||1R21CA252850-01 Interpret this number
||Medical University Of South Carolina
||Implementation of Home-Based Palliative Care in Limited Resource Settings
The extremely limited use of palliative care in low resource settings exacerbates suffering in patients with life-
limiting illnesses such as cancer. This is particularly a problem for patients living in rural areas where barriers
to care are even more pronounced. These barriers include factors such as distance from a cancer center, lack
of healthcare providers in rural communities, restrictive morphine access policies, lack of transportation and
treatment costs. For these reasons, most patients living in rural communities never receive palliative care or
even basic pain management. In recognition of the urgent need for palliative care in limited resource settings,
the World Health Organization released the Palliative Care Toolkit as a resource that community members can
use to deliver palliative care in their own communities. The toolkit provides evidence-based educational
materials to manage the physical, emotional and practical challenges of life-threatening illnesses, along with
data collection instruments to assess and manage patient needs. We will carry out a pragmatic clinical trial to
evaluate implementation of a novel Pal-Care intervention that will leverage community health workers to
facilitate the delivery of basic palliative care using the Palliative Care Toolkit. The study will be conducted at
the Tata Medical Center in Kolkata India, among their patients who reside in the 24 Parganas region outside of
Kolkata, India. With randomization at the patient level, there will be an intervention group which will receive
home-based palliative care services from a community health worker trained in palliative care and a control
group which will receive standard cancer-center based palliative care services. Two specific aims will be
evaluated within the study. Aim 1 will be to evaluate implementation of the home-based palliative care
intervention within the context of the RE-AIM Framework domains (e.g. Reach, Effectiveness, Adoption,
Implementation and Maintenance). To evaluate this aim, we will triangulate data from multiple data sources,
including pre-post surveys to evaluate the community health worker training, palliative care logs completed by
navigators while delivering care, meeting minutes and post-intervention interviews with cancer center
stakeholders (clinical team, health workers and patients/caregivers). Aim 2 will be to evaluate outcomes of this
intervention to determine its relative effects compared to a standard control group on diverse patient endpoints,
including palliative care needs, symptom burden, quality of life and experience with care.
Barriers, Facilitators and Recommended Strategies for Implementing a Home-Based Palliative Care Intervention in Kolkata, India.
, Calvo-Schimmel A.
, McGue S.
, Singh P.
, Roy R.
, Bhattacharjee G.
, Panda N.
, Kumar G.
, Chowdhury R.
, Cartmell K.B.
The American journal of hospice & palliative care, 2021 Jun; 38(6), p. 572-582.