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Grant Details

Grant Number: 5R01CA097263-05 Interpret this number
Primary Investigator: Vernon, Sally
Organization: University Of Texas Hlth Sci Ctr Houston
Project Title: Tailored Interactive Intervention to Increase Crc Screen
Fiscal Year: 2006
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Abstract

DESCRIPTION (provided by applicant): Colorectal cancer (CRC) is the 2nd leading cause of cancer deaths in the U.S. and CRC risk increases with age. Most organizations suggest that, for those at average risk screening should be initiated at age 50. Colorectal cancer screening (CRCS) is cost-effective and offers the possibility of early detection as well as prevention. However, the use of every CRCS test is low and has not increased substantially in recent years. Clearly, interventions to increase screening are needed. The primary goal of this 5-year research project is to conduct a prospective randomized trial of a tailored interactive computer-based intervention to increase patient completion of CRCS among patients aged 50-64 years in a multi-specialty primary care practice in Houston, TX. A stratified random sample based on sex and prior screening history will be recruited. The primary outcome will be completion of any CRCS test (following ACS guidelines) within 6 months of the intervention. Secondary goals are to increase understanding of factors that predict completion of CRCS and to assess the cost-effectiveness of the intervention. The transtheoretical (stages of change) model will be used to guide intervention development. To implement our specific aims we will use Intervention Mapping, a framework for systematic health promotion program planning that incorporates theory and empiric evidence to identify determinants of a behavior, develop intervention objectives, and select methods and strategies for an intervention. The intervention will be delivered immediately prior to a patient's clinic visit via a personal computer installed in the clinic's Patient Education Center. It will be an interactive audiovisual program tailored to a participant's status on a series of variables including readiness to engage in CRCS. The interactive program will generate a checklist of questions and concerns identified by the patient that can be used to initiate a discussion about CRCS with the physician. Two comparison groups will be included: a no-contact control group and a control group who receive generic printed CRCS educational materials immediately prior to their clinic visit. All three groups will involve the provision of a physician reminder placed in the medical chart prior to the clinic visit. Telephone follow-up and medical record review will be conducted 6 months after delivery of the intervention to ascertain completion of CRCS.

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Publications

Acceptability of narratives to promote colorectal cancer screening in an online community.
Authors: Hwang KO, Trickey AW, Graham AL, Thomas EJ, Street RL Jr, Kraschnewski JL, Vernon SW
Source: Prev Med, 2012 Jun;54(6), p. 405-7.
EPub date: 2012 Mar 31.
PMID: 22498021
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Grant Numbers:
NCRR NIH HHS - UL1 RR024148 NCI NIH HHS - R01 CA97263 NCRR NIH HHS - 5KL2RR024149-05
NCRR NIH HHS - KL2 RR024149 NCRR NIH HHS - KL2 RR024149-05

MeSH Terms:
Obesity Attitude to Health Humans
Information Dissemination Aged Texas
Overweight Employment Health Promotion
Life Style Patient Acceptance of Health Care Logistic Models
European Continental Ancestry Group Adult Early Detection of Cancer
Middle Aged Anecdotes as Topic African Continental Ancestry Group
Male Internet Colorectal Neoplasms
Female

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A randomized controlled trial of a tailored interactive computer-delivered intervention to promote colorectal cancer screening: sometimes more is just the same.
Authors: Vernon SW, Bartholomew LK, McQueen A, Bettencourt JL, Greisinger A, Coan SP, Lairson D, Chan W, Hawley ST, Myers RE
Source: Ann Behav Med, 2011 Jun;41(3), p. 284-99.
PMID: 21271365
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA097263-01 NCI NIH HHS - R01 NCI RO1 CA97263

MeSH Terms:
Humans Outcome and Process Assessment (Health Care) Aged
Health Promotion Computer-Assisted Instruction Patient Acceptance of Health Care
Health Surveys Early Detection of Cancer Health Behavior
Middle Aged Colorectal Neoplasms Female
Internet Male Consumer Health Information

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Association of area socioeconomic status and breast, cervical, and colorectal cancer screening: a systematic review.
Authors: Pruitt SL, Shim MJ, Mullen PD, Vernon SW, Amick BC 3rd
Source: Cancer Epidemiol Biomarkers Prev, 2009 Oct;18(10), p. 2579-99.
PMID: 19815634
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Grant Numbers:
NCI NIH HHS - R01 CA112223 NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA112223-03
NCI NIH HHS - 2 R25 CA 57712 NCI NIH HHS - R25 CA057712-16 NCI NIH HHS - R01 CA097263-05

MeSH Terms:
Uterine Cervical Neoplasms Social Class Humans
Early Detection of Cancer Breast Neoplasms Male
Female Colorectal Neoplasms

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Implementing an intervention to promote colon cancer screening through e-mail over the Internet: lessons learned from a pilot study.
Authors: Chan EC, Vernon SW
Source: Med Care, 2008 Sep;46(9 Suppl 1), p. S117-22.
PMID: 18725823
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Grant Numbers:
NCI NIH HHS - R21 CA89475 NCI NIH HHS - R01 CA112223 NCI NIH HHS - R01 CA97263
NCI NIH HHS - 5R21CA89475 AHRQ HHS - 1 K02 HS11421-01

MeSH Terms:
United States Diagnostic Tests, Routine Humans
Aged Primary Health Care Pilot Projects
Health Promotion Patient Education as Topic Electronic Mail
Patient Acceptance of Health Care Health Knowledge, Attitudes, Practice Middle Aged
Physician's Practice Patterns Physician-Patient Relations Colorectal Neoplasms
Female Male

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Validation of a questionnaire to assess self-reported colorectal cancer screening status using face-to-face administration.
Authors: Fisher DA, Voils CI, Coffman CJ, Grubber JM, Dudley TK, Vernon SW, Bond JH, Provenzale D
Source: Dig Dis Sci, 2009 Jun;54(6), p. 1297-306.
EPub date: 2008 Aug 23.
PMID: 18726152
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA97263 NCI NIH HHS - R21 CA102379-01A1 NCI NIH HHS - R21 CA102379
NIDDK NIH HHS - K24 DK002926 NCI NIH HHS - R01 CA76330 NCI NIH HHS - R21 CA102379-02

MeSH Terms:
Mass Screening Questionnaires Reproducibility of Results
Humans Health Behavior Aged
Middle Aged Male Female
Colorectal Neoplasms

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Translational research and good behavior.
Authors: Hiatt RA, Miller SM, Vernon SW
Source: Cancer Epidemiol Biomarkers Prev, 2007 Nov;16(11), p. 2184-5.
PMID: 18006904
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Grant Numbers:
NCI NIH HHS - 2P01 CA057586-09A2 NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA104979
NCI NIH HHS - P30 CA06927

MeSH Terms:
Neoplasms Behavior Biomedical Research
Humans Social Sciences Behavioral Research

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Racial disparities and socioeconomic status in association with survival in a large population-based cohort of elderly patients with colon cancer.
Authors: Du XL, Fang S, Vernon SW, El-Serag H, Shih YT, Davila J, Rasmus ML
Source: Cancer, 2007 Aug 1;110(3), p. 660-9.
PMID: 17582625
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Grant Numbers:
NCI NIH HHS - R01-CA97263

MeSH Terms:
United States Educational Status Neoplasm Staging
Humans SEER Program Aged
Socioeconomic Factors Survival Rate Aged, 80 and over
Ethnic Groups Social Class Risk Factors
Cohort Studies Treatment Outcome Colonic Neoplasms
Male

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Which women aren't getting mammograms and why? (United States).
Authors: Meissner HI, Breen N, Taubman ML, Vernon SW, Graubard BI
Source: Cancer Causes Control, 2007 Feb;18(1), p. 61-70.
PMID: 17186422
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA76330

MeSH Terms:
United States Mammography Questionnaires
Humans Breast Neoplasms Demography
Socioeconomic Factors Mass Screening Health Care Surveys
Patient Acceptance of Health Care Adult Middle Aged
Physician-Patient Relations Female

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Correlates of repeat and recent mammography for women ages 45 to 75 in the 2002 to 2003 Health Information National Trends Survey (HINTS 2003).
Authors: Rakowski W, Meissner H, Vernon SW, Breen N, Rimer B, Clark MA
Source: Cancer Epidemiol Biomarkers Prev, 2006 Nov;15(11), p. 2093-101.
PMID: 17119033
Related Citations

Grant Numbers:
NCI NIH HHS - K05-CA90485 NCI NIH HHS - R01-CA76330 NCI NIH HHS - R01-CA97263
NCI NIH HHS - R01-CA105486 NCI NIH HHS - K07-CA87070

MeSH Terms:
United States Odds Ratio Mammography
Reproducibility of Results Humans Aged
Breast Neoplasms Multivariate Analysis Mass Screening
Social Class Logistic Models Health Surveys
Middle Aged Female Prevalence

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Barriers to colorectal cancer screening: a comparison of reports from primary care physicians and average-risk adults.
Authors: Klabunde CN, Vernon SW, Nadel MR, Breen N, Seeff LC, Brown ML
Source: Med Care, 2005 Sep;43(9), p. 939-44.
PMID: 16116360
Related Citations

Grant Numbers:
NCI NIH HHS - R21 CA89475 NCI NIH HHS - R01 CA97263 NCI NIH HHS - R01 CA76330

MeSH Terms:
United States Diagnostic Tests, Routine Humans
Retrospective Studies Referral and Consultation Aged
Primary Health Care Communication Barriers Health Education
Mass Screening Health Care Surveys Aged, 80 and over
Logistic Models Middle Aged Physician's Practice Patterns
Colorectal Neoplasms Female Male

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Prevalence of colorectal cancer screening in a large medical organization.
Authors: Hawley ST, Vernon SW, Levin B, Vallejo B
Source: Cancer Epidemiol Biomarkers Prev, 2004 Feb;13(2), p. 314-9.
PMID: 14973108
Related Citations

Grant Numbers:
NCI NIH HHS - R01 CA97263 AHRQ HHS - K02 HS00007-03

MeSH Terms:
Age Factors Occult Blood Sex Factors
Humans Retrospective Studies Aged
Primary Health Care Sigmoidoscopy Mass Screening
Colonoscopy Aged, 80 and over Patient Compliance
Middle Aged Colorectal Neoplasms Female
Male

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Last Updated: August 24, 2012
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