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Grant Details

Grant Number: 3U01CA086082-10S2 Interpret this number
Primary Investigator: Onega, Tracy
Organization: Dartmouth College
Project Title: New Hampshire Mammography Registry: Strategic Studies in Screening
Fiscal Year: 2011
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Abstract

The overarching goal of our proposed infrastructure support project is to promote ongoing data collection using a well-established and vital infrastructure in the New Hampshire Mammography Network (NHMN) (statewide mammography registry) so that we can conduct and promote important research designed to understand and address the problem of breast cancer in NH and beyond. The NHMN, which was implemented in 1996 efficiently obtains demographic, risk factor, and radiologic data on ~ 90% of women having mammography in NH, and then links mammographic encounter information to breast pathology outcomes. The registry has matured to a point where expanded use .ofthis resource for additional research is timely, which will depend on continued support of the NHMN infrastructure. Many studies have been conducted using the NHMN and several more studies have been submitted, which will be described later in this application. Our Specific Aims are to: 1) Continue and refine current NHMN procedures, including data collection, pathology linkages, feedback reports to mammography facilities and radiologists, and data submissionsto a centralized statistical coordinating center; and 2) Promote the use of NHMN and Consortium data locally, regionally, and regionally. Enrollment in NHMN involves obtaining women's consent to allow access to their medical records and to having themselves or their primary care providers contacted for detailed information about their health and future research. We have a successful track record of conducting research with women and their healthcare providers, including mammographytechnologists, radiologists, pathologists, breast surgeons, and primary health care providers throughout NH. We propose to use these strengths to advance our understanding of breast cancer detection.

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Publications

When radiologists perform best: the learning curve in screening mammogram interpretation.
Authors: Miglioretti DL, Gard CC, Carney PA, Onega TL, Buist DS, Sickles EA, Kerlikowske K, Rosenberg RD, Yankaskas BC, Geller BM, Elmore JG
Source: Radiology, 2009 Dec;253(3), p. 632-40.
EPub date: 2009 Sep 29.
PMID: 19789234
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Decreased accuracy in interpretation of community-based screening mammography for women with multiple clinical risk factors.
Authors: Cook AJ, Elmore JG, Miglioretti DL, Sickles EA, Aiello Bowles EJ, Cutter GR, Carney PA
Source: J Clin Epidemiol, 2010 Apr;63(4), p. 441-51.
EPub date: 2009 Sep 9.
PMID: 19744825
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Radiologists' performance and their enjoyment of interpreting screening mammograms.
Authors: Geller BM, Bowles EJ, Sohng HY, Brenner RJ, Miglioretti DL, Carney PA, Elmore JG
Source: AJR Am J Roentgenol, 2009 Feb;192(2), p. 361-9.
PMID: 19155395
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Predictors of radiologists' perceived risk of malpractice lawsuits in breast imaging.
Authors: Dick JF 3rd, Gallagher TH, Brenner RJ, Yi JP, Reisch LM, Abraham L, Miglioretti DL, Carney PA, Cutter GR, Elmore JG
Source: AJR Am J Roentgenol, 2009 Feb;192(2), p. 327-33.
PMID: 19155390
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Obesity, mammography use and accuracy, and advanced breast cancer risk.
Authors: Kerlikowske K, Walker R, Miglioretti DL, Desai A, Ballard-Barbash R, Buist DS
Source: J Natl Cancer Inst, 2008 Dec 3;100(23), p. 1724-33.
EPub date: 2008 Nov 25.
PMID: 19033562
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Mammography facility characteristics associated with interpretive accuracy of screening mammography.
Authors: Taplin S, Abraham L, Barlow WE, Fenton JJ, Berns EA, Carney PA, Cutter GR, Sickles EA, Carl D, Elmore JG
Source: J Natl Cancer Inst, 2008 Jun 18;100(12), p. 876-87.
EPub date: 2008 Jun 10.
PMID: 18544742
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Accuracy of short-interval follow-up mammograms by patient and radiologist characteristics.
Authors: Aiello Bowles EJ, Miglioretti DL, Sickles EA, Abraham L, Carney PA, Yankaskas BC, Elmore JG
Source: AJR Am J Roentgenol, 2008 May;190(5), p. 1200-8.
PMID: 18430832
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Joint modeling of sensitivity and specificity.
Authors: Puggioni G, Gelfand AE, Elmore JG
Source: Stat Med, 2008 May 10;27(10), p. 1745-61.
PMID: 18167634
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Radiologist characteristics associated with interpretive performance of diagnostic mammography.
Authors: Miglioretti DL, Smith-Bindman R, Abraham L, Brenner RJ, Carney PA, Bowles EJ, Buist DS, Elmore JG
Source: J Natl Cancer Inst, 2007 Dec 19;99(24), p. 1854-63.
EPub date: 2007 Dec 11.
PMID: 18073379
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Breast density in relation to risk of ductal carcinoma in situ of the breast in women undergoing screening mammography.
Authors: MacKenzie TA, Titus-Ernstoff L, Vacek PM, Geller B, Weiss JE, Goodrich ME, Carney PA
Source: Cancer Causes Control, 2007 Nov;18(9), p. 939-45.
EPub date: 2007 Jul 19.
PMID: 17638106
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Evidence-based target recall rates for screening mammography.
Authors: Schell MJ, Yankaskas BC, Ballard-Barbash R, Qaqish BF, Barlow WE, Rosenberg RD, Smith-Bindman R
Source: Radiology, 2007 Jun;243(3), p. 681-9.
PMID: 17517927
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Reactions to uncertainty and the accuracy of diagnostic mammography.
Authors: Carney PA, Yi JP, Abraham LA, Miglioretti DL, Aiello EJ, Gerrity MS, Reisch L, Berns EA, Sickles EA, Elmore JG
Source: J Gen Intern Med, 2007 Feb;22(2), p. 234-41.
PMID: 17356992
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Marginal modeling of nonnested multilevel data using standard software.
Authors: Miglioretti DL, Heagerty PJ
Source: Am J Epidemiol, 2007 Feb 15;165(4), p. 453-63.
EPub date: 2006 Nov 22.
PMID: 17121864
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Breast cancer risk factors in relation to breast density (United States).
Authors: Titus-Ernstoff L, Tosteson AN, Kasales C, Weiss J, Goodrich M, Hatch EE, Carney PA
Source: Cancer Causes Control, 2006 Dec;17(10), p. 1281-90.
PMID: 17111260
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Reality check: perceived versus actual performance of community mammographers.
Authors: Fenton JJ, Egger J, Carney PA, Cutter G, D'Orsi C, Sickles EA, Fosse J, Abraham L, Taplin SH, Barlow W, Hendrick RE, Elmore JG
Source: AJR Am J Roentgenol, 2006 Jul;187(1), p. 42-6.
PMID: 16794153
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Changes in newspaper coverage about hormone therapy with the release of new medical evidence.
Authors: Haas JS, Geller B, Miglioretti DL, Buist DS, Nelson DE, Kerlikowske K, Carney PA, Breslau ES, Dash S, Canales MK, Ballard-Barbash R
Source: J Gen Intern Med, 2006 Apr;21(4), p. 304-9.
EPub date: 2006 Feb 22.
PMID: 16499542
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Pathologic findings from the Breast Cancer Surveillance Consortium: population-based outcomes in women undergoing biopsy after screening mammography.
Authors: Weaver DL, Rosenberg RD, Barlow WE, Ichikawa L, Carney PA, Kerlikowske K, Buist DS, Geller BM, Key CR, Maygarden SJ, Ballard-Barbash R
Source: Cancer, 2006 Feb 15;106(4), p. 732-42.
PMID: 16411214
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Hormone therapies in women aged 40 and older: prevalence and correlates of use.
Authors: Carney PA, Tosteson AN, Titus-Ernstoff L, Weiss JE, Goodrich ME, Manganiello P, Kasales CJ
Source: Maturitas, 2006 Jan 10;53(1), p. 65-76.
PMID: 16325024
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Utilization of screening mammography in New Hampshire: a population-based assessment.
Authors: Carney PA, Goodrich ME, Mackenzie T, Weiss JE, Poplack SP, Wells WS, Titus-Ernstoff L
Source: Cancer, 2005 Oct 15;104(8), p. 1726-32.
PMID: 16158386
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Impact of a telephone counseling intervention on transitions in stage of change and adherence to interval mammography screening (United States).
Authors: Carney PA, Harwood BG, Greene MA, Goodrich ME
Source: Cancer Causes Control, 2005 Sep;16(7), p. 799-807.
PMID: 16132790
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Does litigation influence medical practice? The influence of community radiologists' medical malpractice perceptions and experience on screening mammography.
Authors: Elmore JG, Taplin SH, Barlow WE, Cutter GR, D'Orsi CJ, Hendrick RE, Abraham LA, Fosse JS, Carney PA
Source: Radiology, 2005 Jul;236(1), p. 37-46.
PMID: 15987961
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Mammographers' perception of women's breast cancer risk.
Authors: Egger JR, Cutter GR, Carney PA, Taplin SH, Barlow WE, Hendrick RE, D'Orsi CJ, Fosse JS, Abraham L, Elmore JG
Source: Med Decis Making, 2005 May-Jun;25(3), p. 283-9.
PMID: 15951455
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Accuracy of screening mammography interpretation by characteristics of radiologists.
Authors: Barlow WE, Chi C, Carney PA, Taplin SH, D'Orsi C, Cutter G, Hendrick RE, Elmore JG
Source: J Natl Cancer Inst, 2004 Dec 15;96(24), p. 1840-50.
PMID: 15601640
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Likelihood of additional work-up among women undergoing routine screening mammography: the impact of age, breast density, and hormone therapy use.
Authors: Carney PA, Kasales CJ, Tosteson AN, Weiss JE, Goodrich ME, Poplack SP, Wells WS, Titus-Ernstoff L
Source: Prev Med, 2004 Jul;39(1), p. 48-55.
PMID: 15207985
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