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Grant Details

Grant Number: 5R01CA076330-05 Interpret this number
Primary Investigator: Vernon, Sally
Organization: University Of Texas Hlth Sci Ctr Houston
Project Title: Women Veterans and Breast Cancer Screening
Fiscal Year: 2003
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Abstract

We propose a 5-year prospective randomized trial of a theory-based intervention to increase compliance with mammography screening guidelines in female veterans 52 years of age and over. Specific aims of the project are to: 1) develop and evaluate the usefulness of an intervention based on the Transtheoretical Model (TTM) to increase compliance (completion of two mammograms) and coverage (completion of at least one mammogram) during the project; 2) analyze the relationship of a number of predictor variables with compliance and coverage; and 3) conduct a cost-effectiveness analysis of increasing compliance with mammography screening recommendations. We will randomly sample 7,500 women 52 years of age and over from the National Registry of Women Veterans (NRWV), a computerized database including 1.5 of the estimated 1.5-1.8 million women veterans separated from active military duty since January 1, 1942. Participants will be randomized to one of five groups. Groups 1 and 2 will be used to evaluate a targeted (aimed at an individual's stage of change) vs. a targeted and tailored (inclusion of personalized feedback) intervention. Groups 1 and 2 will receive an educational booklet based on the TTM. Group 1 also will receive a tailored feedback letter based on responses to a survey that measures constructs from the TTM (e.g., decisional balance, processes of change), as well as constructs from other behavior change models, while group 2 will receive a generic letter encouraging screening. There will be two rounds of the intervention for groups 1 and 2. Groups 3, 4, and 5 are control groups that will receive only the survey(s). Group 3 will be the primary control group against which we will measure the effect of the intervention; groups 4 and 5 will be used to evaluate secular trends and measurement effects of the surveys. Project materials will be mailed, and nonrespondents will be followed up by telephone. Mammography screening status will be ascertained by self-report, and a validation study will be conducted of the outcome measure. At this point, we know very little about how to get women to maintain regular mammography screening or about its cost-effectiveness. The few studies that have been conducted, or that are in progress, have focused on efficacy. The proposed research will evaluate the effectiveness of a sustained intervention to increase regular mammography in a nationally representative, well-defined population of women. The infrastructure is in place to institutionalize the intervention should it prove to be effective.

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Publications

Validation of a questionnaire to assess self-reported colorectal cancer screening status using face-to-face administration.
Authors: Fisher DA, Voils CI, Coffman CJ, Grubber JM, Dudley TK, Vernon SW, Bond JH, Provenzale D
Source: Dig Dis Sci, 2009 Jun;54(6), p. 1297-306.
EPub date: 2008 Aug 23.
PMID: 18726152
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Promoting regular mammography screening II. Results from a randomized controlled trial in US women veterans.
Authors: Vernon SW, del Junco DJ, Tiro JA, Coan SP, Perz CA, Bastian LA, Rakowski W, Chan W, Lairson DR, McQueen A, Fernandez ME, Warrick C, Halder A, DiClemente C
Source: J Natl Cancer Inst, 2008 Mar 5;100(5), p. 347-58.
EPub date: 2008 Feb 26.
PMID: 18314474
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Promoting regular mammography screening I. A systematic assessment of validity in a randomized trial.
Authors: del Junco DJ, Vernon SW, Coan SP, Tiro JA, Bastian LA, Savas LS, Perz CA, Lairson DR, Chan W, Warrick C, McQueen A, Rakowski W
Source: J Natl Cancer Inst, 2008 Mar 5;100(5), p. 333-46.
EPub date: 2008 Feb 26.
PMID: 18314473
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Which women aren't getting mammograms and why? (United States).
Authors: Meissner HI, Breen N, Taubman ML, Vernon SW, Graubard BI
Source: Cancer Causes Control, 2007 Feb;18(1), p. 61-70.
PMID: 17186422
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Correlates of repeat and recent mammography for women ages 45 to 75 in the 2002 to 2003 Health Information National Trends Survey (HINTS 2003).
Authors: Rakowski W, Meissner H, Vernon SW, Breen N, Rimer B, Clark MA
Source: Cancer Epidemiol Biomarkers Prev, 2006 Nov;15(11), p. 2093-101.
PMID: 17119033
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Lessons learned from developing a tailored print intervention: a guide for practitioners and researchers new to tailoring.
Authors: Halder AK, Tiro JA, Glassman B, Rakowski W, Fernandez ME, Perez CA, Vernon SW
Source: Health Promot Pract, 2008 Jul;9(3), p. 281-8.
EPub date: 2006 Jul 7.
PMID: 16829660
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Validation of scales measuring attitudes and norms related to mammography screening in women veterans.
Authors: Tiro JA, Diamond PM, Perz CA, Fernandez M, Rakowski W, DiClemente CC, Vernon SW
Source: Health Psychol, 2005 Nov;24(6), p. 555-66.
PMID: 16287401
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Barriers to colorectal cancer screening: a comparison of reports from primary care physicians and average-risk adults.
Authors: Klabunde CN, Vernon SW, Nadel MR, Breen N, Seeff LC, Brown ML
Source: Med Care, 2005 Sep;43(9), p. 939-44.
PMID: 16116360
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Prevalence and correlates of repeat mammography among women aged 55-79 in the Year 2000 National Health Interview Survey.
Authors: Rakowski W, Breen N, Meissner H, Rimer BK, Vernon SW, Clark MA, Freedman AN
Source: Prev Med, 2004 Jul;39(1), p. 1-10.
PMID: 15207980
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