||5R01CA249883-02 Interpret this number
||University Of Texas, Austin
||Depressive Symptoms and Tobacco Use Trajectories and Transitions Across Young Adulthood
Young adults have the highest prevalence of past-year depression and current tobacco use in the United
States. Co-occurrence of depression and tobacco use is particularly problematic during young adulthood as
nicotine addiction is solidified in this developmental period, and elevated levels of depressive symptoms
promote sustained tobacco use and undermine quitting. Yet, there is limited research on young adults and
evidence for the strength and direction of associations between depressive symptoms and tobacco use is
inconclusive. Inconclusive findings indicate there may be heterogeneity in the patterns of associations between
depressive symptoms and tobacco use across subgroups of young adults. Yet, few studies examine this
heterogeneity. Further, most studies focus on cigarettes, although other products, such as electronic nicotine
delivery systems, are increasingly prevalent and the concurrent use of two or more products (i.e., poly tobacco
use) is more prevalent than single product use among young adults. Use of newly introduced vape pods, such
as JUUL, is increasingly concerning. But, the role of vape pod use in the depressive symptoms-tobacco use
association is not known. There is a critical need for longitudinal studies that identify for whom and under what
conditions depressive symptoms are associated with use of all types of tobacco, and with transitions in use,
such as from current to no tobacco use and vice versa. The primary objectives of this R01 are to determine if:
1) the role of depressive symptoms in tobacco use trajectories and transitions vary for subgroups across young
adulthood, ages 18-34 and 2) the strength and direction of associations vary. We will identify moderating
factors that capture the heterogeneity, and define for whom and under what conditions depressive symptoms
are longitudinally associated with tobacco use outcomes. We will examine sociodemographic, intrapersonal,
and contextual moderating factors, and all types of tobacco products and outcomes, including initiation,
sustained use, addiction, cessation, poly tobacco use, and transitions in use. To do so, we will use eight waves
of existing data collected in 2014-2019 from 5,482 initially 18-29 year old college students. The Specific Aims
are to: 1) Identify the role of depressive symptoms in longitudinal tobacco use trajectories and transitions, and
elucidate the temporal associations between depressive symptoms and tobacco use; 2) Examine the
moderating roles of sociodemographic, intrapersonal, and contextual factors in the longitudinal trajectories,
transitions, and temporal associations; and 3) Determine the role of vape pods, like JUUL, in the longitudinal
tobacco use trajectories, transitions, and temporal associations. The expected outcome is identification of
subgroups most vulnerable to initiating and continuing tobacco use, given elevated depressive symptoms.
Results can be used to tailor tobacco interventions and determine to whom they should be targeted.
Rising vape pod popularity disrupted declining use of electronic nicotine delivery systems among young adults in Texas, USA from 2014 to 2019.
, Marti C.N.
, Pasch K.E.
, Harrell M.B.
, Wilkinson A.V.
, Perry C.L.
Addiction (Abingdon, England), 2021-06-22; , .
Tobacco Magazine Advertising Impacts Longitudinal Changes in the Number of Tobacco Products Used by Young Adults.
, Lewis M.J.
, Marti C.N.
, Pasch K.E.
, Perry C.L.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2021 04; 68(4), p. 773-779.