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Grant Details

Grant Number: 5R01CA076330-05 Interpret this number
Primary Investigator: Vernon, Sally
Organization: University Of Texas Hlth Sci Ctr Houston
Project Title: Women Veterans and Breast Cancer Screening
Fiscal Year: 2003
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Abstract

We propose a 5-year prospective randomized trial of a theory-based intervention to increase compliance with mammography screening guidelines in female veterans 52 years of age and over. Specific aims of the project are to: 1) develop and evaluate the usefulness of an intervention based on the Transtheoretical Model (TTM) to increase compliance (completion of two mammograms) and coverage (completion of at least one mammogram) during the project; 2) analyze the relationship of a number of predictor variables with compliance and coverage; and 3) conduct a cost-effectiveness analysis of increasing compliance with mammography screening recommendations. We will randomly sample 7,500 women 52 years of age and over from the National Registry of Women Veterans (NRWV), a computerized database including 1.5 of the estimated 1.5-1.8 million women veterans separated from active military duty since January 1, 1942. Participants will be randomized to one of five groups. Groups 1 and 2 will be used to evaluate a targeted (aimed at an individual's stage of change) vs. a targeted and tailored (inclusion of personalized feedback) intervention. Groups 1 and 2 will receive an educational booklet based on the TTM. Group 1 also will receive a tailored feedback letter based on responses to a survey that measures constructs from the TTM (e.g., decisional balance, processes of change), as well as constructs from other behavior change models, while group 2 will receive a generic letter encouraging screening. There will be two rounds of the intervention for groups 1 and 2. Groups 3, 4, and 5 are control groups that will receive only the survey(s). Group 3 will be the primary control group against which we will measure the effect of the intervention; groups 4 and 5 will be used to evaluate secular trends and measurement effects of the surveys. Project materials will be mailed, and nonrespondents will be followed up by telephone. Mammography screening status will be ascertained by self-report, and a validation study will be conducted of the outcome measure. At this point, we know very little about how to get women to maintain regular mammography screening or about its cost-effectiveness. The few studies that have been conducted, or that are in progress, have focused on efficacy. The proposed research will evaluate the effectiveness of a sustained intervention to increase regular mammography in a nationally representative, well-defined population of women. The infrastructure is in place to institutionalize the intervention should it prove to be effective.

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Publications

Validation of a questionnaire to assess self-reported colorectal cancer screening status using face-to-face administration.
Authors: Fisher DA, Voils CI, Coffman CJ, Grubber JM, Dudley TK, Vernon SW, Bond JH, Provenzale D
Source: Dig Dis Sci, 2009 Jun;54(6), p. 1297-306.
EPub date: 2008 Aug 23.
PMID: 18726152
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Grant Numbers:
NCI NIH HHS - R01 CA97263 NCI NIH HHS - R21 CA102379-01A1 NCI NIH HHS - R21 CA102379
NIDDK NIH HHS - K24 DK002926 NCI NIH HHS - R01 CA76330 NCI NIH HHS - R21 CA102379-02

MeSH Terms:
Mass Screening Questionnaires Reproducibility of Results
Humans Health Behavior Aged
Middle Aged Male Female
Colorectal Neoplasms

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Promoting regular mammography screening II. Results from a randomized controlled trial in US women veterans.
Authors: Vernon SW, del Junco DJ, Tiro JA, Coan SP, Perz CA, Bastian LA, Rakowski W, Chan W, Lairson DR, McQueen A, Fernandez ME, Warrick C, Halder A, DiClemente C
Source: J Natl Cancer Inst, 2008 Mar 5;100(5), p. 347-58.
EPub date: 2008 Feb 26.
PMID: 18314474
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA076330-04S1 NCI NIH HHS - R25 CA057712 NCI NIH HHS - R03 CA103512-01A2
NCI NIH HHS - R01 CA76330 NCI NIH HHS - R03 CA103512-02 NCI NIH HHS - R01 CA076330-02S1
NCI NIH HHS - R01 CA076330-03S1 NCI NIH HHS - R01 CA076330-01A2 NCI NIH HHS - R01 CA076330-02
NCI NIH HHS - R03 CA 103512 NCI NIH HHS - R01 CA076330-03 NCI NIH HHS - R01 CA076330-04
NCI NIH HHS - R01 CA076330-05 NCI NIH HHS - R01 CA076330-05S2 NCI NIH HHS - KO7 CA79759
NCI NIH HHS - R01 CA076330-05S1

MeSH Terms:
United States Analysis of Variance Mammography
Reproducibility of Results Humans Aged
Breast Neoplasms Patient Selection Research Design
Veterans Registries Mass Screening
Logistic Models Patient Compliance Adult
Middle Aged Female Proportional Hazards Models

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Promoting regular mammography screening I. A systematic assessment of validity in a randomized trial.
Authors: del Junco DJ, Vernon SW, Coan SP, Tiro JA, Bastian LA, Savas LS, Perz CA, Lairson DR, Chan W, Warrick C, McQueen A, Rakowski W
Source: J Natl Cancer Inst, 2008 Mar 5;100(5), p. 333-46.
EPub date: 2008 Feb 26.
PMID: 18314473
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA076330-04S1 NCI NIH HHS - R03 CA103512-01A2 NCI NIH HHS - R01 CA76330
NCI NIH HHS - R03 CA103512-02 NCI NIH HHS - R01 CA076330-02S1 NCI NIH HHS - R01 CA076330-03S1
NCI NIH HHS - R01 CA076330-01A2 NCI NIH HHS - R01 CA076330-02 NCI NIH HHS - R03 CA 103512
NCI NIH HHS - R01 CA076330-03 NCI NIH HHS - R01 CA076330-04 NCI NIH HHS - R01 CA076330-05
NCI NIH HHS - R01 CA076330-05S2 NCI NIH HHS - R01 CA076330-05S1

MeSH Terms:
United States Mammography Reproducibility of Results
Humans Aged Breast Neoplasms
Patient Selection Research Design Registries
Veterans Mass Screening Middle Aged
Female

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Which women aren't getting mammograms and why? (United States).
Authors: Meissner HI, Breen N, Taubman ML, Vernon SW, Graubard BI
Source: Cancer Causes Control, 2007 Feb;18(1), p. 61-70.
PMID: 17186422
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA76330

MeSH Terms:
United States Mammography Questionnaires
Humans Breast Neoplasms Demography
Socioeconomic Factors Mass Screening Health Care Surveys
Patient Acceptance of Health Care Adult Middle Aged
Physician-Patient Relations Female

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Correlates of repeat and recent mammography for women ages 45 to 75 in the 2002 to 2003 Health Information National Trends Survey (HINTS 2003).
Authors: Rakowski W, Meissner H, Vernon SW, Breen N, Rimer B, Clark MA
Source: Cancer Epidemiol Biomarkers Prev, 2006 Nov;15(11), p. 2093-101.
PMID: 17119033
Related Citations

Grant Numbers:
NCI NIH HHS - K05-CA90485 NCI NIH HHS - R01-CA76330 NCI NIH HHS - R01-CA97263
NCI NIH HHS - R01-CA105486 NCI NIH HHS - K07-CA87070

MeSH Terms:
United States Odds Ratio Mammography
Reproducibility of Results Humans Aged
Breast Neoplasms Multivariate Analysis Mass Screening
Social Class Logistic Models Health Surveys
Middle Aged Female Prevalence

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Lessons learned from developing a tailored print intervention: a guide for practitioners and researchers new to tailoring.
Authors: Halder AK, Tiro JA, Glassman B, Rakowski W, Fernandez ME, Perez CA, Vernon SW
Source: Health Promot Pract, 2008 Jul;9(3), p. 281-8.
EPub date: 2006 Jul 7.
PMID: 16829660
Related Citations

Grant Numbers:
NCI NIH HHS - 1R01 CA76330-01A2

MeSH Terms:
Patient Education as Topic Mammography Humans
Reminder Systems Practice Guidelines as Topic Social Marketing
Pamphlets Female Health Promotion

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Validation of scales measuring attitudes and norms related to mammography screening in women veterans.
Authors: Tiro JA, Diamond PM, Perz CA, Fernandez M, Rakowski W, DiClemente CC, Vernon SW
Source: Health Psychol, 2005 Nov;24(6), p. 555-66.
PMID: 16287401
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA76330

MeSH Terms:
Mammography Questionnaires Attitude to Health
Reproducibility of Results Humans Breast Neoplasms
Veterans Demography Registries
Mass Screening Factor Analysis, Statistical Guidelines as Topic
Middle Aged Female

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Barriers to colorectal cancer screening: a comparison of reports from primary care physicians and average-risk adults.
Authors: Klabunde CN, Vernon SW, Nadel MR, Breen N, Seeff LC, Brown ML
Source: Med Care, 2005 Sep;43(9), p. 939-44.
PMID: 16116360
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA89475 NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA76330

MeSH Terms:
United States Diagnostic Tests, Routine Humans
Retrospective Studies Referral and Consultation Aged
Primary Health Care Communication Barriers Health Education
Mass Screening Health Care Surveys Aged, 80 and over
Logistic Models Middle Aged Physician's Practice Patterns
Colorectal Neoplasms Female Male

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Prevalence and correlates of repeat mammography among women aged 55-79 in the Year 2000 National Health Interview Survey.
Authors: Rakowski W, Breen N, Meissner H, Rimer BK, Vernon SW, Clark MA, Freedman AN
Source: Prev Med, 2004 Jul;39(1), p. 1-10.
PMID: 15207980
Related Citations

Grant Numbers:
NCI NIH HHS - K05-CA90485 NCI NIH HHS - R01-CA76330

MeSH Terms:
United States Educational Status Mammography
Women's Health Humans Aged
National Center for Health Statistics (U.S.) Income Logistic Models
Health Surveys Preventive Health Services Middle Aged
Female Prevalence

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Last Updated: August 24, 2012
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