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National Institutes of Health: National Cancer Institute: Division of Cancer Control and Population Sciences
Grant Details

Grant Number: 5R01CA122128-05 Interpret this number
Primary Investigator: Brook, Judith
Organization: New York University School Of Medicine
Project Title: A Longitudinal Study of the Predictors of Smoking in Women in Late Midlife
Fiscal Year: 2012
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Abstract

DESCRIPTION (provided by applicant): The overall goals of this longitudinal study are to examine etiologic predictors and consequences of women's tobacco use and dependence in late midlife. Our focus related to the late midlife experience will be on the broader socioenvironmental context (e.g., neighborhood services and organizations, neighborhood cohesion, social network, and social support), in interaction with individual factors related to tobacco use and dependence, drug use, health, and psychopathology. The original sample in 1975 consisted of women whose average age was 32 (T1). Subsequently, the women were interviewed when their average age was 40 (T2), 42 (T3), and 47 (T4). A fifth data collection (T5) for the women is proposed when the participants are an average age of 62, in order to accomplish the following: (1) examine interrelations and interactions of personality (including psychopathology), family, friend, and socioenvironmental contextual factors as they relate to the course of tobacco use and dependence over time (i.e., stability and change) and cessation; (2) study the consequences of long-term tobacco use and dependence on women's psychopathology and functioning; and (3) examine the impact of tobacco dependence and cessation across two generations. Interviews will be conducted in the participants' homes by trained interviewers. Scales with adequate psychometric properties measuring the independent variables will be developed. The primary analytic techniques will be causal analysis, logistic regression analysis, and growth mixture modeling. The significance of this study for public health lies in the intrapersonal, interpersonal, and neighborhood longitudinal data available at several crucial stages of development. Since tobacco use is a major predictor of many adverse health outcomes in women (e.g., cancer), this study will have great relevance for the mission of the National Cancer Institute. Knowledge of the longitudinal pathways to tobacco dependence from age 32 to 62 and the cessation of tobacco use will help provide detailed and specific guidelines for treatment. This study is also unique in that the long-term effects of tobacco use and dependence can be evaluated for their cumulative impact. In addition, by identifying protective factors that can mitigate the adverse effects of tobacco use and dependence on women's functioning in late midlife, we can provide additional information necessary for effective treatment efforts and public policy. 7. PROJECT NARRATIVE Knowledge of the longitudinal pathways to tobacco dependence from age 32 to 62 and the cessation of tobacco use will help provide detailed and specific guidelines for treatment. This study is also unique in that the long-term effects of tobacco use and dependence can be evaluated for their cumulative impact. In addition, by identifying protective factors that can mitigate the adverse effects of tobacco use and dependence on women's functioning in late midlife, we can provide additional information necessary for effective treatment efforts and public policy.

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Publications

Better late than never: the perceived benefits of smoking cessation among women in late midlife.
Authors: Brook J.S. , Rubenstone E. , Zhang C. , Brook D.W. .
Source: Journal of addictive diseases, 2014; 33(3), p. 266-73.
PMID: 25115276
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Psychosocial factors related to smoking: the midlife study.
Authors: Brook J.S. , Zhang C. , Brook D.W. .
Source: The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, 2014 Sep-Oct; 23(5), p. 423-8.
EPub date: 2014-07-25.
PMID: 25065534
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Psychosocial Predictors of Mental Health Service Utilization Among Women During their Mid-Sixties.
Authors: Pahl K. , Brook J.S. , Zhang C. , Brook D.W. .
Source: The journal of behavioral health services & research, 2016 Apr; 43(2), p. 143-54.
PMID: 24878632
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Voluntary smoking bans at home and in the car and smoking cessation, obesity, and self-control.
Authors: Brook J.S. , Zhang C. , Brook D.W. , Finch S.J. .
Source: Psychological reports, 2014 Feb; 114(1), p. 20-31.
PMID: 24765707
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Personality characteristics in the mid-forties predict women's smoking cessation in their mid-sixties.
Authors: Brook J.S. , Zhang C. , Balka E.B. , Seltzer N. , Brook D.W. .
Source: Psychological reports, 2013 Dec; 113(3), p. 921-9.
PMID: 24693821
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The intergenerational transmission of smoking in adulthood: a 25-year study of maternal and offspring maladaptive attributes.
Authors: Brook J.S. , Rubenstone E. , Zhang C. , Finch S.J. , Brook D.W. .
Source: Addictive behaviors, 2013 Jul; 38(7), p. 2361-8.
EPub date: 2013-03-21.
PMID: 23602938
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The role of personal attributes in the genesis and progression of lung disease and cigarette smoking.
Authors: Brook A. , Zhang C. .
Source: American journal of public health, 2013 May; 103(5), p. 931-7.
EPub date: 2012-09-20.
PMID: 22994182
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Trajectories of cigarette smoking in adulthood predict insomnia among women in late mid-life.
Authors: Brook D.W. , Rubenstone E. , Zhang C. , Brook J.S. .
Source: Sleep medicine, 2012 Oct; 13(9), p. 1130-7.
EPub date: 2012-08-15.
PMID: 22901402
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Psychosocial predictors of nicotine dependence among women during their mid-sixties.
Authors: Brook J.S. , Zhang C. , Brook D.W. , Koppel J. , Whiteman M. .
Source: The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, 2012 Jul-Aug; 21(4), p. 302-12.
EPub date: 2012-04-12.
PMID: 22691008
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The smoking patterns of women in their forties: their relationship to later osteoporosis.
Authors: Brook J.S. , Balka E.B. , Zhang C. .
Source: Psychological reports, 2012 Apr; 110(2), p. 351-62.
PMID: 22662390
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Earlier joint trajectories of cigarette smoking and low perceived self-control as predictors of later poor health for women in their mid-60s.
Authors: Brook J.S. , Zhang C. , Brook D.W. , Finch S.J. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012 Apr; 14(4), p. 434-42.
EPub date: 2011-12-21.
PMID: 22193579
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Psychosocial predictors, higher body mass index, and aspects of neurocognitive dysfunction.
Authors: Brook J.S. , Zhang C. , Saar N.S. , Brook D.W. .
Source: Perceptual and motor skills, 2009 Feb; 108(1), p. 181-95.
PMID: 19425460
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