National Cancer Institute
Cancer Control & Population Sciences Home - NCI's Bridge to Public Health Research, Practice and Policy

Grant Details

Grant Number: 5R01CA113932-05 Interpret this number
Primary Investigator: Dignan, Mark
Organization: University Of Kentucky
Project Title: Structure M.tuberculosis Adenosine Kinase Design Antimicrobial Nucleoside Analogs
Fiscal Year: 2009
Back to top


Abstract

DESCRIPTION (provided by applicant): The University of Kentucky's Cancer Control Program, Department of Behavioral Science , Kentucky Cancer Program, and community partners are proposing a five-year, community-based, participatory project to increase colorectal cancer screening in rural Appalachian Kentucky (51 counties in eastern Kentucky). Compared with the rest of the U.S., Appalachian Kentucky is medically underserved, economically distressed, and disproportionately burdened with different types of cancer. Data from the Behavioral Risk Factor Surveillance System indicates that approximately 36% of respondents in Appalachian Kentucky reported screening for colorectal cancer (FOBT or flexible sigmoidoscopy or colonoscopy) in accordance with guidelines of the US Preventive Services Task Force compared to 43.5% in Kentucky and 53% nationwide. Specific aims of this project are to: 1) Build on a foundation of community partnerships in Appalachian Kentucky and develop a network of community partners capable of fostering colorectal cancer screening; 2) Use results from a pilot project and, in collaboration with community partners, pretest an intervention to increase screening for colorectal cancer in rural Appalachian Kentucky; 3) Recruit primary health care providers for the project, conduct a baseline assessment and implement an intervention to increase colorectal cancer screening in primary care practices; and, 4) Evaluate the effectiveness of the intervention in increasing colorectal cancer using a randomized design involving primary care practices assigned to intervention or control based on a readiness to change score and conduct qualitative key informant interviews and process evaluations. Methods for achieving these aims are described in detail in Section D (Research Design and Methods) and include conducting focus groups, recruiting 64 primary care practices (32 control, 32 intervention), delivering an educational intervention consisting of 4 modules, collecting colorectal cancer screening data from 60 medical records/intervention practice, and assessing the impact of the intervention.

Back to top


Publications

How do rural health care providers and patients view barriers to colorectal cancer screening? Insights from appalachian kentucky.
Authors: Hatcher J, Dignan MB, Schoenberg N
Source: Nurs Clin North Am, 2011 Jun;46(2), p. 181-92, vi.
PMID: 21501729
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA113932-01 NCI NIH HHS - CA 11932

MeSH Terms:
Attitude of Health Personnel Rural Population Attitude to Health
Diagnostic Tests, Routine Humans Rural Health Services
Aged Communication Barriers Health Services Accessibility
Focus Groups Mass Screening Health Care Surveys
Patient Acceptance of Health Care Risk Management Kentucky
Middle Aged Appalachian Region Anecdotes as Topic
Male Colorectal Neoplasms Female

Back to top


Human papillomavirus (HPV) vaccine availability, recommendations, cost, and policies among health departments in seven Appalachian states.
Authors: Katz ML, Reiter PL, Kluhsman BC, Kennedy S, Dwyer S, Schoenberg N, Johnson A, Ely G, Roberto KA, Lengerich EJ, Brown P, Paskett ED, Dignan M
Source: Vaccine, 2009 May 21;27(24), p. 3195-200.
EPub date: 2009 Apr 7.
PMID: 19446191
Related Citations

Grant Numbers:
NCI NIH HHS - CA113932 NCI NIH HHS - CA107079 NCI NIH HHS - U01 CA114622-04
NCI NIH HHS - K07 CA107079-04 NCRR NIH HHS - UL1 RR025755 NCI NIH HHS - P30 CA016058-34
NCI NIH HHS - P30CA016058

MeSH Terms:
Humans Papillomavirus Vaccines Health Policy
Appalachian Region Immunization Female

Back to top




Last Updated: August 24, 2012
NIH - Turning Discovery Into Health
National Cancer InstituteU.S. National Institutes of HealthNational Cancer Institute