Division of Cancer Control & Population Sciences

Grant Details

Grant Number:	7R01CA079060-06 Interpret this number
Primary Investigator:	Lipshultz, Steven
Organization:	University Of Miami School Of Medicine
Project Title:	Cardiac Risk Factors in Pediatric Cancer Survivors
Fiscal Year:	2002

Abstract

An abstract does not currently exist for this grant

Publications

Exercise capacity in long-term survivors of pediatric cancer: an analysis from the Cardiac Risk Factors in Childhood Cancer Survivors Study.
Authors: Miller AM, Lopez-Mitnik G, Somarriba G, Lipsitz SR, Hinkle AS, Constine LS, Lipshultz SE, Miller TL
Source: Pediatr Blood Cancer, 2013 Apr;60(4), p. 663-8.
EPub date: 2012 Dec 19.
PMID: 23255294
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NCI NIH HHS - CA68484	NCRR NIH HHS - M01RR00044
NCI NIH HHS - CA127642

MeSH Terms:

Young Adult	Ventricular Function, Left	Humans
Physical Fitness	Child	Exercise Test
Cross-Sectional Studies	Neoplasms	Oxygen Consumption
Risk Factors	Adult	Cardiovascular Diseases
Adolescent	Time Factors	Survivors
Female	Male	Myocardium

Cranial irradiation as an additional risk factor for anthracycline cardiotoxicity in childhood cancer survivors: an analysis from the cardiac risk factors in childhood cancer survivors study.
Authors: Landy DC, Miller TL, Lipsitz SR, Lopez-Mitnik G, Hinkle AS, Constine LS, Adams MJ, Lipshultz SE
Source: Pediatr Cardiol, 2013 Apr;34(4), p. 826-34.
EPub date: 2012 Oct 19.
PMID: 23080542
Related Citations

Grant Numbers:

NHLBI NIH HHS - HL087708	NICHD NIH HHS - HD052104	NICHD NIH HHS - HD052102
NHLBI NIH HHS - HL087000	NICHD NIH HHS - HD80002	NHLBI NIH HHS - HL007188
NHLBI NIH HHS - HL095127	NCI NIH HHS - CA127642	NCI NIH HHS - CA068484
NHLBI NIH HHS - HL079233	NCI NIH HHS - CA79060	NHLBI NIH HHS - HL072705
NHLBI NIH HHS - HL078522	NIAID NIH HHS - AI50274	NHLBI NIH HHS - HL094100
NHLBI NIH HHS - HL053392	NHLBI NIH HHS - HL004537

Anthracycline associated cardiotoxicity in survivors of childhood cancer.
Authors: Lipshultz SE, Alvarez JA, Scully RE
Source: Heart, 2008 Apr;94(4), p. 525-33.
PMID: 18347383
Related Citations

Grant Numbers:

NCI NIH HHS - CA34183-SL	NHLBI NIH HHS - HL69800-SL	NHLBI NIH HHS - HL59837-SL
NCI NIH HHS - CA79060-SL	NHLBI NIH HHS - HL53392-SL	NCI NIH HHS - CA06516-SL
NCI NIH HHS - CA127642-SL	NCI NIH HHS - CA68484-SL

MeSH Terms:

Neoplasms	Anthracyclines	Heart Diseases
Dose-Response Relationship, Drug	Antineoplastic Agents	Risk Factors
Humans	Child	Male
Female	Child, Preschool

Anthracycline cardiotoxicity in long-term survivors of childhood cancer.
Authors: Scully RE, Lipshultz SE
Source: Cardiovasc Toxicol, 2007;7(2), p. 122-8.
PMID: 17652816
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL69800	NHLBI NIH HHS - HL59837	NCI NIH HHS - CA34183
NCI NIH HHS - CA06516

MeSH Terms:

Neoplasms	Anthracyclines	Heart Diseases
Humans	Disease Progression	Child
Monitoring, Physiologic	Antibiotics, Antineoplastic	Survivors
Signal Transduction

Anthracycline-induced cardiotoxicity: course, pathophysiology, prevention and management.
Authors: Barry E, Alvarez JA, Scully RE, Miller TL, Lipshultz SE
Source: Expert Opin Pharmacother, 2007 Jun;8(8), p. 1039-58.
PMID: 17516870
Related Citations

Grant Numbers:

NCI NIH HHS - CA34183-SL	NHLBI NIH HHS - HL69800-SL	NHLBI NIH HHS - HL59837-SL
NCI NIH HHS - CA79060-SL	NHLBI NIH HHS - HL53392-SL	NCI NIH HHS - CA06516-SL
NCI NIH HHS - CA68484-SL

MeSH Terms:

Heart	Neoplasms	Drug Interactions
Anthracyclines	Heart Diseases	Risk Factors
Humans	Drug Monitoring	Cardiovascular Agents
Antibiotics, Antineoplastic	Razoxane

Long-term effects of treatments for childhood cancers.
Authors: Alvarez JA, Scully RE, Miller TL, Armstrong FD, Constine LS, Friedman DL, Lipshultz SE
Source: Curr Opin Pediatr, 2007 Feb;19(1), p. 23-31.
PMID: 17224658
Related Citations

Grant Numbers:

NCI NIH HHS - CA34183-SL	NHLBI NIH HHS - HL69800-SL	NIDA NIH HHS - 90DD0408-DA
NHLBI NIH HHS - HL59837-SL	NCI NIH HHS - CA79060-SL	NIDA NIH HHS - 5 U54 L07058-DA
NHLBI NIH HHS - HL53392-SL	NCI NIH HHS - CA06516-SL	NHLBI NIH HHS - HL48012
NCI NIH HHS - U10-CA30969-DA	NIDA NIH HHS - MCJ-129147-05-05-DA	NCI NIH HHS - CA68484-SL

MeSH Terms:

Disease-Free Survival	Antineoplastic Agents	Humans
Endocrine System Diseases	Child	Cognition Disorders
Anthracyclines	Neoplasms	Time
Cardiovascular Diseases	Adolescent	Female
Male

Incidence, causes, and outcomes of dilated cardiomyopathy in children.
Authors: Towbin JA, Lowe AM, Colan SD, Sleeper LA, Orav EJ, Clunie S, Messere J, Cox GF, Lurie PR, Hsu D, Canter C, Wilkinson JD, Lipshultz SE
Source: JAMA, 2006 Oct 18;296(15), p. 1867-76.
PMID: 17047217
Related Citations

Grant Numbers:

NCI NIH HHS - R01 CA79060	NHLBI NIH HHS - R01 HL72705	NHLBI NIH HHS - R01 HL53392
NHLBI NIH HHS - P01 HL67155	NHLBI NIH HHS - R01 HL78522	NCI NIH HHS - P01 CA68484
NHLBI NIH HHS - N01 HR96041

MeSH Terms:

United States	Heart Transplantation	Humans
Cardiomyopathy, Dilated	Disease Progression	Child
Longitudinal Studies	Child, Preschool	Registries
Infant	Canada	Risk Factors
Incidence	Adolescent	Female
Male	Survival Analysis

Factors associated with establishing a causal diagnosis for children with cardiomyopathy.
Authors: Cox GF, Sleeper LA, Lowe AM, Towbin JA, Colan SD, Orav EJ, Lurie PR, Messere JE, Wilkinson JD, Lipshultz SE
Source: Pediatrics, 2006 Oct;118(4), p. 1519-31.
PMID: 17015543
Related Citations

Grant Numbers:

NCI NIH HHS - R01 CA79060	NHLBI NIH HHS - R01 HL72705	NHLBI NIH HHS - R01 HL53392
NHLBI NIH HHS - P01 HL67155	NHLBI NIH HHS - R01 HL78522	NCI NIH HHS - P01 CA68484
NHLBI NIH HHS - N01 HR96041

MeSH Terms:

Causality	Diagnosis, Differential	Humans
Echocardiography	Retrospective Studies	Prognosis
Biopsy	Child	Muscle, Skeletal
Child, Preschool	Medical History Taking	Registries
Infant	Myocarditis	Female
Male	Myocardium

Frequency of clinically unsuspected myocardial injury at a children's hospital.
Authors: Lipshultz SE, Wong JC, Lipsitz SR, Simbre VC 2nd, Zareba KM, Galpechian V, Rifai N
Source: Am Heart J, 2006 Apr;151(4), p. 916-22.
PMID: 16569563
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL69800	NHLBI NIH HHS - HL59837	NCI NIH HHS - CA34183
NCI NIH HHS - CA06516	NHLBI NIH HHS - HL48012

MeSH Terms:

Troponin T	Humans	Myoglobin
Pilot Projects	Boston	Child
Cardiomyopathies	Child, Preschool	Infant
Creatine Kinase	Adult	Hospitals, Private
Creatine Kinase, MB Form	Troponin I	Adolescent
Myocytes, Cardiac	Male	Female
Immunoenzyme Techniques

Impact of HIV and highly active antiretroviral therapy on leukocyte adhesion molecules, arterial inflammation, dyslipidemia, and atherosclerosis.
Authors: Fisher SD, Miller TL, Lipshultz SE
Source: Atherosclerosis, 2006 Mar;185(1), p. 1-11.
EPub date: 2005 Nov 16.
PMID: 16297390
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL69800	NHLBI NIH HHS - HL59837

MeSH Terms:

Atherosclerosis	HIV Protease Inhibitors	HIV Infections
Humans	Treatment Outcome	Antiretroviral Therapy, Highly Active
Arteritis	Cell Adhesion Molecules	Dyslipidemias
Reverse Transcriptase Inhibitors

Cardiac changes associated with growth hormone therapy among children treated with anthracyclines.
Authors: Lipshultz SE, Vlach SA, Lipsitz SR, Sallan SE, Schwartz ML, Colan SD
Source: Pediatrics, 2005 Jun;115(6), p. 1613-22.
PMID: 15930224
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL69800	NHLBI NIH HHS - HL59837

MeSH Terms:

Hypertrophy, Left Ventricular	Precursor Cell Lymphoblastic Leukemia-Lymphoma	Body Height
Human Growth Hormone	Humans	Hemodynamics
Child	Cardiovascular Agents	Child, Preschool
Infant	Anthracyclines	Enalapril
Hypopituitarism	Myocardial Contraction	Antineoplastic Combined Chemotherapy Protocols
Ventricular Dysfunction, Left	Angiotensin-Converting Enzyme Inhibitors	Adolescent
Survivors	Male	Female
Heart Ventricles

Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia.
Authors: Lipshultz SE, Lipsitz SR, Sallan SE, Dalton VM, Mone SM, Gelber RD, Colan SD
Source: J Clin Oncol, 2005 Apr 20;23(12), p. 2629-36.
PMID: 15837978
Related Citations

Grant Numbers:

NHLBI NIH HHS - HL 59837	NHLBI NIH HHS - HL 53392	NHLBI NIH HHS - HL 69800
NCI NIH HHS - CA79060	NHLBI NIH HHS - HR 96041	NCI NIH HHS - CA 68484
NCI NIH HHS - CA 55576	NCI NIH HHS - CA06516	NHLBI NIH HHS - HL 72705

MeSH Terms:

Precursor Cell Lymphoblastic Leukemia-Lymphoma	Heart Diseases	Blood Pressure
Humans	Child	Antibiotics, Antineoplastic
Longitudinal Studies	Morbidity	Doxorubicin
Child, Preschool	Infant	Adult
Ventricular Dysfunction, Left	Adolescent	Time Factors
Female	Male

Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy.
Authors: Adams MJ, Lipsitz SR, Colan SD, Tarbell NJ, Treves ST, Diller L, Greenbaum N, Mauch P, Lipshultz SE
Source: J Clin Oncol, 2004 Aug 1;22(15), p. 3139-48.
PMID: 15284266
Related Citations

Grant Numbers:

NCRR NIH HHS - RRO2172	NCI NIH HHS - CA79060	NHLBI NIH HHS - HL04161
NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484	NHLBI NIH HHS - HL07937
NHLBI NIH HHS - HL59837	NHLBI NIH HHS - HL70930

MeSH Terms:

Heart Conduction System	Tachycardia	Humans
Echocardiography	Quality of Life	Cardiovascular System
Child	Mediastinum	Heart Valve Diseases
Cardiomyopathy, Restrictive	Exercise Test	Heart Rate
Radiotherapy Dosage	Electrocardiography	Heart Block
Adult	Thorax	Adolescent
Time Factors	Hodgkin Disease	Male
Female

Cardiovascular risk factors, monitoring, and therapy for HIV-infected patients.
Authors: Lipshultz SE, Fisher SD, Lai WW, Miller TL
Source: AIDS, 2003 Apr;17 Suppl 1, p. S96-122.
PMID: 12870537
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL07937	NICHD NIH HHS - HD34568	NHLBI NIH HHS - HL59837

MeSH Terms:

Anti-Infective Agents	Heart Diseases	Electrocardiography, Ambulatory
Echocardiography, Stress	Lipids	Humans
Cardiac Catheterization	Echocardiography	Tomography, X-Ray Computed
Biopsy	Physical Examination	Risk Assessment
Coronary Disease	Genetic Testing	HIV Infections
Cytokines	Cardiovascular Diseases	Biological Markers

The incidence of pediatric cardiomyopathy in two regions of the United States.
Authors: Lipshultz SE, Sleeper LA, Towbin JA, Lowe AM, Orav EJ, Cox GF, Lurie PR, McCoy KL, McDonald MA, Messere JE, Colan SD
Source: N Engl J Med, 2003 Apr 24;348(17), p. 1647-55.
PMID: 12711739
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NCI NIH HHS - CA55576	NHLBI NIH HHS - HL53392
NCI NIH HHS - CA68484

MeSH Terms:

Humans	Child	Cardiomyopathies
Age Distribution	Child, Preschool	Registries
Infant	Oklahoma	Prospective Studies
New England	Incidence	Adolescent
Sex Distribution	Southwestern United States	Female
Male

Cardiovascular monitoring and therapy for HIV-infected patients.
Authors: Lipshultz SE, Fisher SD, Lai WW, Miller TL
Source: Ann N Y Acad Sci, 2001 Nov;946, p. 236-73.
PMID: 11762991
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060	NHLBI NIH HHS - HL53392	NCI NIH HHS - CA68484
NHLBI NIH HHS - HL07937	NICHD NIH HHS - HD34568	NHLBI NIH HHS - HL59837

MeSH Terms:

HIV Infections	Humans	Cardiovascular Diseases
Monitoring, Physiologic

Epidemiology of anthracycline cardiotoxicity in children and adults.
Authors: Grenier MA, Lipshultz SE
Source: Semin Oncol, 1998 Aug;25(4 Suppl 10), p. 72-85.
PMID: 9768828
Related Citations

Grant Numbers:

NCI NIH HHS - CA79060

NHLBI NIH HHS - HL53392

NCI NIH HHS - CA68484

MeSH Terms:

Anthracyclines	Heart Diseases	Antineoplastic Agents
Risk Factors	Humans	Adult
Child	Male	Female