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Grant Details

Grant Number: 5R03CA126409-02 Interpret this number
Primary Investigator: Simmons, Vani
Organization: H. Lee Moffitt Cancer Ctr & Res Inst
Project Title: Smoking Relapse Among Lung Cancer and Head and Neck Cancer Patients
Fiscal Year: 2008
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Abstract

DESCRIPTION (provided by applicant): Cigarette smoking accounts for 85% of head and neck cancers and 90% of lung cancer cases. Once a smoker has been diagnosed with cancer, immediate smoking cessation is warranted because continued smoking is related to several adverse health outcomes for cancer patients, including: a reduction in treatment efficacy, an increased risk of developing a second primary cancer, and poorer survival. For these reasons, a high proportion of patients will quit smoking after receiving a cancer diagnosis (42-68%). Unfortunately, there is little information regarding the extent to which cancer patients are able to maintain their abstinence. Studies on smoking relapse among cancer patients have been scant and have had important methodological limitations (e.g., measuring rates of relapse in the context of an intervention study, infrequent follow-up). The large number of cancer patients making a quit attempt offers a unique window of opportunity to provide a relapse- prevention intervention; yet, to date, none have been developed. Thus, the current study seeks to acquire the knowledge needed to develop a smoking relapse intervention designed for cancer patients. Testing both empirically-based and theory-based relapse risk factors (e.g., negative affect, motivation), as well as cancer specific risk factors (e.g., fatigue, fear of cancer recurrence), will aid in the development of a targeted smoking relapse intervention. The formative and quantitative findings from this project will be used in a future study to adapt relapse prevention interventions, previously demonstrated efficacious, to address the unique needs and significant smoking relapse risk factors of cancer patients. Specific Aim 1: The overarching aim of this study is to gather data on smoking relapse among lung cancer and head and neck cancer patients, with the ultimate goal of developing a relapse prevention intervention for this population. Specific Aim 2: To identify patient perspectives on predictors of smoking relapse, intervention content, and format, via qualitative research methods. Specific Aim 3: To investigate empirically the precipitating events and predictors of smoking relapse among lung cancer and head and neck cancer patients. Efforts aimed at maintaining tobacco abstinence among this population could have significant public health implications, including improved physical functioning, quality of life, and survival for cancer patients. The overarching aim of this study is to gather data on smoking relapse among lung cancer and head and neck cancer patients, with the ultimate goal of developing a relapse prevention intervention for this population. Efforts aimed at maintaining tobacco abstinence among this population could have significant public health implications, including improved physical functioning, quality of life, and survival for cancer patients.

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Publications

Post-operative smoking status in lung and head and neck cancer patients: association with depressive symptomatology, pain, and fatigue.
Authors: Bloom EL, Oliver JA, Sutton SK, Brandon TH, Jacobsen PB, Simmons VN
Source: Psychooncology, 2014 Sep 25;null, p. null.
EPub date: 2014 Sep 25.
PMID: 25257853
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Predictors of smoking relapse in patients with thoracic cancer or head and neck cancer.
Authors: Simmons VN, Litvin EB, Jacobsen PB, Patel RD, McCaffrey JC, Oliver JA, Sutton SK, Brandon TH
Source: Cancer, 2013 Apr 1;119(7), p. 1420-7.
EPub date: 2012 Dec 20.
PMID: 23280005
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Oncology healthcare providers' implementation of the 5A's model of brief intervention for smoking cessation: patients' perceptions.
Authors: Simmons VN, Litvin EB, Unrod M, Brandon TH
Source: Patient Educ Couns, 2012 Mar;86(3), p. 414-9.
EPub date: 2011 Jul 23.
PMID: 21784598
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A measure of smoking abstinence-related motivational engagement: development and initial validation.
Authors: Simmons VN, Heckman BW, Ditre JW, Brandon TH
Source: Nicotine Tob Res, 2010 Apr;12(4), p. 432-7.
EPub date: 2010 Feb 26.
PMID: 20190004
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Patient-provider communication and perspectives on smoking cessation and relapse in the oncology setting.
Authors: Simmons VN, Litvin EB, Patel RD, Jacobsen PB, McCaffrey JC, Bepler G, Quinn GP, Brandon TH
Source: Patient Educ Couns, 2009 Dec;77(3), p. 398-403.
EPub date: 2009 Oct 20.
PMID: 19846270
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