Grant Details
Grant Number: |
1R43CA079331-01 Interpret this number |
Primary Investigator: |
Schimert, James |
Organization: |
Insightful Corporation |
Project Title: |
Tree Based Software for Biomedical Applications |
Fiscal Year: |
1998 |
Abstract
We propose to develop software for tree-based methods which implements
research on biomedical applications not currently supported by
commercial software. Examples include survival and longitudinal data
analysis, generalized tree models, and clustering. Tree-based tools
offer many advantages including easy interpretation since tree
representations may mimic the way that many medical scientists think
about data.
Phase I research will focus on (1) analyzing user and software
requirements, (2) creating an object-oriented design, (3) implementing
this design for clustering and survival analysis, and researching the
practical issues of (4) handling missing values using multiple
imputation and (5) creating diagnostics for tree stability using the
bootstrap. In Phase II, we will complete the coding and testing of
software for survival analysis and clustering applications, and
develop code for longitudinal data analysis and generalized tree
models.
We will create software that analysts find flexible and easy to use,
enabling medical researchers to use tree-based tools to explore and
understand data from a wide variety of applications. Additionally,
the software will be supported in an integrated environment for data
analysis, and permit analysts, consultants, and statistical
researchers to extend the software to incorporate future innovations
in recursive partitioning research.
PROPOSED COMMERCIAL APPLICATIONS:
This SBIR will result in a new software package which is inter-
operable with existing S-Plus products. We expect this product to
appeal to a wide market of users including data analysts, consultants,
and researchers in disciplines as diverse as medicine, pattern
recognition, data mining, and image analysis.
Publications
None