Grant Details
Grant Number: |
5P50CA244688-02 Interpret this number |
Primary Investigator: |
Glasgow, Russell |
Organization: |
University Of Colorado Denver |
Project Title: |
Pragmatic Implementation Science Approaches to Assess and Enhance Value of Cancer Prevention and Control in Rural Primary Care |
Fiscal Year: |
2020 |
Abstract
Project Summary/Abstract – Overall
The theme of our proposed Implementation Science Center is “Pragmatic implementation science approaches
to assess and enhance the value of cancer prevention and control in rural primary care.” We will apply and
advance frameworks, pragmatic methods, and measures related to cost, benefits, and value that are rigorous,
but also generalizable across rural primary care settings that are often struggling with low resources, and a
high need population. These models and methods will be used to guide selection and implementation of
evidence-based programs for cancer prevention and control (CPC). We will initially focus on lung cancer
screening in rural primary care settings, first in Colorado and then nationally through collaboration with a well-
established primary care network (i.e., National Research Network).
Our overarching framework will be our enhanced RE-AIM/PRISM model, which is an extension of the broadly
used Reach, Effectiveness, Adoption, Implementation, and Maintenance framework with the addition of
contextual factors (e.g., Intervention characteristics, implementation and sustainability infrastructure). It will
serve as the basis to develop and test innovative assessments of costs, benefits, and value from the
perspective of different stakeholders to understand and guide implementation. We will meaningfully engage
with and include the perspectives of patients, providers, and staff stakeholders in all our studies. Our pilot
Implementation Study will adapt, implement, and evaluate strategies using stakeholder-engaged approaches
to value to guide the implementation of shared decision-making and smoking cessation related to lung cancer
screening.
Our Methods Unit will refine and evaluate our pragmatic cost assessment methods to determine
implementation/replication costs from the perspective(s) of patients, providers, and delivery staff and then
develop and pilot test brief survey measures of preferences regarding the relative benefit of different RE-AIM
outcomes. We will then assess relationships among RE-AIM outcomes preferences and selection of different
CPC programs. Finally, our Outreach and Network Unit will engage in a) outreach activities targeted at junior
and mid-career investigators and practitioners including online professional development (e.g., graduate
certificate program, micro-certification) and tailored mentoring and technical assistance approaches; b)
dissemination activities to support the packaging and communication of research findings; and c)
collaboration activities to facilitate partnerships on CPC and implementation science using multiple channels
and including development of shared pragmatic D&I measures and data.
Publications
Primary Care Research Is Hard to Do During COVID-19: Challenges and Solutions.
Authors: Holtrop J.S.
, Davis M.M.
.
Source: Annals of family medicine, 2022 Nov-Dec; 20(6), p. 568-572.
PMID: 36443077
Related Citations
How Dissemination and Implementation Science Can Contribute to the Advancement of Learning Health Systems.
Authors: Trinkley K.E.
, Ho P.M.
, Glasgow R.E.
, Huebschmann A.G.
.
Source: Academic medicine : journal of the Association of American Medical Colleges, 2022-10-01; 97(10), p. 1447-1458.
EPub date: 2022-09-23.
PMID: 35796045
Related Citations
Priorities for improvement across cancer and non-cancer related preventive services among rural and non-rural clinicians.
Authors: Brtnikova M.
, Studts J.L.
, Robertson E.
, Dickinson L.M.
, Carroll J.K.
, Krist A.H.
, Cronin J.T.
, Glasgow R.E.
.
Source: BMC primary care, 2022-09-09; 23(1), p. 231.
EPub date: 2022-09-09.
PMID: 36085005
Related Citations
Sex Differences in Physical Activity Among Individuals With Type 2 Diabetes Across the Life Span: A Systematic Review and Meta-analysis.
Authors: Whipple M.O.
, Pinto A.J.
, Abushamat L.A.
, Bergouignan A.
, Chapman K.
, Huebschmann A.G.
, Masters K.S.
, Nadeau K.J.
, Scalzo R.L.
, Schauer I.E.
, et al.
.
Source: Diabetes care, 2022-09-01; 45(9), p. 2163-2177.
PMID: 36044665
Related Citations
Environmental sensing mechanisms in intestinal homeostasis.
Authors: Mitson-Salazar A.
, Medzhitov R.
.
Source: The Journal of allergy and clinical immunology, 2022 Sep; 150(3), p. 577-579.
EPub date: 2022-07-09.
PMID: 35820536
Related Citations
Applying dissemination and implementation research methods to translate a school-based asthma program.
Authors: Szefler S.J.
, Cicutto L.
, Brewer S.E.
, Gleason M.
, McFarlane A.
, DeCamp L.R.
, Brinton J.T.
, Huebschmann A.G.
.
Source: The Journal of allergy and clinical immunology, 2022 Sep; 150(3), p. 535-548.
EPub date: 2022-05-13.
PMID: 35569568
Related Citations
Pragmatic considerations and approaches for measuring staff time as an implementation cost in health systems and clinics: key issues and applied examples.
Authors: Huebschmann A.G.
, Trinkley K.E.
, Gritz M.
, Glasgow R.E.
.
Source: Implementation science communications, 2022-04-15; 3(1), p. 44.
EPub date: 2022-04-15.
PMID: 35428326
Related Citations
Revisiting concepts of evidence in implementation science.
Authors: Brownson R.C.
, Shelton R.C.
, Geng E.H.
, Glasgow R.E.
.
Source: Implementation science : IS, 2022-04-12; 17(1), p. 26.
EPub date: 2022-04-12.
PMID: 35413917
Related Citations
Using economic evaluations in implementation science to increase transparency in costs and outcomes for organizational decision-makers.
Authors: Saldana L.
, Ritzwoller D.P.
, Campbell M.
, Block E.P.
.
Source: Implementation science communications, 2022-04-11; 3(1), p. 40.
EPub date: 2022-04-11.
PMID: 35410434
Related Citations
Designing for Dissemination and Sustainability to Promote Equitable Impacts on Health.
Authors: Kwan B.M.
, Brownson R.C.
, Glasgow R.E.
, Morrato E.H.
, Luke D.A.
.
Source: Annual review of public health, 2022-04-05; 43, p. 331-353.
EPub date: 2022-01-04.
PMID: 34982585
Related Citations
Values and Meaning in Rural Primary Care Practices: Implications for Interventions Within Context.
Authors: Holtrop J.S.
, Nederveld A.
, Lum H.D.
, Glasgow R.E.
, Gomes R.
.
Source: Journal of primary care & community health, 2022 Jan-Dec; 13, p. 21501319221139371.
PMID: 36433703
Related Citations
Dissemination and Implementation Science Approaches for Occupational Safety and Health Research: Implications for Advancing Total Worker Health.
Authors: Guerin R.J.
, Harden S.M.
, Rabin B.A.
, Rohlman D.S.
, Cunningham T.R.
, TePoel M.R.
, Parish M.
, Glasgow R.E.
.
Source: International journal of environmental research and public health, 2021-10-21; 18(21), .
EPub date: 2021-10-21.
PMID: 34769573
Related Citations
Implementation science issues in understanding, collecting, and using cost estimates: a multi-stakeholder perspective.
Authors: Eisman A.B.
, Quanbeck A.
, Bounthavong M.
, Panattoni L.
, Glasgow R.E.
.
Source: Implementation science : IS, 2021-08-03; 16(1), p. 75.
EPub date: 2021-08-03.
PMID: 34344411
Related Citations
Acute effects of sedentary breaks on vascular health in adults at risk for type 2 diabetes: A systematic review.
Authors: Whipple M.O.
, Masters K.S.
, Huebschmann A.G.
, Scalzo R.L.
, Reusch J.E.
, Bergouignan A.
, Regensteiner J.G.
.
Source: Vascular medicine (London, England), 2021 Aug; 26(4), p. 448-458.
EPub date: 2021-05-12.
PMID: 33977799
Related Citations
A Scoping Review and General User's Guide for Facilitating the Successful Use of eHealth Programs for Diabetes in Clinical Care.
Authors: Fisher L.
, Glasgow R.E.
, Huebschmann A.
.
Source: Diabetes technology & therapeutics, 2021 Feb; 23(2), p. 133-145.
EPub date: 2020-08-31.
PMID: 32865431
Related Citations
Roles dissemination and implementation scientists can play in supporting research teams.
Authors: Tabak R.G.
, Bauman A.A.
, Holtrop J.S.
.
Source: Implementation science communications, 2021-01-15; 2(1), p. 9.
EPub date: 2021-01-15.
PMID: 33451364
Related Citations
The Importance of Mental Models in Implementation Science.
Authors: Holtrop J.S.
, Scherer L.D.
, Matlock D.D.
, Glasgow R.E.
, Green L.A.
.
Source: Frontiers in public health, 2021; 9, p. 680316.
EPub date: 2021-07-06.
PMID: 34295871
Related Citations
Editorial: Use of the RE-AIM Framework: Translating Research to Practice With Novel Applications and Emerging Directions.
Authors: Estabrooks P.A.
, Gaglio B.
, Glasgow R.E.
, Harden S.M.
, Ory M.G.
, Rabin B.A.
, Smith M.L.
.
Source: Frontiers in public health, 2021; 9, p. 691526.
EPub date: 2021-06-11.
PMID: 34178933
Related Citations
Motivational Interviewing for Maternal Immunisation (MI4MI) study: a protocol for an implementation study of a clinician vaccine communication intervention for prenatal care settings.
Authors: Brewer S.E.
, Cataldi J.R.
, Fisher M.
, Glasgow R.E.
, Garrett K.
, O'Leary S.T.
.
Source: BMJ open, 2020-11-17; 10(11), p. e040226.
EPub date: 2020-11-17.
PMID: 33203635
Related Citations
What Can Implementation Science Do for You? Key Success Stories from the Field.
Authors: Kilbourne A.M.
, Glasgow R.E.
, Chambers D.A.
.
Source: Journal of general internal medicine, 2020 Nov; 35(Suppl 2), p. 783-787.
PMID: 33107001
Related Citations
Integrating the Practical Robust Implementation and Sustainability Model With Best Practices in Clinical Decision Support Design: Implementation Science Approach.
Authors: Trinkley K.E.
, Kahn M.G.
, Bennett T.D.
, Glasgow R.E.
, Haugen H.
, Kao D.P.
, Kroehl M.E.
, Lin C.T.
, Malone D.C.
, Matlock D.D.
.
Source: Journal of medical Internet research, 2020-10-29; 22(10), p. e19676.
EPub date: 2020-10-29.
PMID: 33118943
Related Citations
Characterizing evolving frameworks: issues from Esmail et al. (2020) review.
Authors: Glasgow R.E.
, Estabrooks P.A.
, Ory M.G.
.
Source: Implementation science : IS, 2020-07-02; 15(1), p. 53.
EPub date: 2020-07-02.
PMID: 32611414
Related Citations
Enhancing Success of Medicare's Shared Decision Making Mandates Using Implementation Science: Examples Applying the Pragmatic Robust Implementation and Sustainability Model (PRISM).
Authors: Matlock D.D.
, Fukunaga M.I.
, Tan A.
, Knoepke C.
, McNeal D.M.
, Mazor K.M.
, Glasgow R.E.
.
Source: MDM policy & practice, 2020 Jul-Dec; 5(2), p. 2381468320963070.
EPub date: 2020-10-15.
PMID: 33117890
Related Citations
Making Implementation Science More Rapid: Use of the RE-AIM Framework for Mid-Course Adaptations Across Five Health Services Research Projects in the Veterans Health Administration.
Authors: Glasgow R.E.
, Battaglia C.
, McCreight M.
, Ayele R.A.
, Rabin B.A.
.
Source: Frontiers in public health, 2020; 8, p. 194.
EPub date: 2020-05-27.
PMID: 32528921
Related Citations
An Extension of RE-AIM to Enhance Sustainability: Addressing Dynamic Context and Promoting Health Equity Over Time.
Authors: Shelton R.C.
, Chambers D.A.
, Glasgow R.E.
.
Source: Frontiers in public health, 2020; 8, p. 134.
EPub date: 2020-05-12.
PMID: 32478025
Related Citations
RE-AIM in the Real World: Use of the RE-AIM Framework for Program Planning and Evaluation in Clinical and Community Settings.
Authors: Kwan B.M.
, McGinnes H.L.
, Ory M.G.
, Estabrooks P.A.
, Waxmonsky J.A.
, Glasgow R.E.
.
Source: Frontiers in public health, 2019; 7, p. 345.
EPub date: 2019-11-22.
PMID: 31824911
Related Citations