|Grant Number:||5R01CA096095-05 Interpret this number|
|Primary Investigator:||Lanier, Anne|
|Organization:||Alaska Native Tribal Health Consortium|
|Project Title:||A Prospective Study of Alaska Natives & American Indians|
DESCRIPTION: (Provided by applicant) Rates of chronic diseases vary substantially between American Indians and Alaska Natives (AIANs) and U.S. white populations for reasons that are largely unknown. Although little is known about factors that affect chronic diseases in AIANs, incidence rates for most chronic diseases are increasing. This 4-year proposal focuses on the development of an AIAN cohort to obtain a better understanding of the disparity in disease rates and risk factor knowledge that exist between AIANs and U.S. white populations. The purpose of this proposal is to develop valid and reliable methods to obtain diet, physical activity, and lifestyle information and to determine the most efficient and effective ways to recruit, enroll, and track study participants from diverse populations. We will work with local communities to develop culturally appropriate questionnaires that will accurately capture dietary intake, physical activity patterns lifestyle and cultural habits. We will work with local health providers and the Indian Health Service to access relevant study-related data from medical records and we will establish population-based recruitment methods. Starting in year 3 of the proposal, we will initiate recruitment and data collection, testing various protocols to determine the most efficient and effective way to conduct the study. We project that 2000 Alaska Natives, 3000 American Indians from the Navajo Nation, and 1500 American Indians from the Plains states will be enrolled over a 24-month time period. This number of participants is needed to adequately test our ability to enroll large numbers of individuals as well as determine potential burden to clinics as a result of enrollment. The major scientific goal of the AIAN cohort is to determine how diet, physical activity, and other lifestyle and cultural factors relate to the development and progression of chronic diseases such as cancer, cardiovascular disease, stroke, Type 2 diabetes, chronic lung and respiratory diseases, and related mortality from these diseases. Study data will be used to assess health status and identify groups of the population at risk for various health conditions. Longitudinal data will be used to identify factors that contribute to health and prevent disease. The AIAN cohort will serve as a resource to enhance research and training activities of AIAN students interested in health research, health education, and general public health.
Sex differences in obesity prevalence and cardiometabolic factors among Western Alaska Native people.
Authors: Hopkins SE, Austin MA, Metzger JS, Koller KR, Umans JG, Kaufmann C, Wolfe AW, Howard BV, Boyer BB
Source: Nutr Metab Cardiovasc Dis, 2015 Mar;25(3), p. 312-8.
EPub date: 2014 Oct 29.
Utilizing harmonization and common surveillance methods to consolidate 4 cohorts: the Western Alaska Tribal Collaborative for Health (WATCH) study.
Authors: Koller KR, Wolfe AW, Metzger JS, Austin MA, Hopkins SE, Kaufmann C, Jolly SE, Ebbesson SO, Umans JG, Howard BV, Boyer BB
Source: Int J Circumpolar Health, 2013;72, p. null.
EPub date: 2013 May 2.
Reproductive cancer risk factors among Alaska Native women: the Alaska Education and Research Towards Health (EARTH) Study.
Authors: Redwood DG, Lanier AP, Johnston JM, Murphy N, Murtaugh MA
Source: Womens Health Issues, 2012 Jul-Aug;22(4), p. e387-93.
EPub date: 2012 May 18.
Occupational and environmental exposures among Alaska Native and American Indian people living in Alaska and the Southwest United States.
Authors: Redwood D, Lanier AP, Brubaker M, Orell L, Tom-Orme L, George C, Edwards S, Slattery M
Source: J Environ Health, 2012 May;74(9), p. 22-8.
The Alaska Education and Research Towards Health (EARTH) Study: cancer risk factors.
Authors: Lanier AP, Redwood DG, Kelly JJ
Source: J Cancer Educ, 2012 Apr;27(1 Suppl), p. S80-5.
Prevalence of fracture and osteoporosis risk factors in American Indian and Alaska Native people.
Authors: Frech T, Ma KN, Ferrucci ED, Lanier AP, McFadden M, Tom-Orme L, Slattery ML, Murtaugh MA
Source: J Health Care Poor Underserved, 2012 Aug;23(3), p. 1157-73.
Depression prevalence and associated factors among Alaska Native people: the Alaska education and research toward health (EARTH) study.
Authors: Dillard DA, Smith JJ, Ferucci ED, Lanier AP
Source: J Affect Disord, 2012 Feb;136(3), p. 1088-97.
EPub date: 2011 Dec 3.
Self-reported asthma among American Indian and Alaska Native people in Alaska.
Authors: Orell LJ, Ferucci ED, Lanier AP, Etzel RA
Source: J Health Care Poor Underserved, 2011 Nov;22(4), p. 1264-78.
Validation of a dietary history questionnaire for American Indian and Alaska Native people.
Authors: Murtaugh MA, Ma KN, Greene T, Redwood D, Edwards S, Johnson J, Tom-Orme L, Lanier AP, Henderson JA, Slattery ML
Source: Ethn Dis, 2010 Autumn;20(4), p. 429-36.
Chronic disease risk factors among Alaska Native and American Indian people, Alaska, 2004-2006.
Authors: Redwood DG, Lanier AP, Johnston JM, Asay ED, Slattery ML
Source: Prev Chronic Dis, 2010 Jul;7(4), p. A85.
EPub date: 2010 Jun 15.
Tobacco use among Alaska Native people in the EARTH study.
Authors: Smith JJ, Ferucci ED, Dillard DA, Lanier AP
Source: Nicotine Tob Res, 2010 Aug;12(8), p. 839-44.
EPub date: 2010 Jun 13.
Differences in cigarette and smokeless tobacco use among American Indian and Alaska Native people living in Alaska and the Southwest United States.
Authors: Redwood D, Lanier AP, Renner C, Smith J, Tom-Orme L, Slattery ML
Source: Nicotine Tob Res, 2010 Jul;12(7), p. 791-6.
EPub date: 2010 Jun 4.
Associations among body mass index, waist circumference, and health indicators in American Indian and Alaska Native adults.
Authors: Slattery ML, Ferucci ED, Murtaugh MA, Edwards S, Ma KN, Etzel RA, Tom-Orme L, Lanier AP
Source: Am J Health Promot, 2010 Mar-Apr;24(4), p. 246-54.
Family health history and health behaviors in Alaska native and American Indian people.
Authors: Slattery ML, Murtaugh MA, Lanier AP, Ma KN, Ferucci ED, Etzel RA, Edwards S
Source: J Health Care Poor Underserved, 2009 Aug;20(3), p. 678-94.
Physical activity patterns of American Indian and Alaskan Native people living in Alaska and the Southwestern United States.
Authors: Redwood D, Schumacher MC, Lanier AP, Ferucci ED, Asay E, Helzer LJ, Tom-Orme L, Edwards SL, Murtaugh MA, Slattery ML
Source: Am J Health Promot, 2009 Jul-Aug;23(6), p. 388-95.
Safety behaviours among Alaskan Native and American Indian people living in Alaska.
Authors: Redwood DG, Hagan KD, Perkins RD, Stafford HB, Orell LJ, Lanier AP
Source: Inj Prev, 2009 Feb;15(1), p. 30-5.
Metabolic syndrome: prevalence among American Indian and Alaska native people living in the southwestern United States and in Alaska.
Authors: Schumacher C, Ferucci ED, Lanier AP, Slattery ML, Schraer CD, Raymer TW, Dillard D, Murtaugh MA, Tom-Orme L
Source: Metab Syndr Relat Disord, 2008 Dec;6(4), p. 267-73.
Traditional foods and physical activity patterns and associations with cultural factors in a diverse Alaska Native population.
Authors: Redwood DG, Ferucci ED, Schumacher MC, Johnson JS, Lanier AP, Helzer LJ, Tom-Orme L, Murtough MA, Slattery ML
Source: Int J Circumpolar Health, 2008 Sep;67(4), p. 335-48.
Prevalence and predictors of cancer screening among American Indian and Alaska native people: the EARTH study.
Authors: Schumacher MC, Slattery ML, Lanier AP, Ma KN, Edwards S, Ferucci ED, Tom-Orme L
Source: Cancer Causes Control, 2008 Sep;19(7), p. 725-37.
EPub date: 2008 Feb 29.
Development, implementation, and evaluation of a computerized self-administered diet history questionnaire for use in studies of American Indian and Alaskan native people.
Authors: Slattery ML, Murtaugh MA, Schumacher MC, Johnson J, Edwards S, Edwards R, Benson J, Tom-Orme L, Lanier AP
Source: J Am Diet Assoc, 2008 Jan;108(1), p. 101-9.
A prospective cohort of American Indian and Alaska Native people: study design, methods, and implementation.
Authors: Slattery ML, Schumacher MC, Lanier AP, Edwards S, Edwards R, Murtaugh MA, Sandidge J, Day GE, Kaufman D, Kanekar S, Tom-Orme L, Henderson JA
Source: Am J Epidemiol, 2007 Sep 1;166(5), p. 606-15.
EPub date: 2007 Jun 22.