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Grant Details

Grant Number: 5R01CA023225-06 Interpret this number
Primary Investigator: Savarese, Todd
Organization: Roger Williams Hospital
Project Title: Differentiation-Induction in Human Colon Cancer Cells
Fiscal Year: 1984
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Abstract

An abstract does not currently exist for this grant

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Publications

Role of glutathione depletion in the mechanism of action of N-methylformamide and N,N-dimethylformamide in a cultured human colon carcinoma cell line.
Authors: Cordeiro RF, Savarese TM
Source: Cancer Res, 1986 Mar;46(3), p. 1297-305.
PMID: 3943098
Related Citations

Grant Numbers:
NCI NIH HHS - CA13943 NCI NIH HHS - CA38630 NCI NIH HHS - CA23225

MeSH Terms:
Dose-Response Relationship, Drug Glutathione Humans
Buthionine Sulfoximine Solvents Methionine Sulfoximine
Cisplatin Cysteine Cell Cycle
Colonic Neoplasms Cell Line Dimethylformamide
Formamides

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Enhancement by N-methylformamide of the effect of ionizing radiation on a human colon tumor xenografted in nude mice.
Authors: Dexter DL, Lee ES, Bliven SF, Glicksman AS, Leith JT
Source: Cancer Res, 1984 Nov;44(11), p. 4942-6.
PMID: 6488157
Related Citations

Grant Numbers:
NCI NIH HHS - CA25687 NCI NIH HHS - CA13943 NCI NIH HHS - CA23225

MeSH Terms:
Animals Antineoplastic Agents Combined Modality Therapy
Humans Mice Mice, Nude
Cell Survival Neoplasm Transplantation Transplantation, Heterologous
Colonic Neoplasms Cell Line Formamides
Cell Division

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Reversal by L-cysteine of the growth inhibitory and glutathione-depleting effects of N-methylformamide and N,N-dimethylformamide.
Authors: Cordeiro RF, Savarese TM
Source: Biochem Biophys Res Commun, 1984 Jul 31;122(2), p. 798-803.
PMID: 6466338
Related Citations

Grant Numbers:
NCI NIH HHS - CA23225

MeSH Terms:
Clone Cells Glutathione Cysteine
Antineoplastic Agents Humans Drug Antagonism
Colonic Neoplasms Formamides Dimethylformamide
Cell Line Cell Survival Cell Division

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Sodium butyrate-induced alteration of growth properties and glycogen levels in cultured human colon carcinoma cells.
Authors: Dexter DL, Lev R, McKendall GR, Mitchell P, Calabres P
Source: Histochem J, 1984 Feb;16(2), p. 137-49.
PMID: 6698802
Related Citations

Grant Numbers:
NCI NIH HHS - CA13943 NCI NIH HHS - CA23225 NCI NIH HHS - CA20892

MeSH Terms:
Clone Cells Butyric Acid Humans
Butyrates Colonic Neoplasms Glycogen
Cell Line

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Human tumor cell heterogeneity and metastasis.
Authors: Spremulli EN, Dexter DL
Source: J Clin Oncol, 1983 Aug;1(8), p. 496-509.
PMID: 6366142
Related Citations

Grant Numbers:
NCI NIH HHS - CA26218 NCI NIH HHS - CA23225

MeSH Terms:
Animals Neoplasms Lymphatic Metastasis
Lung Neoplasms Humans Neoplasm Metastasis
Antigens, Neoplasm Mice Colonic Neoplasms
Neoplastic Cells, Circulating Cell Division

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Intraneoplastic diversity.
Authors: Dexter DL, Calabresi P
Source: Biochim Biophys Acta, 1982 Dec 21;695(2), p. 97-112.
PMID: 6763878
Related Citations

Grant Numbers:
NCI NIH HHS - CA13943 NCI NIH HHS - CA23225 NCI NIH HHS - CA20892

MeSH Terms:
Karyotyping Animals Neoplasms
Humans Neoplasm Metastasis Cell Differentiation
Drug Evaluation, Preclinical Neoplasms, Experimental

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Heterogeneity of cancer cells from a single human colon carcinoma.
Authors: Dexter DL, Spremulli EN, Fligiel Z, Barbosa JA, Vogel R, VanVoorhees A, Calabresi P
Source: Am J Med, 1981 Dec;71(6), p. 949-56.
PMID: 7315857
Related Citations

Grant Numbers:
NCI NIH HHS - CA13943 NCI NIH HHS - CA23225 NCI NIH HHS - CA20892

MeSH Terms:
Clone Cells Karyotyping Animals
Antineoplastic Agents Humans Mice, Nude
Mice Cell Survival Phenotype
Neoplasm Transplantation Cells, Cultured Adenocarcinoma
Colonic Neoplasms Drug Evaluation, Preclinical Cell Line
Male

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