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Grant Details

Grant Number: 5R21CA088293-02 Interpret this number
Primary Investigator: Lutgendorf, Susan
Organization: University Of Iowa
Project Title: Biobehavioral Immune Interactions in Ovarian Cancer
Fiscal Year: 2001
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Abstract

An abstract does not currently exist for this grant

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Publications

Social influences on clinical outcomes of patients with ovarian cancer.
Authors: Lutgendorf SK, De Geest K, Bender D, Ahmed A, Goodheart MJ, Dahmoush L, Zimmerman MB, Penedo FJ, Lucci JA 3rd, Ganjei-Azar P, Thaker PH, Mendez L, Lubaroff DM, Slavich GM, Cole SW, Sood AK
Source: J Clin Oncol, 2012 Aug 10;30(23), p. 2885-90.
EPub date: 2012 Jul 16.
PMID: 22802321
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA140933 NCI NIH HHS - CA88293 NCI NIH HHS - CA109298
NCI NIH HHS - R01 CA104825 NCI NIH HHS - CA140933 NCI NIH HHS - CA104825
NCI NIH HHS - P50CA083639 NCI NIH HHS - CA116778

MeSH Terms:
Prospective Studies Ovarian Neoplasms Humans
Aged Social Support Outcome Assessment (Health Care)
Middle Aged Female Proportional Hazards Models
Neoplasms, Glandular and Epithelial

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Biobehavioral factors and cancer progression: physiological pathways and mechanisms.
Authors: Lutgendorf SK, Sood AK
Source: Psychosom Med, 2011 Nov-Dec;73(9), p. 724-30.
EPub date: 2011 Oct 21.
PMID: 22021459
Related Citations

Grant Numbers:
NCI NIH HHS - CA88293 NCI NIH HHS - CA109298 NCI NIH HHS - CA110793
NCI NIH HHS - CA140933 NCI NIH HHS - CA104825 NCI NIH HHS - R01 CA140933-04
NCI NIH HHS - R01 CA140933-03 NCI NIH HHS - P50 CA083639

MeSH Terms:
Animals Anoikis Depression
Hypothalamo-Hypophyseal System Humans Tumor Microenvironment
Disease Progression Survival Disease Models, Animal
Inflammation Pituitary-Adrenal System Neoplasms
Neoplastic Processes Immunity, Cellular Down-Regulation
Risk Factors Stress, Psychological Social Isolation
Neovascularization, Pathologic

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Social isolation is associated with elevated tumor norepinephrine in ovarian carcinoma patients.
Authors: Lutgendorf SK, DeGeest K, Dahmoush L, Farley D, Penedo F, Bender D, Goodheart M, Buekers TE, Mendez L, Krueger G, Clevenger L, Lubaroff DM, Sood AK, Cole SW
Source: Brain Behav Immun, 2011 Feb;25(2), p. 250-5.
EPub date: 2010 Oct 16.
PMID: 20955777
Related Citations

Grant Numbers:
NCI NIH HHS - CA110793 NCI NIH HHS - R01 CA104825-02S1 NCI NIH HHS - R01 CA116778-01A2
NCI NIH HHS - R21 CA088293-01 NCI NIH HHS - R01 CA110793-01 NCI NIH HHS - CA109298
NCI NIH HHS - CA88293 NCI NIH HHS - R01 CA104825-01 NCI NIH HHS - CA140933
NCI NIH HHS - CA104825 NCI NIH HHS - R01 CA109298-01A1 NCI NIH HHS - R01 CA140933-01
NCI NIH HHS - R01 CA140933-03 NCI NIH HHS - P50CA083639 NCI NIH HHS - CA116778

MeSH Terms:
Young Adult Depression Ovarian Neoplasms
Humans Aged Socioeconomic Factors
Catecholamines Stress, Psychological Adult
Norepinephrine Health Behavior Middle Aged
Social Support Social Isolation Female

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Care of the caregiver: stress and dysregulation of inflammatory control in cancer caregivers.
Authors: Lutgendorf SK, Laudenslager ML
Source: J Clin Oncol, 2009 Jun 20;27(18), p. 2894-5.
EPub date: 2009 May 11.
PMID: 19433678
Related Citations

Grant Numbers:
NCI NIH HHS - CA88293 NCI NIH HHS - R01 CA140933-02 NCI NIH HHS - CA104825
NCI NIH HHS - CA12967

MeSH Terms:
Neoplasms Caregivers Humans
Stress, Psychological Inflammation

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Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma.
Authors: Lutgendorf SK, Lamkin DM, Jennings NB, Arevalo JM, Penedo F, DeGeest K, Langley RR, Lucci JA 3rd, Cole SW, Lubaroff DM, Sood AK
Source: Clin Cancer Res, 2008 Nov 1;14(21), p. 6839-46.
PMID: 18980978
Related Citations

Grant Numbers:
NCI NIH HHS - CA110793 NCI NIH HHS - R01 CA104825-02S1 NCI NIH HHS - R01 CA109298-05
NCI NIH HHS - R01 CA109298-04 NCI NIH HHS - R01 CA110793-01 NCI NIH HHS - R01 CA110793-04
NCI NIH HHS - CA109298 NCI NIH HHS - CA88293 NCI NIH HHS - R01 CA109298-02
NCI NIH HHS - R01 CA110793-05 NCI NIH HHS - R01 CA104825-01 NCI NIH HHS - R01 CA109298-03
NCI NIH HHS - R01 CA110793-02 NCI NIH HHS - R01 CA110793-03 NCI NIH HHS - R01 CA104825-03S2
NCI NIH HHS - CA104825 NCI NIH HHS - R01 CA109298-01A1 NCI NIH HHS - P50CA083639

MeSH Terms:
Macrophages Ovarian Neoplasms Depression
Hydrocortisone Humans Aged
Matrix Metalloproteinases Behavior Aged, 80 and over
Stress, Psychological Adult Norepinephrine
Mood Disorders Social Support Middle Aged
Female

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Interleukin-6, cortisol, and depressive symptoms in ovarian cancer patients.
Authors: Lutgendorf SK, Weinrib AZ, Penedo F, Russell D, DeGeest K, Costanzo ES, Henderson PJ, Sephton SE, Rohleder N, Lucci JA 3rd, Cole S, Sood AK, Lubaroff DM
Source: J Clin Oncol, 2008 Oct 10;26(29), p. 4820-7.
EPub date: 2008 Sep 8.
PMID: 18779606
Related Citations

Grant Numbers:
NCI NIH HHS - CA88293 NCI NIH HHS - CA104825

MeSH Terms:
Depression Hydrocortisone Ovarian Neoplasms
Humans Aged Circadian Rhythm
Aged, 80 and over Adult Interleukin-6
Middle Aged Biological Markers Female
Neoplasms, Glandular and Epithelial

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Depression, social support, and beta-adrenergic transcription control in human ovarian cancer.
Authors: Lutgendorf SK, DeGeest K, Sung CY, Arevalo JM, Penedo F, Lucci J 3rd, Goodheart M, Lubaroff D, Farley DM, Sood AK, Cole SW
Source: Brain Behav Immun, 2009 Feb;23(2), p. 176-83.
EPub date: 2008 Jun 11.
PMID: 18550328
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA88293 NCI NIH HHS - R01 CA110793-05 NCI NIH HHS - R01 CA104825
NCI NIH HHS - R01 CA109298 NCI NIH HHS - R01 CA116778-02 NCI NIH HHS - R01 CA116778-01A2
NCI NIH HHS - R01 CA110793 NCI NIH HHS - R01 CA109298-05 NCI NIH HHS - R01 CA116778
NCI NIH HHS - R01 CA116778-03

MeSH Terms:
NF-kappa B Ovarian Neoplasms Depression
Oligonucleotide Array Sequence Analysis Humans Activating Transcription Factors
Aged Transcription, Genetic Reverse Transcriptase Polymerase Chain Reaction
Cyclic AMP Response Element-Binding Protein Chromatography, High Pressure Liquid Gene Expression Regulation, Neoplastic
Neoplasms Aged, 80 and over Risk Factors
Norepinephrine Adult Social Support
Middle Aged Female

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Social support, psychological distress, and natural killer cell activity in ovarian cancer.
Authors: Lutgendorf SK, Sood AK, Anderson B, McGinn S, Maiseri H, Dao M, Sorosky JI, De Geest K, Ritchie J, Lubaroff DM
Source: J Clin Oncol, 2005 Oct 1;23(28), p. 7105-13.
PMID: 16192594
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA88293 NCI NIH HHS - R01-CA1045-25

MeSH Terms:
Ovarian Neoplasms Humans Aged
Lymphocytes, Tumor-Infiltrating Ascites Killer Cells, Natural
Adult Stress, Psychological Case-Control Studies
Middle Aged Social Support Monocytes
Female

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Quality of life and mental health in cervical and endometrial cancer survivors.
Authors: Bradley S, Rose S, Lutgendorf S, Costanzo E, Anderson B
Source: Gynecol Oncol, 2006 Mar;100(3), p. 479-86.
EPub date: 2005 Sep 26.
PMID: 16185753
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA88293 NCI NIH HHS - R01CA1045-25

MeSH Terms:
Uterine Cervical Neoplasms Endometrial Neoplasms Humans
Quality of Life Aged Middle Aged
Mental Health Affect Female

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Psychosocial factors and interleukin-6 among women with advanced ovarian cancer.
Authors: Costanzo ES, Lutgendorf SK, Sood AK, Anderson B, Sorosky J, Lubaroff DM
Source: Cancer, 2005 Jul 15;104(2), p. 305-13.
PMID: 15954082
Related Citations

Grant Numbers:
NCI NIH HHS - 1R21 CA88293 NCI NIH HHS - R01 CA104525 NIA NIH HHS - T32 AG 00214

MeSH Terms:
Ovarian Neoplasms Depression Psychology
Ascitic Fluid Humans Quality of Life
Interleukin-6 Social Support Middle Aged
Female Stress, Physiological

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Mood and cytokine response to influenza virus in older adults.
Authors: Costanzo ES, Lutgendorf SK, Kohut ML, Nisly N, Rozeboom K, Spooner S, Benda J, McElhaney JE
Source: J Gerontol A Biol Sci Med Sci, 2004 Dec;59(12), p. 1328-33.
PMID: 15699534
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA88293-01

MeSH Terms:
Interleukin-10 Interferon-gamma Humans
Aged Th2 Cells Orthomyxoviridae
Aged, 80 and over Interleukin-2 Mood Disorders
Cytokines Female Influenza Vaccines
Male Th1 Cells

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Vascular endothelial growth factor and social support in patients with ovarian carcinoma.
Authors: Lutgendorf SK, Johnsen EL, Cooper B, Anderson B, Sorosky JI, Buller RE, Sood AK
Source: Cancer, 2002 Aug 15;95(4), p. 808-15.
PMID: 12209725
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA88293

MeSH Terms:
Vascular Endothelial Growth Factor A Depression Ovarian Neoplasms
Humans Aged Quality of Life
Endothelial Growth Factors Carcinoma Vascular Endothelial Growth Factors
Adult Middle Aged Social Support
Lymphokines Female

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Last Updated: August 24, 2012
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