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Grant Details

Grant Number: 5R01CA159954-08 Interpret this number
Primary Investigator: Marcus, Bess
Organization: Brown University
Project Title: Promoting Physical Activity in Latinas Via Interactive Web-Based Technology
Fiscal Year: 2020


Abstract In the U.S., Latina women report higher rates of inactivity than their non-Hispanic White and male counterparts, and are disproportionately affected by related health conditions (e.g., cancer, hypertension, heart disease, stroke, diabetes). To address this public health crisis, evidence-based interventions that utilize state-of-the-art technology, theory and methods are needed to increase physical activity (PA) among this high-risk population. Recently, our team conducted a randomized controlled trial (N=205) to test the efficacy of a 6-month culturally adapted, individually tailored, Spanish-language Internet-based PA intervention among Latinas (Pasos Hacia La Salud, R01CA159954) vs. a Wellness Contact Control Internet Group. Increases in minutes/week of moderate-to-vigorous physical activity (MVPA) were significantly greater in the Intervention Group compared to the Control Group at 6 and 12 months (p < .01) but still did not reach levels recommended in the national physical activity guidelines. As improvements in PA in the Intervention Group were significantly associated with website use and increases in self-efficacy, enjoyment, and social support in the parent study, we used these data to inform technology and theory-supported enhancements to the intervention (i.e., text messaging and adaptive goal setting to increase website use and further targeting of the previously mentioned key psychosocial constructs) to achieve even greater increases in PA, and maintain these gains over the long term (24 months) in the renewal of R01CA159954. For the proposed study, 300 Latina women will be randomized to either 1) the original Pasos Hacia La Salud tailored Internet-based PA intervention (Original Intervention) or 2) the data driven, enhanced version of the Pasos Hacia La Salud PA intervention (Enhanced Intervention). We hypothesize that participants in the Enhanced Intervention arm will report significantly more minutes/week of MVPA than participants in the Original Intervention arm at 6 months. We will also examine the maintenance of treatment effects at 12, 18, and 24 months, as well as the costs of delivering the Enhanced vs. Original Intervention programs, and the potential mediators of the intervention-PA relationship. The proposed high- reach, low-cost intervention holds great promise in promoting and maintaining the positive health benefits of PA in the lives of Latina women in the United States.


Pasos Hacia La Salud II: study protocol for a randomized controlled trial of a theory- and technology-enhanced physical activity intervention for Latina women, compared to the original intervention.
Authors: Mendoza-Vasconez A.S. , Benitez T. , Dunsiger S. , Gans K.M. , Hartman S.J. , Linke S.E. , Larsen B.A. , Pekmezi D. , Marcus B.H. .
Source: Trials, 2022-08-01; 23(1), p. 621.
EPub date: 2022-08-01.
PMID: 35915473
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Physical activity outcomes from a randomized trial of a theory- and technology-enhanced intervention for Latinas: the Seamos Activas II study.
Authors: Marcus B.H. , Dunsiger S. , Pekmezi D. , Benitez T. , Larsen B. , Meyer D. .
Source: Journal of behavioral medicine, 2022 02; 45(1), p. 1-13.
EPub date: 2021-08-11.
PMID: 34379236
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Psychosocial mediators of physical activity change in a web-based intervention for Latinas.
Authors: Larsen B. , Dunsiger S.I. , Pekmezi D. , Linke S. , Hartman S.J. , Marcus B.H. .
Source: Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2021 Jan; 40(1), p. 21-29.
EPub date: 2020-11-23.
PMID: 33370154
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Design and rationale for a randomized trial of a theory- and technology- enhanced physical activity intervention for Latinas: The Seamos Activas II study.
Authors: Benitez T.J. , Dunsiger S.I. , Pekmezi D.J. , Larsen B.A. , Mendoza-Vasconez A.S. , Linke S.E. , Bock B.C. , Gans K.M. , Hartman S.J. , Marcus B.H. .
Source: Contemporary clinical trials, 2020 09; 96, p. 106081.
EPub date: 2020-07-17.
PMID: 32687974
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Physical Activity Intervention Effects on Sedentary Time in Spanish-Speaking Latinas.
Authors: Hartman S.J. , Pekmezi D. , Dunsiger S.I. , Marcus B.H. .
Source: Journal of physical activity & health, 2020-03-01; 17(3), p. 343-348.
EPub date: 2020-03-01.
PMID: 32035412
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Assessing Maternal Support for Physical Activity in Latina Adolescents.
Authors: Benitez T.J. , Cano M. , Marquez B. , Larsen B. .
Source: American journal of health behavior, 2020-03-01; 44(2), p. 146-158.
PMID: 32019648
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Association Between Physical Activity Intervention Website Use and Physical Activity Levels Among Spanish-Speaking Latinas: Randomized Controlled Trial.
Authors: Linke S.E. , Dunsiger S.I. , Gans K.M. , Hartman S.J. , Pekmezi D. , Larsen B.A. , Mendoza-Vasconez A.S. , Marcus B.H. .
Source: Journal of medical Internet research, 2019-07-24; 21(7), p. e13063.
EPub date: 2019-07-24.
PMID: 31342902
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Psychometrics of the self-efficacy for physical activity scale among a Latina women sample.
Authors: Mendoza-Vasconez A.S. , Marquez B. , Benitez T.J. , Marcus B.H. .
Source: BMC public health, 2018-09-05; 18(1), p. 1097.
EPub date: 2018-09-05.
PMID: 30185171
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Weight and weight control behaviors of Latinas and their social ties.
Authors: Marquez B. , Norman G.J. , Fowler J.H. , Gans K.M. , Marcus B.H. .
Source: Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2018 04; 37(4), p. 318-325.
EPub date: 2018-02-01.
PMID: 29389157
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Egocentric networks and physical activity outcomes in Latinas.
Authors: Marquez B. , Norman G. , Fowler J. , Gans K. , Marcus B. .
Source: PloS one, 2018; 13(6), p. e0199139.
EPub date: 2018-06-18.
PMID: 29912935
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Physical activity maintenance among Spanish-speaking Latinas in a randomized controlled trial of an Internet-based intervention.
Authors: Hartman S.J. , Dunsiger S.I. , Bock B.C. , Larsen B.A. , Linke S. , Pekmezi D. , Marquez B. , Gans K.M. , Mendoza-Vasconez A.S. , Marcus B.H. .
Source: Journal of behavioral medicine, 2017 Jun; 40(3), p. 392-402.
EPub date: 2016-10-17.
PMID: 27752866
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A Web-Based Physical Activity Intervention for Spanish-Speaking Latinas: A Costs and Cost-Effectiveness Analysis.
Authors: Larsen B. , Marcus B. , Pekmezi D. , Hartman S. , Gilmer T. .
Source: Journal of medical Internet research, 2017-02-22; 19(2), p. e43.
EPub date: 2017-02-22.
PMID: 28228368
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Pasos Hacia La Salud: a randomized controlled trial of an internet-delivered physical activity intervention for Latinas.
Authors: Marcus B.H. , Hartman S.J. , Larsen B.A. , Pekmezi D. , Dunsiger S.I. , Linke S. , Marquez B. , Gans K.M. , Bock B.C. , Mendoza-Vasconez A.S. , et al. .
Source: The international journal of behavioral nutrition and physical activity, 2016-05-28; 13, p. 62.
EPub date: 2016-05-28.
PMID: 27234302
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Using interactive Internet technology to promote physical activity in Latinas: Rationale, design, and baseline findings of Pasos Hacia La Salud.
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Source: Contemporary clinical trials, 2015 Sep; 44, p. 149-158.
EPub date: 2015-08-05.
PMID: 26255237
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Authors: Marquez B. .
Source: Eating and weight disorders : EWD, 2015 Sep; 20(3), p. 345-53.
EPub date: 2014-12-07.
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Using Web-Based Technology to Promote Physical Activity in Latinas: Results of the Muévete Alabama Pilot Study.
Authors: Benitez T.J. , Cherrington A.L. , Joseph R.P. , Keller C. , Marcus B. , Meneses K. , Marquez B. , Pekmezi D. .
Source: Computers, informatics, nursing : CIN, 2015 Jul; 33(7), p. 315-24.
PMID: 26049367
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Source: Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015 Feb; 11(2), p. 226-35.
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