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Grant Details

Grant Number: 5R01CA100810-03 Interpret this number
Primary Investigator: Moyer, Anne
Organization: State University New York Stony Brook
Project Title: Review of Psychosocial Interventions for Cancer
Fiscal Year: 2006
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Abstract

DESCRIPTION (provided by applicant): Cancer is greatly feared, difficult and complex to manage, and costly--both emotionally and financially. An estimated 7.1 million Americans have been diagnosed with cancer in the past 20 years and have had to face coping with the disease, its treatment, and living with its aftermath. Advances in cancer treatment have brought psychosocial challenges for patients such as increased involvement in treatment decisions, coping with side effects, and living as cancer survivors. Accordingly, more attention is currently paid to the quality of life of individuals with cancer. The rapid growth of inquiry in this area makes the systematic review of this research important and timely. The proposed project aims to address key questions regarding psychosocial interventions for cancer patients using systematic and meta-analytic review techniques. These techniques are useful in making sense of accumulated study findings and in identifying remaining research questions. The specific goals are (1) to elucidate the mechanisms by which psychosocial interventions for cancer patients may foster improvements in quality of life; (2) to determine the effects of specific treatment ingredients comprising interventions for individuals coping with cancer; (3) to clarify mixed results regarding the effects of psychosocial interventions on length of survival in individuals with cancer; (4) to determine if previously-documented benefits of psychosocial interventions tested in randomized (efficacy) trials hold for non-randomized (effectiveness) trials delivered in community settings; and (5) to identify which populations and types of interventions have been thoroughly studied and which have been overlooked. A thorough survey of the published and unpublished literature will be undertaken. A number of different channels will be used to ensure an exhaustive search. Each eligible study will be coded with respect to a number of features related to: the setting of the study, participants, methodology, and characteristics of the intervention. Coding procedures will be rigorously developed and maintained to maximize validity and reliability. Study outcomes will be expressed in terms of effect sizes, a standardized metric that allows aggregation of the magnitude and direction of results across studies. Where appropriate, moderator analyses of the influence of study level variables on outcomes will be performed. Integration and reevaluation of this work will help us to understand how psychosocial interventions work and how they can be improved.

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Publications

Mediators of change in psychosocial interventions for cancer patients: a systematic review.
Authors: Moyer A, Goldenberg M, Hall MA, Knapp-Oliver SK, Sohl SJ, Sarma EA, Schneider S
Source: Behav Med, 2012;38(3), p. 90-114.
PMID: 22873734
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Lessons to be learned from 25 years of research investigating psychosocial interventions for cancer patients.
Authors: Moyer A, Knapp-Oliver SK, Sohl SJ, Schnieder S, Floyd AH
Source: Cancer J, 2009 Sep-Oct;15(5), p. 345-51.
PMID: 19826351
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Pre-intervention distress moderates the efficacy of psychosocial treatment for cancer patients: a meta-analysis.
Authors: Schneider S, Moyer A, Knapp-Oliver S, Sohl S, Cannella D, Targhetta V
Source: J Behav Med, 2010 Feb;33(1), p. 1-14.
EPub date: 2009 Sep 27.
PMID: 19784868
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Emotional distress following genetic testing for hereditary breast and ovarian cancer: a meta-analytic review.
Authors: Hamilton JG, Lobel M, Moyer A
Source: Health Psychol, 2009 Jul;28(4), p. 510-8.
PMID: 19594276
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Group vs. individual exercise interventions for women with breast cancer: a meta-analysis.
Authors: Floyd A, Moyer A
Source: Health Psychol Rev, 2009 May 1;4(1), p. 22-41.
PMID: 20607139
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Published versus unpublished dissertations in psycho-oncology intervention research.
Authors: Moyer A, Schneider S, Knapp-Oliver SK, Sohl SJ
Source: Psychooncology, 2010 Mar;19(3), p. 313-7.
PMID: 19353515
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Characteristics and methodological quality of 25 years of research investigating psychosocial interventions for cancer patients.
Authors: Moyer A, Sohl SJ, Knapp-Oliver SK, Schneider S
Source: Cancer Treat Rev, 2009 Aug;35(5), p. 475-84.
EPub date: 2009 Mar 4.
PMID: 19264411
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Tailored interventions to promote mammography screening: a meta-analytic review.
Authors: Sohl SJ, Moyer A
Source: Prev Med, 2007 Oct;45(4), p. 252-61.
EPub date: 2007 Jun 23.
PMID: 17643481
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Surgical treatment preferences in Chinese-American women with early-stage breast cancer.
Authors: Killoran M, Moyer A
Source: Psychooncology, 2006 Nov;15(11), p. 969-84.
PMID: 16470910
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