Skip Navigation
Grant Details

Grant Number: 3P50CA148596-04S1 Interpret this number
Primary Investigator: Williams, David
Organization: Harvard College
Project Title: Lung Cancer Disparities Center: Jointly Addressing Race & Socioeconomic Status
Fiscal Year: 2013
Back to top


Abstract

DESCRIPTION (provided by applicant): The Lung Cancer Disparities Center will be an interdisciplinary center for research (including community based participatory research), core support and dissemination activities focused on understanding and altering the determinants of racial/ethnic and socioeconomic status (SES) disparities along the continuum of lung cancer. Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations; without cigarette smoking, lung cancer would be rare. Thus, identifying effective strategies to prevent the initiation of smoking and facilitate cessation among smokers is critical to reducing the risk of lung cancer. We also need to better understand the contribution of the social environment to the onset, course, and outcomes of lung cancer. The five projects and cores have the following specific aims: 1) develop and test novel tobacco control interventions that address the social context that initiate and sustain smoking behavior; 2) develop and apply sophisticated concepts, measures, and methods regarding community-focused research to all of the activities of Center; 3) draw on the expertise of a multidisciplinary team of researchers to bring a social determinants perspective to the clinical factors and other individual level factors that lead to social disparities in lung cancer survival and the genetic factors that could affect the onset, course and outcomes of lung cancer; 4) refine existing conceptual and methodological approaches to understanding and describing the joint contribution of race/ethnicity and SES to lung cancer; 5) develop a strong and cutting-edge training program to train the population health investigators of the future; and 6) fund highly innovative and high-risk pilot projects to inform research and application concerned with jointly understanding race/ethnicity and SES to disparities in lung cancer and its determinants. Significantly, this work will be accomplished by a transdisciplinary team of researchers who have made seminal contributions to population health and health disparities, in an institutional environment in which there is substantial intellectual and financial support for such an interdisciplinary Center. RELEVANCE: The Center on Lung Cancer Disparities will identify how environmental conditions - related to race/ethnicity and patterns of risk produce social disparities in lung cancer outcomes by influencing multiple pathways leading to poor health. Our Center focuses on one specific condition (lung cancer) and its key behavioral determinant (cigarette smoking). Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations; without cigarette smoking, lung cancer would be rare.

Back to top


Publications

Effect of graphic cigarette warnings on smoking intentions in young adults.
Authors: Blanton H, Snyder LB, Strauts E, Larson JG
Source: PLoS One, 2014;9(5), p. e96315.
EPub date: 2014 May 7.
PMID: 24806481
Related Citations

Back to top


Demographic disparities in the tobacco retail environment in Boston: a citywide spatial analysis.
Authors: Duncan DT, Kawachi I, Melly SJ, Blossom J, Sorensen G, Williams DR
Source: Public Health Rep, 2014 Mar-Apr;129(2), p. 209-15.
PMID: 24587559
Related Citations

Back to top


Discrimination, other psychosocial stressors, and self-reported sleep duration and difficulties.
Authors: Slopen N, Williams DR
Source: Sleep, 2014 Jan 1;37(1), p. 147-56.
EPub date: 2014 Jan 1.
PMID: 24381373
Related Citations

Back to top


Racism and Health II: A Needed Research Agenda for Effective Interventions.
Authors: Williams DR, Mohammed SA
Source: Am Behav Sci, 2013 Aug 1;57(8), p. null.
PMID: 24347667
Related Citations

Back to top


Racism and Health I: Pathways and Scientific Evidence.
Authors: Williams DR, Mohammed SA
Source: Am Behav Sci, 2013 Aug 1;57(8), p. null.
PMID: 24347666
Related Citations

Back to top


Mental health service use from a religious or spiritual advisor among Asian Americans.
Authors: John DA, Williams DR
Source: Asian J Psychiatr, 2013 Dec;6(6), p. 599-605.
EPub date: 2013 May 23.
PMID: 24309881
Related Citations

Back to top


Examination of how neighborhood definition influences measurements of youths' access to tobacco retailers: a methodological note on spatial misclassification.
Authors: Duncan DT, Kawachi I, Subramanian SV, Aldstadt J, Melly SJ, Williams DR
Source: Am J Epidemiol, 2014 Feb 1;179(3), p. 373-81.
EPub date: 2013 Oct 22.
PMID: 24148710
Related Citations

Back to top


Psychosocial stress and cigarette smoking persistence, cessation, and relapse over 9-10 years: a prospective study of middle-aged adults in the United States.
Authors: Slopen N, Kontos EZ, Ryff CD, Ayanian JZ, Albert MA, Williams DR
Source: Cancer Causes Control, 2013 Oct;24(10), p. 1849-63.
EPub date: 2013 Jul 17.
PMID: 23860953
Related Citations

Back to top


Use of practice-based research network data to measure neighborhood smoking prevalence.
Authors: Linder JA, Rigotti NA, Brawarsky P, Kontos EZ, Park ER, Klinger EV, Marinacci L, Li W, Haas JS
Source: Prev Chronic Dis, 2013 May 23;10, p. E84.
EPub date: 2013 May 23.
PMID: 23701721
Related Citations

Back to top


Implementation and research priorities for FCTC Articles 13 and 16: tobacco advertising, promotion, and sponsorship and sales to and by minors.
Authors: Nagler RH, Viswanath K
Source: Nicotine Tob Res, 2013 Apr;15(4), p. 832-46.
EPub date: 2013 Jan 4.
PMID: 23291641
Related Citations

Back to top


Miles to go before we sleep: racial inequities in health.
Authors: Williams DR
Source: J Health Soc Behav, 2012 Sep;53(3), p. 279-95.
PMID: 22940811
Related Citations

Back to top


Integrating multiple social statuses in health disparities research: the case of lung cancer.
Authors: Williams DR, Kontos EZ, Viswanath K, Haas JS, Lathan CS, MacConaill LE, Chen J, Ayanian JZ
Source: Health Serv Res, 2012 Jun;47(3 Pt 2), p. 1255-77.
EPub date: 2012 Mar 30.
PMID: 22568674
Related Citations

Back to top


Prostate cancer mortality and birth or adult residence in the southern United States.
Authors: Datta GD, Glymour MM, Kosheleva A, Chen JT
Source: Cancer Causes Control, 2012 Jul;23(7), p. 1039-46.
EPub date: 2012 May 1.
PMID: 22547136
Related Citations

Back to top


Elucidating the role of place in health care disparities: the example of racial/ethnic residential segregation.
Authors: White K, Haas JS, Williams DR
Source: Health Serv Res, 2012 Jun;47(3 Pt 2), p. 1278-99.
EPub date: 2012 Apr 19.
PMID: 22515933
Related Citations

Back to top


Research on discrimination and health: an exploratory study of unresolved conceptual and measurement issues.
Authors: Williams DR, John DA, Oyserman D, Sonnega J, Mohammed SA, Jackson JS
Source: Am J Public Health, 2012 May;102(5), p. 975-8.
EPub date: 2012 Mar 15.
PMID: 22420798
Related Citations

Back to top


Psychosocial stressors and cigarette smoking among African American adults in midlife.
Authors: Slopen N, Dutra LM, Williams DR, Mujahid MS, Lewis TT, Bennett GG, Ryff CD, Albert MA
Source: Nicotine Tob Res, 2012 Oct;14(10), p. 1161-9.
EPub date: 2012 Feb 24.
PMID: 22367977
Related Citations

Back to top