|Grant Number:||5R01CA123245-04 Interpret this number|
|Primary Investigator:||Greiner, K|
|Organization:||University Of Kansas Medical Center|
|Project Title:||Tailored Touchscreen Colorectal Cancer Prevention in Urban Core Clinics|
DESCRIPTION (provided by applicant): Colorectal cancer (CRC) mortality disproportionately impacts those with low income. Few studies have addressed screening among low income individuals in primary care. Unique strategies may be needed to surmount the limited awareness, fear and perceived discomfort that some low-income individuals associate with CRC screening tests. This study will assess the efficacy of a novel tailored touch screen computer intervention based on an innovative integration of the Precaution Adoption Process Model (PAPM) and the concept of "implementation intentions," a highly significant recent elaboration of the Theory of Planned Behavior. The majority of the intervention will be delivered in primary care settings on low-cost touch screen computers through multimedia audio-narrative and video messages. Studies have not tested the effectiveness of tailored communications specified to stated "implementation intentions" for improving CRC screening. A randomized design will test a comparison condition of generic information versus a multimedia tailored intervention that specifically addresses each participant's screening test modality preference, current CRC screening decisional stage (PAPM), and CRC screening "implementation intentions" (the "when," "where" and "how" details of screening). Behavioral intervention materials in English and Spanish will be developed with the help of cultural experts, pilot tests, and from focus groups that will test salience and cultural appropriateness of audio, video and graphic messages for low-income minorities and whites. The study will be conducted with 460 patients eligible for CRC screening and recruited while presenting for care in urban clinics. All participants will receive a baseline touch screen administered assessment and, depending on stated preference, be offered either an immunochemical fecal occult blood test (iFOBT-lnSure(tm)), colonoscopy, or sigmoidoscopy. Participants will be randomized to either C (comparison group-computer delivered generic CRC information) or Tl2 (active intervention-computer delivered tailored messaging based on individual PAPM stage, behavioral constructs, and "Implementation Intentions"). A brief office exit survey will assess patient-provider discussions of CRC screening and satisfaction with computerized message materials. A 90-day post randomization follow-up telephone call assessment with all participants will reassess PAPM stage and perceived CRC screening barriers. The primary outcome will be CRC screening completion at 90 days. Secondary outcomes will assess 90-day PAPM stage and perceived barriers among participants preferring various screening methods (sigmoidoscopy, colonoscopy, iFOBT). This intervention will provide information on the utility of embedding a low-cost technologically advanced "Implementation Intentions" based behavioral intervention in primary care practice.
Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups.
Authors: Hester CM, Jala VR, Langille MG, Umar S, Greiner KA, Haribabu B
Source: World J Gastroenterol, 2015 Mar 7;21(9), p. 2759-69.
Implementation intentions and colorectal screening: a randomized trial in safety-net clinics.
Authors: Greiner KA, Daley CM, Epp A, James A, Yeh HW, Geana M, Born W, Engelman KK, Shellhorn J, Hester CM, LeMaster J, Buckles DC, Ellerbeck EF
Source: Am J Prev Med, 2014 Dec;47(6), p. 703-14.
EPub date: 2014 Nov 18.
Modeling and validating Bayesian accrual models on clinical data and simulations using adaptive priors.
Authors: Jiang Y, Simon S, Mayo MS, Gajewski BJ
Source: Stat Med, 2015 Feb 20;34(4), p. 613-29.
EPub date: 2014 Nov 6.
Racial/Ethnic Variations in Colorectal Cancer Screening Self-Efficacy, Fatalism and Risk Perception in a Safety-Net Clinic Population: Implications for Tailored Interventions.
Authors: Lumpkins C, Cupertino P, Young K, Daley C, Yeh H, Greiner K
Source: J Community Med Health Educ, 2013 Jan 25;3, p. null.
Self-reported barriers to colorectal cancer screening in a racially diverse, low-income study population.
Authors: Quick BW, Hester CM, Young KL, Greiner KA
Source: J Community Health, 2013 Apr;38(2), p. 285-92.
A computerized intervention to promote colorectal cancer screening for underserved populations: theoretical background and algorithm development.
Authors: Greiner KA, Geana MV, Epp A, Watson A, Filippi M, Daley CM, Engelman KK, James AS, Campbell M
Source: Technol Health Care, 2012;20(1), p. 25-35.
Promoting healthy behavior from the pulpit: clergy share their perspectives on effective health communication in the African American church.
Authors: Lumpkins CY, Greiner KA, Daley C, Mabachi NM, Neuhaus K
Source: J Relig Health, 2013 Dec;52(4), p. 1093-107.