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Grant Details

Grant Number: 5R01CA087472-13 Interpret this number
Primary Investigator: Glantz, Stanton
Organization: University Of California, San Francisco
Project Title: Analysis of Tobacco Industry Documents
Fiscal Year: 2012
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Abstract

DESCRIPTION (provided by applicant): Smoking remains the leading preventable cause of death, accounting for one-third of all cancers and nearly two-thirds of heart disease among people under 55. Reducing tobacco-induced disease requires understanding how its vector, the tobacco industry, maintains a social and policy environment favorable to smoking. To understand a microbe, one might study its genome; the tobacco industry's "genome" is its written record of research and decision making in the form of over 51 million pages of previously secret internal tobacco industry documents. This application extends our current work to address tobacco industry influence on science and policy making in the emerging US and global regulatory environment, and to learn from the industry's promotional strategies targeting young adults and women to develop improved counter-measures. Specific aims are: (1) Describe and assess the tobacco industry's evolving strategies to influence the conduct, interpretation, and dissemination of science and how the industry has used these strategies to oppose tobacco control policies, with particular emphasis on how these efforts relate to emerging national and international product regulations by the US Food and Drug Administration and its counterparts in other countries. (2) Analyze evolving tobacco industry strategies to oppose tobacco control policies at the local, state, and international level, including efforts to undermine implementation of the World Health Organization Framework Convention on Tobacco Control. (3) Analyze tobacco marketing and advertising strategies aimed at young adults and women, with an emphasis on identifying principles that can be applied to develop more effective tobacco prevention and cessation strategies for these groups. (4) Continue to locate and collect tobacco industry documents relevant to the other Aims of this project and make them freely available to other investigators and the public via the Internet. While this research makes systematic use of digitized tobacco industry documents as a data source, we will also triangulate with other sources (including government records, media coverage of issues discussed in the documents, the academic literature and interviews with key informants) to confirm whether plans described in the documents were actually implemented and to assess their effect. Results of this research will guide the development of more informed and effective tobacco control strategies which will help reduce tobacco use and its associated burden of disease and death. PUBLIC HEALTH RELEVANCE: Smoking is the leading preventable cause of death, accounting for 1/3 of all cancers and nearly 2/3 of heart disease among people under 55. Reducing this burden of disease requires understanding how the tobacco industry maintains a favorable social and policy environment to promote smoking so that public health professionals can develop and implement effective programs to prevent smoking and promote cessation.

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Publications

Understanding tobacco-related attitudes among college and noncollege young adult hookah and cigarette users.
Authors: Lee YO, Bahreinifar S, Ling PM
Source: J Am Coll Health, 2014;62(1), p. 10-8.
PMID: 24313692
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The nature, scope, and development of the global tobacco control epistemic community.
Authors: Mamudu HM, Gonzalez M, Glantz S
Source: Am J Public Health, 2011 Nov;101(11), p. 2044-54.
EPub date: 2011 Sep 22.
PMID: 21940926
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Electronic nicotine delivery systems in the hands of Hollywood.
Authors: Grana RA, Glantz SA, Ling PM
Source: Tob Control, 2011 Nov;20(6), p. 425-6.
EPub date: 2011 Jun 9.
PMID: 21659450
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Endotoxins in tobacco smoke: shifting tobacco industry positions.
Authors: Barnes RL, Glantz SA
Source: Nicotine Tob Res, 2007 Oct;9(10), p. 995-1004.
PMID: 17852769
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Melanin and nicotine: A review of the literature.
Authors: Yerger VB, Malone RE
Source: Nicotine Tob Res, 2006 Aug;8(4), p. 487-98.
PMID: 16920646
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Eliminating child labour in Malawi: a British American Tobacco corporate responsibility project to sidestep tobacco labour exploitation.
Authors: Otaņez MG, Muggli ME, Hurt RD, Glantz SA
Source: Tob Control, 2006 Jun;15(3), p. 224-30.
PMID: 16728754
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Scientific analysis of second-hand smoke by the tobacco industry, 1929-1972.
Authors: Schick S, Glantz S
Source: Nicotine Tob Res, 2005 Aug;7(4), p. 591-612.
PMID: 16085530
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Taking it to the streets: responses of African American young adults to internal tobacco industry documents.
Authors: Yerger VB, Daniel MR, Malone RE
Source: Nicotine Tob Res, 2005 Feb;7(1), p. 163-72.
PMID: 15804689
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Tobacco industry surveillance of public health groups: the case of STAT (Stop Teenage Addiction to Tobacco) and INFACT (Infant Formula Action Coalition).
Authors: Malone RE
Source: Am J Public Health, 2002 Jun;92(6), p. 955-60.
PMID: 12036789
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How the tobacco industry built its relationship with Hollywood.
Authors: Mekemson C, Glantz SA
Source: Tob Control, 2002 Mar;11 Suppl 1, p. I81-91.
PMID: 11893818
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Nursing, our public deaths, and the tobacco industry.
Authors: Malone RE
Source: Am J Crit Care, 2002 Mar;11(2), p. 102-5.
PMID: 11888121
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