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National Institutes of Health: National Cancer Institute: Division of Cancer Control and Population Sciences
Grant Details

Grant Number: 5R01HL062156-04 Interpret this number
Primary Investigator: Toobert, Deborah
Organization: Oregon Research Institute
Project Title: Enhancing Support for Women at Risk for Heart Disease
Fiscal Year: 2002
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Abstract

ABSTRACT=The overall goal of this project is to test a practical, theory- based intervention to achieve long-term behavior change for women with Type 2 diabetes at high risk for developing coronary heart disease (CHD). Epidemiological and clinical studies suggest that diabetes is associated with increased risk for CHD that is greater in women than in men. CHD is a major cause of death and functional limitations in women, but the vast majority of CHD studies have primarily involved middle-aged men. There is convincing research evidence that healthy lifestyle behaviors, including low-fat diet, physical activity, stress management, smoking cessation, and social support, can reduce CHD risk. We will conduct a randomized trial to compare short-term (6-month) outcomes in women receiving usual care compared to a modified Ornish-type comprehensive lifestyle management (CLM) intervention. After 6 months, women in the CLM condition will be randomized to one of two approaches for providing support either lay-led group support or personalized computer-based support - to evaluate these strategies in enhancing longer-term maintenance of effects. Outcomes will include multiple CHD lifestyle behaviors (e.g., dietary intake, exercise levels, stress management, smoking cessation), physiological risk factors associated with CHD (e.g., serum lipids, hypertension, weight, vascular reactivity), HbA1c and quality of life (e.g., depression, functioning).

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Publications

Cardiovascular Reactivity To Mental Stress In The Stockholm Female Coronary Risk Study
Authors: Weidner G. , Kohlmann C.W. , Horsten M. , Wamala S.P. , Schenck-Gustafsson K. , Högbom M. , Orth-Gomer K. .
Source: Psychosomatic Medicine, 2001 Nov-Dec; 63(6), p. 917-24.
PMID: 11719630
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Enhancing Support For Health Behavior Change Among Women At Risk For Heart Disease: The Mediterranean Lifestyle Trial
Authors: Toobert D.J. , Strycker L.A. , Glasgow R.E. , Barrera M. , Bagdade J.D. .
Source: Health Education Research, 2002 Oct; 17(5), p. 574-85.
PMID: 12408202
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Biologic And Quality-of-life Outcomes From The Mediterranean Lifestyle Program: A Randomized Clinical Trial
Authors: Toobert D.J. , Glasgow R.E. , Strycker L.A. , Barrera M. , Radcliffe J.L. , Wander R.C. , Bagdade J.D. .
Source: Diabetes Care, 2003 Aug; 26(8), p. 2288-93.
PMID: 12882850
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The Chronic Illness Resources Survey: Cross-validation And Sensitivity To Intervention
Authors: Glasgow R.E. , Toobert D.J. , Barrera M. , Strycker L.A. .
Source: Health Education Research, 2005 Aug; 20(4), p. 402-9.
PMID: 15572438
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Effects Of The Mediterranean Lifestyle Program On Multiple Risk Behaviors And Psychosocial Outcomes Among Women At Risk For Heart Disease
Authors: Toobert D.J. , Strycker L.A. , Glasgow R.E. , Barrera Jr M. , Angell K. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2005 Apr; 29(2), p. 128-37.
PMID: 15823786
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Social Support And Social-ecological Resources As Mediators Of Lifestyle Intervention Effects For Type 2 Diabetes
Authors: Barrera M. , Toobert D.J. , Angell K.L. , Glasgow R.E. , Mackinnon D.P. .
Source: Journal Of Health Psychology, 2006 May; 11(3), p. 483-95.
PMID: 16774900
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Social-ecological Resources As Mediators Of Two-year Diet And Physical Activity Outcomes In Type 2 Diabetes Patients
Authors: Barrera M. , Strycker L.A. , Mackinnon D.P. , Toobert D.J. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2008 Mar; 27(2 Suppl), p. S118-25.
PMID: 18377153
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Relative Contributions Of Naturalistic And Constructed Support: Two Studies Of Women With Type 2 Diabetes
Authors: Barrera M. , Toobert D.J. , Strycker L.A. .
Source: Journal Of Behavioral Medicine, 2014 Feb; 37(1), p. 59-69.
PMID: 23109138
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