Grant Details
| Grant Number: | 1R43CA078093-01 Interpret this number |
| Primary Investigator: | Schwartz, Stanley |
| Organization: | Chi Systems, Inc. |
| Project Title: | New Health Assessment Methods for Cancer Prevention |
| Fiscal Year: | 1998 |
Abstract
DESCRIPTION: The proposed research enhances dissemination of cancer prevention, screening, and assessment (P/S/A) information through a dissemination model termed 'physician-directed, customized delivery.' Current methods of disseminating cancer prevention information rely on 'broadcast' mechanisms. Evaluative studies, however suggest that more effective dissemination occurs when information is 'narrowcast,' i.e., directed at a patient specifically, and done in the context of encouragement from a specific medical source (e.g., personal physician). although this dissemination model suggests an increased role for the primary care physician, current trends toward reduced patient/physician interaction mitigate against its manual implementation. To remedy this, CHI Systems proposes an automated system, called the Patient Intake and Recommendations Tool (PIRT), which will automate the taking of patient histories and map the resulting patient specific data onto customized P/S/A recommendations. Using expert systems technology developed by the Principal Investigator to tailor P/S/A guidelines to the patient's individual characteristics, PIRT will also support primary care providers in dissemination this information to patients and tracking compliance. The Phase I research aims to design and establish the feasibility of building a full-scale PIRT prototype. Phase II would build the prototype and include a field evaluation of the prototype and of the underlying physician-directed, customized delivery model.
Publications
Identifying actives from HTS data sets: practical approaches for the selection of an appropriate HTS data-processing method and quality control review.
Authors: Shun T.Y. , Lazo J.S. , Sharlow E.R. , Johnston P.A. .
Source: Journal of biomolecular screening, 2011 Jan; 16(1), p. 1-14.
EPub date: 2010-12-15.
PMID: 21160066
Related Citations
Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library.
Authors: Johnston P.A. , Foster C.A. , Tierno M.B. , Shun T.Y. , Shinde S.N. , Paquette W.D. , Brummond K.M. , Wipf P. , Lazo J.S. .
Source: Assay and drug development technologies, 2009 Jun; 7(3), p. 250-65.
PMID: 19530895
Related Citations