||5R21CA090904-02 Interpret this number
||Fox Chase Cancer Center
||A Multimedia Prostate Cancer Intelligent Expert System
DESCRIPTION (provided by investigator): Patients diagnosed with early-stage
prostate cancer not only have to adjust to the psychosocial and physical
consequences of their disease, but also must make sense of often complex and
probabilistic information about their condition and treatment options. Yet,
surprisingly, there are few structured and effective programs available to
inform patients about their treatment options and to assist them in their
treatment decision. We propose to develop and evaluate a computer-based
multimedia intelligent expert system, designed to inform patients diagnosed
with early stage prostate cancer about the disease, their treatment options,
and about potential treatment consequences. The Prostate Intelligent Expert
System (PIES) will present disease and treatment information that is targeted
to the patient?s ethnicity and age, and tailored to his information seeking
preference. The development of the program is guided by a cognitive-social
approach to health information processing, which postulates that cognitive
factors (i.e., expectations and beliefs about the disease and its treatment)
and affective factors (i.e., cancer related worry) influence information
processing and decision-making. From a technical point of view PIES is based on
a successful multimedia intelligent expert instructional program to teach
undergraduate courses in electrical engineering. The expert system goes beyond
the common "if. then" statements used to tailor information to patients. Rather
it continuously monitors the patient?s interaction with PIES, and thus is able
to tailor information closely to the patients needs.
PIES simulates a virtual health center. The patient can explore different
virtual rooms (e.g., the library, the physician?s office, a support group, etc)
to obtain information in an interactive way. Information will be presented
through text, video, audio, and animation. The intelligent expert system will
adjust the level of complexity of the information to meet the patient?s
observed and stated information seeking preference.
The feasibility and usability of PIES will be evaluated throughout the
development period by the consulting physicians and by members of the target
audience through focus groups and individual sessions during which patients
explore earlier versions of the program. Formal usability and feasibility
testing will be performed with early-stage prostate cancer patients (N=90)
using a within-subject design. Assessments about prostate cancer knowledge and
distress about treatment decision making will be obtained prior to and after
completing PIES. Six weeks later patients? (N=81) treatment choice will be
assessed. It is expected that PIES will result in an increase in disease and
treatment knowledge, high satisfaction ratings with the information provided,
and that PIES will facilitate treatment decision making.
Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study.
Diefenbach MA, Mohamed NE, Butz BP, Bar-Chama N, Stock R, Cesaretti J, Hassan W, Samadi D, Hall SJ
J Med Internet Res, 2012 Jan 13;14(1), p. e6.
2012 Jan 13.
NCI NIH HHS - CA6136-05
NCI NIH HHS - CA90904-02
A multimedia interactive education system for prostate cancer patients: development and preliminary evaluation.
Diefenbach MA, Butz BP
J Med Internet Res, 2004 Jan 21;6(1), p. e3.
2004 Jan 21.