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Grant Details

Grant Number: 3R01CA125224-03S1 Interpret this number
Primary Investigator: Connolly, Gregory
Organization: Harvard University (Sch Of Public Hlth)
Project Title: Subjective and Behavioral Responses to Prep Design and Marketing
Fiscal Year: 2010
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Abstract

DESCRIPTION (provided by applicant): Tobacco manufacturers have recently introduced what the Institute of Medicine describes as potential reduced (tobacco) exposure products (PREPs), including modified cigarettes, novel nicotine delivery devices and oral snuff. These products are promoted with implied and explicit claims of reduced health risk, made without independent scientific validation. Manufacturers have also altered the design of PREPS, potentially in order to enhance consumer acceptability, contribute to dependence, and alter consumer perceptions of PREP "safety." Despite the lack of research to support PREP health claims, PREPs ultimately may achieve market success through manipulation of product design and marketing to enhance consumer appeal and dependence. PREPs could increase youth initiation or experimentation with tobacco, deter quitting, and help to maintain use among current smokers, thus increasing tobacco-related cancer and other health risk. An effective understanding of the influence of PREP design and marketing on consumer response is urgently required to complement existing research on tobacco harm reduction, and provide an effective public health response to the introduction of new tobacco products. The objectives of this project are to examine the inter-relationships between PREP design and marketing and their effects on consumer response and acceptance, in order to evaluate the potential commercial impact of new and future PREPs. Specifically, the project aims include: 1) identifying and evaluating design characteristics unique to PREPs; 2) evaluating the interaction between messaging and product design; and 3) assessing the influence of product design on smoking behavior and exposure. Multiple dimensions of PREP design and marketing will be investigated, with particular focus on behavioral and sensory response to PREPs as compared with conventional cigarettes. The objectives of this project are to examine the inter-relationships between PREP design and marketing and their effects on consumer response and acceptance, in order to evaluate the potential commercial impact of new and future PREPs. Multiple dimensions of PREP design and marketing will be investigated, with particular focus on behavioral and sensory response to PREPs as compared with conventional cigarettes.

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Publications

Gender and racial differences in smoking of long/ultra-long and king size cigarettes among U.S. adult smokers, NHANES 1999-2012.
Authors: Agaku IT, Vardavas CI, Ayo-Yusuf OA, Alpert HR, Connolly GN
Source: Drug Alcohol Depend, 2014 Mar 1;136, p. 28-35.
EPub date: 2013 Dec 24.
PMID: 24417962
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Predictors and patterns of cigarette and smokeless tobacco use among adolescents in 32 countries, 2007-2011.
Authors: Agaku IT, Ayo-Yusuf OA, Vardavas CI, Connolly G
Source: J Adolesc Health, 2014 Jan;54(1), p. 47-53.
EPub date: 2013 Sep 20.
PMID: 24060573
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Cigarette rod length and its impact on serum cotinine and urinary total NNAL levels, NHANES 2007-2010.
Authors: Agaku IT, Vardavas CI, Connolly GN
Source: Nicotine Tob Res, 2014 Jan;16(1), p. 100-7.
EPub date: 2013 Sep 21.
PMID: 24057994
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Proposed cutoff for identifying adult smokeless tobacco users with urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanonol: an aggregated analysis of NHANES 2007-2010 data.
Authors: Agaku IT, Vardavas CI, Connolly G
Source: Nicotine Tob Res, 2013 Nov;15(11), p. 1956-61.
EPub date: 2013 Aug 16.
PMID: 23956252
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Use of conventional and novel smokeless tobacco products among US adolescents.
Authors: Agaku IT, Ayo-Yusuf OA, Vardavas CI, Alpert HR, Connolly GN
Source: Pediatrics, 2013 Sep;132(3), p. e578-86.
EPub date: 2013 Aug 5.
PMID: 23918889
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Has the tobacco industry evaded the FDA's ban on 'Light' cigarette descriptors?
Authors: Connolly GN, Alpert HR
Source: Tob Control, 2014 Mar;23(2), p. 140-5.
EPub date: 2013 Mar 13.
PMID: 23485704
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Public attitudes regarding banning of cigarettes and regulation of nicotine.
Authors: Connolly GN, Behm I, Healton CG, Alpert HR
Source: Am J Public Health, 2012 Apr;102(4), p. e1-2.
EPub date: 2012 Feb 16.
PMID: 22397353
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Role of cigarette sensory cues in modifying puffing topography.
Authors: Rees VW, Kreslake JM, Wayne GF, O'Connor RJ, Cummings KM, Connolly GN
Source: Drug Alcohol Depend, 2012 Jul 1;124(1-2), p. 1-10.
EPub date: 2012 Feb 25.
PMID: 22365895
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R. J. Reynolds goes international with new dissolvable tobacco products.
Authors: Seidenberg AB, Rees VW, Connolly GN
Source: Tob Control, 2012 May;21(3), p. 368-9.
EPub date: 2011 Oct 7.
PMID: 21984408
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Influence of measurement setting and home smoking policy on smoking topography.
Authors: June KM, Norton KJ, Rees VW, O'Connor RJ
Source: Addict Behav, 2012 Jan;37(1), p. 42-6.
EPub date: 2011 Aug 2.
PMID: 21862228
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Electronic cigarettes: a new 'tobacco' industry?
Authors: Noel JK, Rees VW, Connolly GN
Source: Tob Control, 2011 Jan;20(1), p. 81.
EPub date: 2010 Oct 7.
PMID: 20930060
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Swedish Match marketing on YouTube.
Authors: Seidenberg AB, Rees VW, Connolly GN
Source: Tob Control, 2010 Dec;19(6), p. 512-3.
EPub date: 2010 Oct 7.
PMID: 20930059
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Applying toxicological risk assessment principles to constituents of smokeless tobacco products: implications for product regulation.
Authors: Ayo-Yusuf OA, Connolly GN
Source: Tob Control, 2011 Jan;20(1), p. 53-7.
EPub date: 2010 Oct 5.
PMID: 20924040
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Assessing consumer responses to potential reduced-exposure tobacco products: a review of tobacco industry and independent research methods.
Authors: Rees VW, Kreslake JM, Cummings KM, O'Connor RJ, Hatsukami DK, Parascandola M, Shields PG, Connolly GN
Source: Cancer Epidemiol Biomarkers Prev, 2009 Dec;18(12), p. 3225-40.
PMID: 19959675
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