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Grant Details

Grant Number: 5R01CA140150-04 Interpret this number
Primary Investigator: Primack, Brian
Organization: University Of Pittsburgh At Pittsburgh
Project Title: Waterpipe Tobacco Smoking Among U.S. Adolescents and Young Adults
Fiscal Year: 2013
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Abstract

DESCRIPTION (provided by applicant): Tobacco smoking using a waterpipe (a.k.a., hookah) is an emerging trend and a threat to U.S. public health. Waterpipe tobacco smoke contains large amounts of toxicants (e.g., CO, tar, nicotine, and heavy metals) and has been associated with addiction and other adverse health consequences. Despite these facts, convenience sample studies demonstrate that 20-40 percent of U.S. University students report waterpipe tobacco smoking in the past year. Moreover, 30-50 percent of waterpipe tobacco smokers have never used cigarettes, suggesting that waterpipes deliver tobacco to millions of individuals who otherwise would have been naive to nicotine. Learning more about U.S. waterpipe users, mechanisms of waterpipe smoking uptake, and the trajectory and consequences of its use will be essential for developing targeted interventions to prevent waterpipe tobacco smoking from becoming a new strain in the U.S. tobacco epidemic. The American College Health Association's new National College Health Assessment (NCHA) surveys more than 90,000 individuals annually and will be the first large scale survey to include basic items that assess waterpipe tobacco smoking. This project leverages these data to help us determine the prevalence and correlates of waterpipe tobacco smoking among a large sample of U.S. university students (Specific Aim 1). Multivariable models will assess independent associations between waterpipe smoking outcomes and (1) respondent factors such as age, gender, race/ethnicity, socioeconomic status, and other substance use; and (2) environmental variables such as college/university setting, and geographic region. Next, we will use qualitative assessments to inform a theoretical framework describing the factors related to uptake of waterpipe tobacco smoking (Specific Aim 2). This component will involve (1) a national content analysis of waterpipe tobacco Web sites; (2) direct ethnographic observation of behavior in 8 different settings where waterpipe tobacco is smoked; and (3) 6 in- depth focus groups with waterpipe tobacco users stratified by age and gender. These analyses will inform our theoretical model describing the factors related to uptake of waterpipe tobacco smoking. Finally, we will conduct a nationally-representative, longitudinal study of 3700 individuals aged 15-30 investigating the trajectories and consequences of waterpipe tobacco smoking (Specific Aim 3). Data from this study will enable us (1) to test the conceptual model from Specific Aim 2; and (2) to determine longitudinal associations between waterpipe tobacco experimentation and subsequent tobacco use and intention outcomes. In sum, waterpipe tobacco smoking appears to be a growing public health threat, particularly among U.S. late adolescents and young adults. This timely and innovative project will combine analysis of an existing data set, intensive qualitative assessments, and an original longitudinal data collection to provide crucial information that will ultimately help develop interventions aimed at reducing the public health threat posed by waterpipe tobacco smoking. PUBLIC HEALTH RELEVANCE: Tobacco smoking using a waterpipe (a.k.a., hookah) is an emerging trend in the U.S. that poses a great threat to the public health. This project leverages the new inclusion of waterpipe smoking questions in a large national survey to determine how common waterpipe tobacco smoking is among college students nationwide. It will also feature an intensive qualitative component that will help us understand through on-site observations and focus groups why this behavior is increasing. Finally, it will include a nationally-representative, longitudinal data collection investigating the trajectories and consequences of waterpipe tobacco smoking.

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Publications

Associations of mental health problems with waterpipe tobacco and cigarette smoking among college students.
Authors: Primack BA, Land SR, Fan J, Kim KH, Rosen D
Source: Subst Use Misuse, 2013 Feb;48(3), p. 211-9.
EPub date: 2013 Jan 10.
PMID: 23302059
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150

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Associations between hookah tobacco smoking knowledge and hookah smoking behavior among US college students.
Authors: Nuzzo E, Shensa A, Kim KH, Fine MJ, Barnett TE, Cook R, Primack BA
Source: Health Educ Res, 2013 Feb;28(1), p. 92-100.
EPub date: 2012 Sep 17.
PMID: 22987864
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150

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Substance and hookah use and living arrangement among fraternity and sorority members at US colleges and universities.
Authors: Sidani JE, Shensa A, Primack BA
Source: J Community Health, 2013 Apr;38(2), p. 238-45.
PMID: 22903805
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Grant Numbers:
NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315 NCI NIH HHS - CA-140150
NCI NIH HHS - R01 CA140150

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US health policy related to hookah tobacco smoking.
Authors: Primack BA, Hopkins M, Hallett C, Carroll MV, Zeller M, Dachille K, Kim KH, Fine MJ, Donohue JM
Source: Am J Public Health, 2012 Sep;102(9), p. e47-51.
EPub date: 2012 Jul 24.
PMID: 22827447
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150

MeSH Terms:
United States Tobacco Smoke Pollution Demography
Smoking Cities Humans
Smoking Cessation Adult Health Policy

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ER vs. ED: a comparison of televised and real-life emergency medicine.
Authors: Primack BA, Roberts T, Fine MJ, Dillman Carpentier FR, Rice KR, Barnato AE
Source: J Emerg Med, 2012 Dec;43(6), p. 1160-6.
EPub date: 2012 Jul 4.
PMID: 22766407
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315

MeSH Terms:
United States Young Adult Humans
Aged Child Emergency Service, Hospital
Patients Child, Preschool Infant
Socioeconomic Factors Television Adult
Middle Aged Adolescent Female
Male

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Tobacco, marijuana, and alcohol use in university students: a cluster analysis.
Authors: Primack BA, Kim KH, Shensa A, Sidani JE, Barnett TE, Switzer GE
Source: J Am Coll Health, 2012;60(5), p. 374-86.
PMID: 22686360
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Grant Numbers:
NCATS NIH HHS - UL1 TR000005 NCRR NIH HHS - UL1 RR024153 NCI NIH HHS - K07 CA114315
NCI NIH HHS - K07-CA114315 NCI NIH HHS - CA-140150 NCI NIH HHS - R01 CA140150

MeSH Terms:
United States Young Adult Odds Ratio
Risk-Taking Humans Alcoholic Intoxication
Algorithms Students Alcohol Drinking
Multivariate Analysis Smoking Logistic Models
Substance-Related Disorders Cannabis Confidence Intervals
Universities Cluster Analysis Female
Male

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Waterpipe smoking among U.S. university students.
Authors: Primack BA, Shensa A, Kim KH, Carroll MV, Hoban MT, Leino EV, Eissenberg T, Dachille KH, Fine MJ
Source: Nicotine Tob Res, 2013 Jan;15(1), p. 29-35.
EPub date: 2012 May 28.
PMID: 22641433
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCI NIH HHS - R01-CA120142 NCI NIH HHS - R01 CA140150

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Role of video games in improving health-related outcomes: a systematic review.
Authors: Primack BA, Carroll MV, McNamara M, Klem ML, King B, Rich M, Chan CW, Nayak S
Source: Am J Prev Med, 2012 Jun;42(6), p. 630-8.
PMID: 22608382
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCRR NIH HHS - KL2 RR024154 NCRR NIH HHS - KL2 RR024154-02

MeSH Terms:
United States Young Adult Video Games
Self Care Humans Physical Therapy Modalities
Health Status Outcome and Process Assessment (Health Care) Aged
Child Aged, 80 and over Adult
Middle Aged Adolescent Female
Male

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Waterpipe tobacco and cigarette smoking among university students in Jordan.
Authors: Khabour OF, Alzoubi KH, Eissenberg T, Mehrotra P, Azab M, Carroll MV, Afifi RA, Primack BA
Source: Int J Tuberc Lung Dis, 2012 Jul;16(7), p. 986-92.
EPub date: 2012 Apr 16.
PMID: 22525279
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Grant Numbers:
NCI NIH HHS - R01-CA140150 FIC NIH HHS - R03-TW008371 NCI NIH HHS - K07 CA114315
NCI NIH HHS - R01-CA120142 NCI NIH HHS - R01 CA140150

MeSH Terms:
Young Adult Questionnaires Humans
Students Tobacco Products Smoking
Jordan Logistic Models Risk Factors
Adolescent Universities Female
Male Prevalence

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Association of established smoking among adolescents with timing of exposure to smoking depicted in movies.
Authors: Primack BA, Longacre MR, Beach ML, Adachi-Mejia AM, Titus LJ, Dalton MA
Source: J Natl Cancer Inst, 2012 Apr 4;104(7), p. 549-55.
EPub date: 2012 Mar 14.
PMID: 22423010
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Grant Numbers:
NCI NIH HHS - R01-CA077026 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCI NIH HHS - R01-CA108918 NCI NIH HHS - R01 CA077026 NCI NIH HHS - R01 CA140150
NCI NIH HHS - R01 CA108918

MeSH Terms:
Young Adult Age Factors Questionnaires
Adolescent Behavior Humans Child
Poisson Distribution Longitudinal Studies Vermont
Imitative Behavior Multivariate Analysis New Hampshire
Smoking Schools Motion Pictures as Topic
Follow-Up Studies Adolescent Time Factors
Female Male

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A comparison of cigarette- and hookah-related videos on YouTube.
Authors: Carroll MV, Shensa A, Primack BA
Source: Tob Control, 2012 Feb 23;null, p. null.
EPub date: 2012 Feb 23.
PMID: 22363069
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Grant Numbers:
NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150

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U.S. hookah tobacco smoking establishments advertised on the internet.
Authors: Primack BA, Rice KR, Shensa A, Carroll MV, DePenna EJ, Nakkash R, Barnett TE
Source: Am J Prev Med, 2012 Feb;42(2), p. 150-6.
PMID: 22261211
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCI NIH HHS - R01 CA140150

MeSH Terms:
United States Smoking Restaurants
Internet Advertising as Topic

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Motives for smoking in movies affect future smoking risk in middle school students: an experimental investigation.
Authors: Shadel WG, Martino SC, Setodji C, Haviland A, Primack BA, Scharf D
Source: Drug Alcohol Depend, 2012 Jun 1;123(1-3), p. 66-71.
EPub date: 2011 Nov 8.
PMID: 22074766
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Grant Numbers:
NIDA NIH HHS - R01DA022496 NIDA NIH HHS - R01 DA022496-01A2 NCI NIH HHS - K07 CA114315
NCI NIH HHS - R01 CA140150

MeSH Terms:
Age Factors Adolescent Behavior Motivation
Humans Child Attitude
Students Risk Smoking
Ethnic Groups Motion Pictures as Topic Adolescent
Female Male

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College students and use of K2: an emerging drug of abuse in young persons.
Authors: Hu X, Primack BA, Barnett TE, Cook RL
Source: Subst Abuse Treat Prev Policy, 2011 Jul 11;6, p. 16.
EPub date: 2011 Jul 11.
PMID: 21745369
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150

MeSH Terms:
Young Adult Age Factors Adolescent Behavior
Sex Characteristics Humans Students
Cannabinoids Street Drugs Substance-Related Disorders
Adolescent Universities Female
Male Prevalence

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Using ecological momentary assessment to determine media use by individuals with and without major depressive disorder.
Authors: Primack BA, Silk JS, DeLozier CR, Shadel WG, Dillman Carpentier FR, Dahl RE, Switzer GE
Source: Arch Pediatr Adolesc Med, 2011 Apr;165(4), p. 360-5.
PMID: 21464384
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Grant Numbers:
NCI NIH HHS - R01-CA140150 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NIMH NIH HHS - P01-MH41712 NCI NIH HHS - K07 CA114315-05

MeSH Terms:
Adolescent Behavior Child Behavior Humans
Child Depressive Disorder, Major Risk Factors
Cohort Studies Communications Media Health Surveys
Case-Control Studies Adolescent Female
Male

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Burnout among early career clinical investigators.
Authors: Primack BA, Dilmore TC, Switzer GE, Bryce CL, Seltzer DL, Li J, Landsittel DP, Kapoor WN, Rubio DM
Source: Clin Transl Sci, 2010 Aug;3(4), p. 186-8.
PMID: 20718821
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Grant Numbers:
NCI NIH HHS - K07 CA114315-04S1 NCI NIH HHS - R01-CA140150 NCRR NIH HHS - UL1 RR024153
NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315 NCRR NIH HHS - K12 RR023267-03
NCI NIH HHS - K07 CA114315-04

MeSH Terms:
Questionnaires Humans African Americans
Burnout, Professional Faculty, Medical Medical Staff
Cross-Sectional Studies Indians, North American Minority Groups
Hispanic Americans Biomedical Research European Continental Ancestry Group
Adult Asian Americans Career Mobility
Male Female Prevalence

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Smoking motives in movies are important for understanding adolescent smoking: a preliminary investigation.
Authors: Shadel WG, Martino SC, Haviland A, Setodji C, Primack BA
Source: Nicotine Tob Res, 2010 Aug;12(8), p. 850-4.
EPub date: 2010 Jun 24.
PMID: 20576800
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Grant Numbers:
NCI NIH HHS - K07 CA114315-04S1 NCI NIH HHS - R01 CA140150-02 NCI NIH HHS - K07 CA114315
NCI NIH HHS - K07 CA114315-04 NIDA NIH HHS - R01 DA022496

MeSH Terms:
Smoking Adolescent Behavior Humans
Motion Pictures as Topic Child Adolescent
Male Female

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Water pipe tobacco smoking among university students in Jordan.
Authors: Azab M, Khabour OF, Alkaraki AK, Eissenberg T, Alzoubi KH, Primack BA
Source: Nicotine Tob Res, 2010 Jun;12(6), p. 606-12.
EPub date: 2010 Apr 23.
PMID: 20418383
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Grant Numbers:
NCI NIH HHS - K07 CA114315-04S1 NIDA NIH HHS - R01-DA024876 NCI NIH HHS - R01 CA140150-03
FIC NIH HHS - R03-TW008371 NCI NIH HHS - R01 CA140150-02 NCI NIH HHS - K07 CA114315
NCI NIH HHS - K07-CA114315 NCI NIH HHS - K07 CA114315-04 NCI NIH HHS - R01-CA120142
NCI NIH HHS - R01 CA140150

MeSH Terms:
Young Adult Smoking Jordan
Humans Adult Universities
Students Male Female

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Waterpipe and cigarette smoking among college athletes in the United States.
Authors: Primack BA, Fertman CI, Rice KR, Adachi-Mejia AM, Fine MJ
Source: J Adolesc Health, 2010 Jan;46(1), p. 45-51.
EPub date: 2009 Jul 8.
PMID: 20123257
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Grant Numbers:
NCI NIH HHS - K07 CA114315-04S1 NCI NIH HHS - R01 CA140150-01A1 NCI NIH HHS - R01 CA140150-03
NCI NIH HHS - R01 CA140150-02 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCI NIH HHS - K07 CA114315-04 NCI NIH HHS - K07 CA114315-03 NCI NIH HHS - R01 CA140150

MeSH Terms:
United States Young Adult Odds Ratio
Humans Sports Students
Multivariate Analysis Smoking Data Collection
Adolescent Universities Female
Male

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Water-pipe tobacco smoking among middle and high school students in Arizona.
Authors: Primack BA, Walsh M, Bryce C, Eissenberg T
Source: Pediatrics, 2009 Feb;123(2), p. e282-8.
PMID: 19171581
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Grant Numbers:
NIDA NIH HHS - R01-DA024876 NCI NIH HHS - R01 CA140150-01A1 NCI NIH HHS - R01 CA140150-03
NCI NIH HHS - R01-CA103827 NCI NIH HHS - K07 CA114315 NCI NIH HHS - K07-CA114315
NCI NIH HHS - R01-CA120142 NCI NIH HHS - K07 CA114315-03 NCI NIH HHS - R01 CA140150

MeSH Terms:
Smoking Humans Arizona
Adolescent Water Male
Female Prevalence

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Prevalence of and associations with waterpipe tobacco smoking among U.S. university students.
Authors: Primack BA, Sidani J, Agarwal AA, Shadel WG, Donny EC, Eissenberg TE
Source: Ann Behav Med, 2008 Aug;36(1), p. 81-6.
EPub date: 2008 Aug 22.
PMID: 18719977
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Grant Numbers:
NCI NIH HHS - R01-CA103827 FIC NIH HHS - R01-TW005962 NCI NIH HHS - K07 CA114315
NIDA NIH HHS - R01-DA11082 NCI NIH HHS - K07-CA114315 NCI NIH HHS - K07 CA114315-02
NCI NIH HHS - R01 CA140150

MeSH Terms:
Young Adult Regression Analysis Reference Values
Tobacco Use Disorder Humans Models, Statistical
Students Water Cross-Sectional Studies
Smoking Social Perception Filtration
Tobacco Health Knowledge, Attitudes, Practice Universities
Administration, Inhalation Female Male

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An old custom, a new threat to tobacco control.
Authors: Primack BA, Aronson JD, Agarwal AA
Source: Am J Public Health, 2006 Aug;96(8), p. 1339.
EPub date: 2006 Jun 29.
PMID: 16809578
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Grant Numbers:
NCI NIH HHS - K07 CA114315 NCI NIH HHS - R01 CA140150 NCI NIH HHS - K07 CA114315-01A1

MeSH Terms:
Flavoring Agents Smoking Restaurants
Humans Marketing Tobacco Industry
Adolescent

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