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Grant Details

Grant Number: 5R01CA084225-08 Interpret this number
Primary Investigator: Severson, Herbert
Organization: Oregon Research Institute
Project Title: Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users
Fiscal Year: 2011
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Abstract

DESCRIPTION (provided by applicant): Many Americans engage in the habitual use of smokeless tobacco (ST) and wish to quit but lack the resources. There is a need for innovative, validated, and easily-delivered low cost interventions to help ST users quit using tobacco. This project takes advantage of the opportunity to study two tobacco cessation interventions that are growing in use but still need more systematic evaluation: (1) The use of the Internet for health information and tobacco cessation has been growing in popularity, and our recently-completed study (Chewfree.com) demonstrated the efficacy of a Web-delivered ST cessation program; (2) Tobacco quitlines are now available in all 50 states and have demonstrated promising results in empirical studies with smokers, and they are widely used by ST users. We propose to build on the work of two complementary and well- established research teams at ORI and UCSD to test the effectiveness of combining an interactive Web-based intervention with a quitline that provides telephone counseling for ST cessation. We plan to use a 2x2 design and 2,440 participants to test for the individual main effects of the Web program and phone counseling as well as to examine the added value when these treatment approaches are combined. Outcome measures include prolonged abstinence over a 6-month follow-up period. In addition to the tobacco cessation outcomes we will assess mediational processes through which each intervention condition may affect tobacco abstinence. We will also perform an economic analysis to evaluate the relative cost-effectiveness of offering these programs. This will be the first study to assess the efficacy of telephone helpline counseling for smokeless tobacco (snuff and chewing tobacco) cessation and also the first to test the relative value of adding Web-assisted cessation to a telephone quitline. Because of their broad reach, relatively low cost per user, and their promising results in empirical studies, both telephone counseling quitlines and Web-based interventions are emerging as important public health interventions for tobacco cessation. To date there has not been a test of these approaches when targeted to smokeless tobacco users. By seeking to answer questions about the individual and combined effectiveness of these promising approaches, and assessing the relative cost of delivering these programs, the proposed randomized controlled trial will help define best practices for ST cessation and could maximize the public health benefits of their use.

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Publications

Modeling missing binary outcome data in a successful web-based smokeless tobacco cessation program.
Authors: Smolkowski K, Danaher BG, Seeley JR, Kosty DB, Severson HH
Source: Addiction, 2010 Jun;105(6), p. 1005-15.
EPub date: 2010 Feb 8.
PMID: 20148782
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Methodological issues in research on web-based behavioral interventions.
Authors: Danaher BG, Seeley JR
Source: Ann Behav Med, 2009 Aug;38(1), p. 28-39.
PMID: 19806416
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Mediators of a successful web-based smokeless tobacco cessation program.
Authors: Danaher BG, Smolkowski K, Seeley JR, Severson HH
Source: Addiction, 2008 Oct;103(10), p. 1706-12.
PMID: 18715238
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ChewFree.com: evaluation of a Web-based cessation program for smokeless tobacco users.
Authors: Severson HH, Gordon JS, Danaher BG, Akers L
Source: Nicotine Tob Res, 2008 Feb;10(2), p. 381-91.
PMID: 18236303
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Use of smokeless tobacco is a risk factor for cigarette smoking.
Authors: Severson HH, Forrester KK, Biglan A
Source: Nicotine Tob Res, 2007 Dec;9(12), p. 1331-7.
PMID: 18058351
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Measuring participant rurality in Web-based interventions.
Authors: Danaher BG, Hart LG, McKay HG, Severson HH
Source: BMC Public Health, 2007 Aug 31;7, p. 228.
EPub date: 2007 Aug 31.
PMID: 17764564
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Successful participant recruitment strategies for an online smokeless tobacco cessation program.
Authors: Gordon JS, Akers L, Severson HH, Danaher BG, Boles SM
Source: Nicotine Tob Res, 2006 Dec;8 Suppl 1, p. S35-41.
PMID: 17491169
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Self-help cessation programs for smokeless tobacco users: long-term follow-up of a randomized trial.
Authors: Severson HH, Andrews JA, Lichtenstein E, Danaher BG, Akers L
Source: Nicotine Tob Res, 2007 Feb;9(2), p. 281-9.
PMID: 17365759
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Defining participant exposure measures in Web-based health behavior change programs.
Authors: Danaher BG, Boles SM, Akers L, Gordon JS, Severson HH
Source: J Med Internet Res, 2006 Aug 30;8(3), p. e15.
EPub date: 2006 Aug 30.
PMID: 16954125
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