|Grant Number:||5R01CA151251-03 Interpret this number|
|Primary Investigator:||Bricker, Jonathan|
|Organization:||Fred Hutchinson Cancer Research Center|
|Project Title:||Acceptance & Commitment Therapy for Smoking Cessation|
DESCRIPTION (provided by applicant): While effective smoking cessation treatments exist, there is significant room for improvement. Even with the current standard counseling plus pharmacotherapy, an average of 81 percent to 86 percent of smokers will relapse to smoking. Little attention has been placed on testing new behavioral cessation treatments aimed at increasing quit rates. To address this critical need, the current study will test the effectiveness of a newly emerging counseling approach called Acceptance & Commitment Therapy (ACT). To date, three trials of ACT for smoking cessation have been conducted. Overall, these three trials have been promising with the ACT intervention groups obtaining about 30 percent to 35 percent quit rates at 12 months post intervention-about double the 14 percent to 19 percent quit rates at 12 months post intervention for CBT plus NRT. The results of each trial suggest that ACT is a promising counseling approach for smoking cessation. However, only one study compared ACT with standard cognitive behavioral counseling (CBT) and all three studies had major methodological limitations which make it difficult to draw definitive conclusions about ACT's effectiveness for smoking cessation. Accordingly, a well-powered randomized trial comparing ACT with CBT for smoking cessation is now needed. In addition to providing important information about the comparative effectiveness of these treatment approaches, such a trial would allow for testing of the underlying processes through which ACT is hypothesized to exert its impact. The overall aim of this 5-year project is to capitalize on the strong theoretical and promising empirical evidence for ACT as an intervention for smoking cessation by comparing the effectiveness of group-delivered ACT against standard CBT counseling when both are offered with nicotine replacement therapy (NRT) and delivered within a real world health care setting. The specific aims of this research are to: (1) Determine the effectiveness of ACT as a group-delivered smoking cessation intervention plus NRT patch as compared to standard care group-delivered CBT counseling plus NRT patch; (2) Determine if the effectiveness of ACT is, as hypothesized, mediated by two key theory-based factors: (a) acceptance of internal cues to smoke (sensations, emotions, and thoughts) and (b) commitment to quitting smoking despite internal cues to smoke. The secondary aim will be to explore the role of quit attempts, alcohol use, gender, and recent depressive and anxiety symptoms as moderators of the ACT intervention effect. The proposed intervention is highly innovative and addresses an important research need - evaluating novel forms of counseling to enhance smoking cessation outcomes. If effective, the proposed intervention stands to make a significant impact and the ACT protocol could be disseminated in other clinical settings around the U.S. PUBLIC HEALTH RELEVANCE: This application responds to the great U.S. public health need to help adults quit smoking. This 5-year project will determine (1) the effect of ACT for smoking cessation compared with the current standard CBT, (2) the extent to which ACT for smoking cessation is mediated by changes intermediate theory-based process of smoking cessation. If effective, the proposed intervention stands to make a significant impact and the ACT protocol could be disseminated in other clinical settings around the U.S.
Climbing above the forest and the trees: three future directions in addiction treatment research.
Authors: Bricker JB
Source: Addiction, 2015 Mar;110(3), p. 414-5.
Web-based acceptance and commitment therapy smoking cessation treatment for smokers with depressive symptoms.
Authors: Jones HA, Heffner JL, Mercer L, Wyszynski CM, Vilardaga R, Bricker JB
Source: J Dual Diagn, 2015;11(1), p. 56-62.
Feature-level analysis of a novel smartphone application for smoking cessation.
Authors: Heffner JL, Vilardaga R, Mercer LD, Kientz JA, Bricker JB
Source: Am J Drug Alcohol Abuse, 2015 Jan;41(1), p. 68-73.
EPub date: 2014 Nov 14.
Randomized, controlled pilot trial of a smartphone app for smoking cessation using acceptance and commitment therapy.
Authors: Bricker JB, Mull KE, Kientz JA, Vilardaga R, Mercer LD, Akioka KJ, Heffner JL
Source: Drug Alcohol Depend, 2014 Oct 1;143, p. 87-94.
EPub date: 2014 Jul 17.
Randomized trial of telephone-delivered acceptance and commitment therapy versus cognitive behavioral therapy for smoking cessation: a pilot study.
Authors: Bricker JB, Bush T, Zbikowski SM, Mercer LD, Heffner JL
Source: Nicotine Tob Res, 2014 Nov;16(11), p. 1446-54.
EPub date: 2014 Jun 16.
Can Acceptance & Commitment Therapy be delivered with fidelity as a brief telephone-intervention?
Authors: Schimmel-Bristow A, Bricker JB, Comstock B
Source: Addict Behav, 2012 Apr;37(4), p. 517-20.
EPub date: 2011 Nov 17.
Comparison of motivational interviewing with acceptance and commitment therapy: a conceptual and clinical review.
Authors: Bricker J, Tollison S
Source: Behav Cogn Psychother, 2011 Oct;39(5), p. 541-59.
EPub date: 2011 Feb 22.