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Grant Details

Grant Number: 5U01CA159533-03 Interpret this number
Primary Investigator: Zhu, Shu-Hong
Organization: University Of California San Diego
Project Title: Using Nrt and Quitline Services to Help Hospitalized Smokers Stay Quit
Fiscal Year: 2012
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Abstract

When smokers are hospitalized they quit smoking, either voluntarily or involuntarily. Most of them, however, go back to smoking soon after discharge. Research has shown that extended follow-up counseling post-discharge can help prevent relapse. However, it is difficult for hospitals to conduct extended follow up for patients after discharge. The proposed study aims to establish a practical model in which hospitals will work with a state quitline in the following manner: Hospital staff will conduct bedside counseling and then refer patients to the quitline. Quitline counselors will proactively call patients post-discharge and provide counseling up to 2 months. With the proposed project we intend to establish a practical model that lends itself to broader dissemination, while testing the effectiveness ofthe interventions with the rigor of a randomized design. We plan to demonstrate in a randomized trial the effects of two interventions, dispensing nicotine patches at discharge and providing proactive telephone counseling soon after discharge, on the long term quit rates of hospitalized smokers in a 2 x 2 factorial design. All eligible patients receive brief counseling from hospital staff. This is usual care. Study participants are randomly assigned into one ofthe four conditions: usual care, nicotine patch post discharge, telephone counseling post discharge, or both patch and counseling post discharge. It is hypothesized that the patch and counseling each has an independent effect and their combined effect is greater than that for either single intervention. We also intend to compare the cost-effectiveness ofthe interventions: patch alone, counseling alone, and combined interventions, against the usual care condition. Further, the proposed study will allow us to examine if a patient's medical diagnosis is a moderating factor for intervention effects such that patients with certain diagnoses benefit more from the interventions than patients with other diagnoses. RELEVANCE (See instructions): , . - ,, ...,,. The hospital-quitline partnership model proposed to be tested in the study can help increase the number of hospitalized smokers to quit during their stay and remain quit post-discharge.

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Publications

Health and economic effects from linking bedside and outpatient tobacco cessation services for hospitalized smokers in two large hospitals: study protocol for a randomized controlled trial.
Authors: Fellows JL, Mularski R, Waiwaiole L, Funkhouser K, Mitchell J, Arnold K, Luke S
Source: Trials, 2012 Aug 1;13, p. 129.
EPub date: 2012 Aug 1.
PMID: 22853325
Related Citations

Grant Numbers:
NHLBI NIH HHS - HL105231 NHLBI NIH HHS - 1U01HL1053231 NHLBI NIH HHS - HL105232
NHLBI NIH HHS - HL105233 NHLBI NIH HHS - HL105218 NIDA NIH HHS - DA031515
NHLBI NIH HHS - HL105229 NCI NIH HHS - CA159533

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Nicotine patches and quitline counseling to help hospitalized smokers stay quit: study protocol for a randomized controlled trial.
Authors: Cummins S, Zhu SH, Gamst A, Kirby C, Brandstein K, Klonoff-Cohen H, Chaplin E, Morris T, Seymann G, Lee J
Source: Trials, 2012 Aug 1;13, p. 128.
EPub date: 2012 Aug 1.
PMID: 22853197
Related Citations

Grant Numbers:
NHLBI NIH HHS - HL105231 NHLBI NIH HHS - HL105232 NHLBI NIH HHS - HL105233
NHLBI NIH HHS - HL105218 NIDA NIH HHS - DA031515 NHLBI NIH HHS - HL105229
NCI NIH HHS - CA159533

MeSH Terms:
Administration, Cutaneous Telephone Humans
Nicotinic Agonists Hotlines Counseling
Research Design Recurrence Aftercare
California Drug Costs Smoking
Nicotine Cost-Benefit Analysis Smoking Cessation
Treatment Outcome Tobacco Use Cessation Products Hospital Costs
Inpatients Patient Discharge Time Factors
Transdermal Patch

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Web-based smoking cessation intervention that transitions from inpatient to outpatient: study protocol for a randomized controlled trial.
Authors: Harrington KF, McDougal JA, Pisu M, Zhang B, Sadasivam RS, Houston TK, Bailey WC, CHART Collaborative Group
Source: Trials, 2012 Aug 1;13, p. 123.
EPub date: 2012 Aug 1.
PMID: 22852802
Related Citations

Grant Numbers:
NIDA NIH HHS - R01DA017971 NHLBI NIH HHS - HL105231 NHLBI NIH HHS - HL105232
NCI NIH HHS - R01CA129091 NHLBI NIH HHS - HL105233 NHLBI NIH HHS - HL105218
NIDA NIH HHS - DA031515 NHLBI NIH HHS - HL105229 NCI NIH HHS - CA159533
NCATS NIH HHS - UL1 TR000161 NIDA NIH HHS - 1U01DA031515

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Overview of the Consortium of Hospitals Advancing Research on Tobacco (CHART).
Authors: Riley WT, Stevens VJ, Zhu SH, Morgan G, Grossman D
Source: Trials, 2012 Aug 1;13, p. 122.
EPub date: 2012 Aug 1.
PMID: 22852768
Related Citations

Grant Numbers:
NHLBI NIH HHS - U01HL52333 NCI NIH HHS - U01CA159533 NHLBI NIH HHS - U01HL105229
NHLBI NIH HHS - RC1HL099668 NHLBI NIH HHS - U01HL105218 NIDA NIH HHS - U01DA031515
NHLBI NIH HHS - U01HL105232 NHLBI NIH HHS - U01HL105231

MeSH Terms:
United States Cooperative Behavior Humans
Interdisciplinary Communication Organizational Objectives Recurrence
Smoking Hospitalization Biomedical Research
Smoking Cessation National Institute on Drug Abuse (U.S.) Treatment Outcome
Patient Discharge Hospitals National Heart, Lung, and Blood Institute (U.S.)
Research Support as Topic

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