brownson R.C. .
Source: Journal of public health management and practice : JPHMP, 2020 Sep/Oct; 26(5), p. 419-427.
PMID: 32732714
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