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Grant Details

Grant Number: 3R01HL062156-04S1 Interpret this number
Primary Investigator: Toobert, Deborah
Organization: Oregon Research Institute
Project Title: Enhancing Support for Women at Risk for Heart Disease
Fiscal Year: 2003
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Abstract

ABSTRACT=The overall goal of this project is to test a practical, theory- based intervention to achieve long-term behavior change for women with Type 2 diabetes at high risk for developing coronary heart disease (CHD). Epidemiological and clinical studies suggest that diabetes is associated with increased risk for CHD that is greater in women than in men. CHD is a major cause of death and functional limitations in women, but the vast majority of CHD studies have primarily involved middle-aged men. There is convincing research evidence that healthy lifestyle behaviors, including low-fat diet, physical activity, stress management, smoking cessation, and social support, can reduce CHD risk. We will conduct a randomized trial to compare short-term (6-month) outcomes in women receiving usual care compared to a modified Ornish-type comprehensive lifestyle management (CLM) intervention. After 6 months, women in the CLM condition will be randomized to one of two approaches for providing support either lay-led group support or personalized computer-based support - to evaluate these strategies in enhancing longer-term maintenance of effects. Outcomes will include multiple CHD lifestyle behaviors (e.g., dietary intake, exercise levels, stress management, smoking cessation), physiological risk factors associated with CHD (e.g., serum lipids, hypertension, weight, vascular reactivity), HbA1c and quality of life (e.g., depression, functioning).

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Publications

Relative contributions of naturalistic and constructed support: two studies of women with type 2 diabetes.
Authors: Barrera M Jr, Toobert DJ, Strycker LA
Source: J Behav Med, 2014 Feb;37(1), p. 59-69.
PMID: 23109138
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Social-ecological resources as mediators of two-year diet and physical activity outcomes in type 2 diabetes patients.
Authors: Barrera M, Strycker LA, Mackinnon DP, Toobert DJ
Source: Health Psychol, 2008 Mar;27(2 Suppl), p. S118-25.
PMID: 18377153
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Social support and social-ecological resources as mediators of lifestyle intervention effects for type 2 diabetes.
Authors: Barrera M Jr, Toobert DJ, Angell KL, Glasgow RE, Mackinnon DP
Source: J Health Psychol, 2006 May;11(3), p. 483-95.
PMID: 16774900
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Effects of the mediterranean lifestyle program on multiple risk behaviors and psychosocial outcomes among women at risk for heart disease.
Authors: Toobert DJ, Strycker LA, Glasgow RE, Barrera Jr M, Angell K
Source: Ann Behav Med, 2005 Apr;29(2), p. 128-37.
PMID: 15823786
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The Chronic Illness Resources Survey: cross-validation and sensitivity to intervention.
Authors: Glasgow RE, Toobert DJ, Barrera M Jr, Strycker LA
Source: Health Educ Res, 2005 Aug;20(4), p. 402-9.
EPub date: 2004 Nov 30.
PMID: 15572438
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Biologic and quality-of-life outcomes from the Mediterranean Lifestyle Program: a randomized clinical trial.
Authors: Toobert DJ, Glasgow RE, Strycker LA, Barrera M Jr, Radcliffe JL, Wander RC, Bagdade JD
Source: Diabetes Care, 2003 Aug;26(8), p. 2288-93.
PMID: 12882850
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Enhancing support for health behavior change among women at risk for heart disease: the Mediterranean Lifestyle Trial.
Authors: Toobert DJ, Strycker LA, Glasgow RE, Barrera M, Bagdade JD
Source: Health Educ Res, 2002 Oct;17(5), p. 574-85.
PMID: 12408202
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Cardiovascular reactivity to mental stress in the Stockholm Female Coronary Risk Study.
Authors: Weidner G, Kohlmann CW, Horsten M, Wamala SP, Schenck-Gustafsson K, Högbom M, Orth-Gomer K
Source: Psychosom Med, 2001 Nov-Dec;63(6), p. 917-24.
PMID: 11719630
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