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Grant Details

Grant Number: 5R03CA113086-02 Interpret this number
Primary Investigator: Mosavel, Maghboeba
Organization: Case Western Reserve University
Project Title: Cervical Cancer and the Mother-Daughter Relationship
Fiscal Year: 2006
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Abstract

DESCRIPTION (provided by applicant): Cervical cancer is a largely preventable disease when women receive regular pap smears. Estimates suggest that the introduction of pap smears to populations naive to screening reduces cervical cancer rates by 60-90% within three years of implementation. However, many women do not obtain screening because they know little about cervical cancer, fear the prospect of having a pap smear, or remain fatalistic about their health. Cervical cancer remains a major global problem. In South Africa, where we propose to conduct this study, cervical cancer is currently the second most common female cancer. The risk of developing cervical cancer for black South African women is 1 in 29. This extraordinarily high risk has been attributed, among other factors, to a lack of educational efforts aimed at informing women about cervical cancer and motivating them to utilize existing screening resources. In an effort to explore innovative and culturally appropriate strategies to promote screening, we have developed two specific aims: 1) explore the cervical cancer-related knowledge and behaviors of mothers and 2) explore the mother-daughter relationship and its potential for daughter-initiated cervical cancer prevention. This study plans to meet the first object through conducting focus groups with mothers. The second objective will be met by conducting semi-structured interviews to explore in-depth the dimensions of the mother-daughter relationship and the norms associated with advice giving and receiving, particularly health advice. Each of these aims will contribute formative data to better understand the potential of using daughters as advocates to promote cervical cancer screening with their mothers. Effective and innovative methods are needed to help promote screening for cervical cancer. The mother-daughter relationship offers unexplored opportunities for health promotion research and in particular for emphasizing the importance of pap smears. Finally, the mother-daughter relationship has implications for effecting inter-generational prevention behavior for cervical cancer.

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Publications

Community researchers conducting health disparities research: Ethical and other insights from fieldwork journaling.
Authors: Mosavel M, Ahmed R, Daniels D, Simon C
Source: Soc Sci Med, 2011 Jul;73(1), p. 145-52.
EPub date: 2011 May 30.
PMID: 21680071
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Young Adult Humans Health Services Research
Research Personnel Uterine Cervical Neoplasms Consumer Participation
Writing Adult Health Status Disparities
Interviews as Topic Data Collection South Africa
Adolescent Female

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Getting personal: ethics and identity in global health research.
Authors: Simon C, Mosavel M
Source: Dev World Bioeth, 2011 Aug;11(2), p. 82-92.
EPub date: 2011 Mar 22.
PMID: 21426482
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Researcher-Subject Relations Politics Humans
Clinical Trials as Topic Social Identification Community-Based Participatory Research
Developed Countries Research Personnel Role
Social Justice Developing Countries Truth Disclosure
Residence Characteristics Ethics, Research Social Responsibility
Mass Media Research Support as Topic

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Health promotion and cervical cancer in South Africa: why adolescent daughters can teach their mothers about early detection.
Authors: Mosavel M
Source: Health Promot Int, 2012 Jun;27(2), p. 157-66.
EPub date: 2011 Mar 18.
PMID: 21421580
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Questionnaires Motivation Humans
Mothers Nuclear Family Health Promotion
Socioeconomic Factors Uterine Cervical Neoplasms Adult
Vaginal Smears Middle Aged South Africa
Adolescent Female

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Cancer perceptions of South African mothers and daughters: implications for health promotion programs.
Authors: Mosavel M, Simon C, Ahmed R
Source: Health Care Women Int, 2010 Sep;31(9), p. 784-800.
PMID: 20677037
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1 NCI NIH HHS - R03 CA113086

MeSH Terms:
Emotions Death Humans
Mother-Child Relations Mothers Nuclear Family
Health Promotion Neoplasms Adult
Health Knowledge, Attitudes, Practice Middle Aged South Africa
Adolescent Urban Population Female

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Community members as recruiters of human subjects: ethical considerations.
Authors: Simon C, Mosavel M
Source: Am J Bioeth, 2010 Mar;10(3), p. 3-11.
PMID: 20229402
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1 NCI NIH HHS - CA 113086

MeSH Terms:
Humans Research Subjects Patient Selection
Peer Group Community-Based Participatory Research Research Design
Selection Bias International Cooperation Trust
Sampling Studies Coercion Informed Consent
Social Support South Africa

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Response to open peer commentaries on "Community members as recruiters of human subjects: ethical considerations".
Authors: Simon C, Mosavel M
Source: Am J Bioeth, 2010 Mar;10(3), p. W1-3.
PMID: 20229401
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Humans Research Subjects Patient Selection
Peer Group Community-Based Participatory Research Research Design
Selection Bias International Cooperation Trust
Sampling Studies Coercion Informed Consent
Social Support South Africa Ethics, Research

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Exploratory Health Disparities Research: The Need to Provide a Tangible Benefit to Vulnerable Respondents.
Authors: Mosavel M, Simon C
Source: Ethics Behav, 2010;20(1), p. 1-9.
PMID: 22211053
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-02

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Cervical cancer attitudes and beliefs-a Cape Town community responds on World Cancer Day.
Authors: Mosavel M, Simon C, Oakar C, Meyer S
Source: J Cancer Educ, 2009;24(2), p. 114-9.
PMID: 19431027
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Young Adult Culture Anxiety
Humans Cross-Cultural Comparison Aged
Health Education Uterine Cervical Neoplasms Mass Screening
Adult Health Knowledge, Attitudes, Practice Vaginal Smears
Middle Aged Female

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Daughter-initiated health advice to mothers: perceptions of African-American and Latina daughters.
Authors: Mosavel M, Thomas T
Source: Health Educ Res, 2009 Oct;24(5), p. 799-810.
EPub date: 2009 Apr 1.
PMID: 19339373
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA 113086

MeSH Terms:
Women's Health Humans Mother-Child Relations
Cross-Cultural Comparison African Americans Child
Health Promotion Hispanic Americans Health Behavior
Health Status Disparities Midwestern United States Adolescent
Female

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Key conceptual issues in the forging of "culturally competent" community health initiatives: a South African example.
Authors: Simon C, Mosavel M
Source: Camb Q Healthc Ethics, 2008 Spring;17(2), p. 195-205.
PMID: 18312734
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Socioeconomic Factors Cultural Characteristics Public Health
Unemployment Humans Cultural Competency
South Africa Residence Characteristics Community-Institutional Relations
Urban Population Health Promotion

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Ethical challenges in the design and conduct of locally relevant international health research.
Authors: Simon C, Mosavel M, van Stade D
Source: Soc Sci Med, 2007 May;64(9), p. 1960-9.
EPub date: 2007 Feb 26.
PMID: 17321657
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-02 NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Uterine Cervical Neoplasms Focus Groups Biomedical Research
Humans South Africa Adolescent
Research Design Internationality Male
Female

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The mother-daughter relationship: what is its potential as a locus for health promotion?
Authors: Mosavel M, Simon C, Van Stade D
Source: Health Care Women Int, 2006 Aug;27(7), p. 646-64.
PMID: 16844676
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-02 NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Cultural Characteristics Questionnaires Humans
Mother-Child Relations Mothers Health Promotion
Intergenerational Relations Poverty Adult
Health Knowledge, Attitudes, Practice South Africa Adolescent
Female

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Community-based participatory research (CBPR) in South Africa: engaging multiple constituents to shape the research question.
Authors: Mosavel M, Simon C, van Stade D, Buchbinder M
Source: Soc Sci Med, 2005 Dec;61(12), p. 2577-87.
EPub date: 2005 Jun 13.
PMID: 15955605
Related Citations

Grant Numbers:
NCI NIH HHS - R03 CA113086-02 NCI NIH HHS - R03 CA113086-01A1

MeSH Terms:
Health Services Needs and Demand Humans Health Services Research
Medically Underserved Area Community Health Planning Health Promotion
Uterine Cervical Neoplasms Focus Groups Consumer Participation
Mass Screening Adult Program Development
Interviews as Topic South Africa Female
Health Priorities

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