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Grant Details

Grant Number: 5R01CA081932-04 Interpret this number
Primary Investigator: Basch, Charles
Organization: Columbia University Teachers College
Project Title: Tailored Communications for Colorectal Cancer Screening
Fiscal Year: 2003
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Abstract

Recent health communications research using tailored messages, computer applications and interactive telephone outreach indicates that these approaches can effectively influence health-related behaviors, but very little research has attempted to apply these innovations to colorectal cancer (CRC) screening. Virtually no research of this type has been reported in minority populations. Screening for CRC has been shown to reduce CRC mortality, and current NCI guidelines recommend regular CRC screening for people aged 50 to 80 years. Yet the prevalence of CRC screening remains low, particularly in low-income and minority populations. The goal of the proposed study is to evaluate tailored health communications as a strategy for promoting CRC screening in a predominantly low-income minority population. The intervention, which will be delivered in Spanish as well as English, will be directed at a predominantly black and Hispanic population of men and women between 50-80 years of age who have not had CRC screening in at least the past two years. Participants will be sampled from the 1199 National Benefit Fund, the self-administered and self-insured health insurance and retirement benefit fund of the largest health care workers union in the U.S. The intervention comprises outreach and health communications provided through tailored telephone counseling coupled with computer-based decision support and tailored follow-up print communications. The proposed intervention strategy is a logical extension of recent research by Columbia University investigators and others, showing tailored health communications delivered by telephone to be an effective means of promoting screening behavior in low-income and minority populations. The study is designed as a randomized controlled trial with blinded ascertainment of medically documented CRC screening as the outcome. A total of 1,204 men and women will be randomized and followed to assess rates of fecal occult blood testing or flexible sigmoidoscopy within six months of randomization. This sample size will provide adequate statistical power to test the effect of the intervention separately in men and in women. Measures of mediating variables, including knowledge and beliefs, will be collected and used to formulate models predicting which subgroups are most and least likely to respond to the intervention. This proposal addresses the need for research assessing tailored communications to increase CRC screening in minority groups.

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Publications

Facilitating factors for colorectal cancer screening.
Authors: Brouse CH, Wolf RL, Basch CE
Source: J Cancer Educ, 2008 Jan-Mar;23(1), p. 26-31.
PMID: 18444043
Related Citations

Grant Numbers:
NCI NIH HHS - CA81932

MeSH Terms:
United States Humans Retrospective Studies
African Americans Health Services Accessibility Socioeconomic Factors
Mass Screening Health Status Indicators Patient Acceptance of Health Care
Poverty Health Knowledge, Attitudes, Practice Middle Aged
Colorectal Neoplasms Female Male

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Telephone outreach to increase colorectal cancer screening in an urban minority population.
Authors: Basch CE, Wolf RL, Brouse CH, Shmukler C, Neugut A, DeCarlo LT, Shea S
Source: Am J Public Health, 2006 Dec;96(12), p. 2246-53.
EPub date: 2006 Oct 31.
PMID: 17077394
Related Citations

Grant Numbers:
NCI NIH HHS - P30 CA13696 NCI NIH HHS - CA81932

MeSH Terms:
Occult Blood Telephone Humans
Outcome and Process Assessment (Health Care) African Americans Aged
Community-Institutional Relations Urban Health Services Socioeconomic Factors
Sigmoidoscopy Mass Screening New York City
Colonoscopy Minority Groups Patient Acceptance of Health Care
Middle Aged Postal Service Colorectal Neoplasms
Female Male

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Barriers to colorectal cancer screening: an educational diagnosis.
Authors: Brouse CH, Basch CE, Wolf RL, Shmukler C
Source: J Cancer Educ, 2004 Fall;19(3), p. 170-3.
PMID: 15458873
Related Citations

Grant Numbers:
NCI NIH HHS - CA81932

MeSH Terms:
Telephone Humans Aged
Health Education Health Services Accessibility New York City
Mass Screening Minority Groups Aged, 80 and over
Poverty Health Surveys Delivery of Health Care
Middle Aged Colorectal Neoplasms Female
Male

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Barriers to colorectal cancer screening with fecal occult blood testing in a predominantly minority urban population: a qualitative study.
Authors: Brouse CH, Basch CE, Wolf RL, Shmukler C, Neugut AI, Shea S
Source: Am J Public Health, 2003 Aug;93(8), p. 1268-71.
PMID: 12893609
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA81932 NCI NIH HHS - K05 CA89155 NCI NIH HHS - P30 CA13696 24

MeSH Terms:
United States Occult Blood Telephone
Humans Healthy People Programs Social Marketing
Aged Health Education Mass Screening
Labor Unions Minority Groups Patient Acceptance of Health Care
Health Personnel Middle Aged Urban Population
Colorectal Neoplasms Female Male

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Knowledge, beliefs, and barriers relevant to colorectal cancer screening in an urban population: a pilot study.
Authors: Wolf RL, Zybert P, Brouse CH, Neugut AI, Shea S, Gibson G, Lantigua RA, Basch CE
Source: Fam Community Health, 2001 Oct;24(3), p. 34-47.
PMID: 11563943
Related Citations

Grant Numbers:
NCI NIH HHS - KO5 CA89155 NCI NIH HHS - CA81932-01

MeSH Terms:
Humans Aged Pilot Projects
Demography New York City Patient Acceptance of Health Care
Health Knowledge, Attitudes, Practice Middle Aged Social Support
Urban Population Physician-Patient Relations Colorectal Neoplasms
Female Male

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.
Authors: Song WJ, Sullivan MG, Legare RD, Hutchings S, Tan X, Kufrin D, Ratajczak J, Resende IC, Haworth C, Hock R, Loh M, Felix C, Roy DC, Busque L, Kurnit D, Willman C, Gewirtz AM, Speck NA, Bushweller JH, Li FP, Gardiner K, Poncz M, Maris JM, Gilliland DG
Source: Nat Genet, 1999 Oct;23(2), p. 166-75.
PMID: 10508512
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA81932 NIAID NIH HHS - R29 AI39536 NCI NIH HHS - R01 CA78545

MeSH Terms:
Pedigree Sequence Homology, Nucleic Acid Humans
In Situ Hybridization, Fluorescence Leukemia, Myeloid, Acute Chromosome Mapping
Blood Platelets Thrombocytopenia Transcription Factors
Heterozygote Molecular Sequence Data Genetic Predisposition to Disease
Sequence Homology, Amino Acid Family Health Male
Sequence Deletion DNA-Binding Proteins DNA Mutational Analysis
Amino Acid Sequence Reverse Transcriptase Polymerase Chain Reaction Hematopoiesis
Genotype Microsatellite Repeats Base Sequence
Proto-Oncogene Proteins RNA Core Binding Factor Alpha 2 Subunit
Colony-Forming Units Assay Mutation Female
Megakaryocytes

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