Grant Details
| Grant Number: | 5P50CA084724-05 Interpret this number |
| Primary Investigator: | Fiore, Michael |
| Organization: | University Of Wisconsin-Madison |
| Project Title: | RELAPSE: Linking Science and Practice |
| Fiscal Year: | 2003 |
Abstract
DESCRIPTION: (Applicant's Description) This TTURC proposal targets relapse to tobacco use. The justification for this concentration is that relapse is the central, unanswered challenge to tobacco researchers today: no effective relapse prevention programs exist and relapse consistently claims the majority of smokers who achieve abstinence. This TTURC proposal describes a transdisciplinary effort to uncover new and important information relevant to tobacco control, achieve wide-spread dissemination and use of such information, sow the seeds for future innovative and transdisciplinary tobacco research, encourage new researchers from diverse backgrounds to enter the field of tobacco science, and to facilitate their training. In sum, the over-arching goals are to create and foster new and integrative research in tobacco control, attract outstanding students and scientists into the field of tobacco research, and train them to become outstanding tobacco scientists. The TTURC will achieve its goals through the conduct of three large research projects, a pilot grant research program, a transdisciplinary career development program, and an administrative core. One of the large research projects will develop a novel, computerized relapse prevention strategy, the second will develop a new measure of tobacco dependence and relate it to relapse, and the third will use real-time recording to study how treatment affects relapse likelihood. The pilot grant program will support innovative and promising studies relevant to relapse prevention, and will actively offer collaborative opportunities and support to outstanding scientists who are new to tobacco research. The career development program is designed to attract individuals from diverse backgrounds and train them in state-of-the-art tobacco science. All of these elements reflect three central themes of characteristics: they are: transdisciplinary, they are focused on relapse, and the different perspectives and data yielded by the transdisciplinary approach will be integrated to achieve a deeper understanding of relapse and relapse prevention. Transdisciplinary contributions will be promoted by involving a wide range of individuals, launching research projects that require novel or innovative collaborations, and by building in structures that prompt and reinforce breadth in research and training activities.
Publications
Do smokers know what we're talking about? The construct validity of nicotine dependence questionnaire measures.
Authors: Japuntich SJ, Piper ME, Schlam TR, Bolt DM, Baker TB
Source: Psychol Assess, 2009 Dec;21(4), p. 595-607.
PMID: 19947792
Related Citations
Grant Numbers:
| NCRR NIH HHS - 1KL2RR025012-01 | NIDA NIH HHS - P50 DA019706-08 | NIDA NIH HHS - P50 DA019706-06 |
| NCI NIH HHS - P50 CA084724-05 | NIDA NIH HHS - DA0197-06 | NCI NIH HHS - K05 CA139871 |
| NCI NIH HHS - CA84724-05 | NCI NIH HHS - 1K05CA139871 |
MeSH Terms:
Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.
Authors: Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS
Source: Nicotine Tob Res, 2009 Jul;11(7), p. 785-96.
EPub date: 2009 May 12.
PMID: 19436041
Related Citations
Grant Numbers:
| NCI NIH HHS - P50-CA84724 | NHLBI NIH HHS - N01-HR46014 | PHS HHS - P50-84178 |
| NHLBI NIH HHS - P01-HL72903 | NIDA NIH HHS - P50-DA0197 |
MeSH Terms:
The Wisconsin Predicting Patients' Relapse questionnaire.
Authors: Bolt DM, Piper ME, McCarthy DE, Japuntich SJ, Fiore MC, Smith SS, Baker TB
Source: Nicotine Tob Res, 2009 May;11(5), p. 481-92.
EPub date: 2009 Apr 16.
PMID: 19372573
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724 | NCRR NIH HHS - 1KL2-RR025012-01 |
MeSH Terms:
| Smoking | Questionnaires | Placebo Effect |
| Double-Blind Method | Humans | Smoking Cessation |
| Adult | Predictive Value of Tests | Wisconsin |
| Recurrence | Male | Female |
Time to first cigarette in the morning as an index of ability to quit smoking: implications for nicotine dependence.
Authors: Transdisciplinary Tobacco Use Research Center (TTURC) Tobacco Dependence, Baker TB, Piper ME, McCarthy DE, Bolt DM, Smith SS, Kim SY, Colby S, Conti D, Giovino GA, Hatsukami D, Hyland A, Krishnan-Sarin S, Niaura R, Perkins KA, Toll BA
Source: Nicotine Tob Res, 2007 Nov;9 Suppl 4, p. S555-70.
PMID: 18067032
Related Citations
Grant Numbers:
| NIDA NIH HHS - R01 DA016737-05 | NCI NIH HHS - P50 CA084735-06 | NCI NIH HHS - P50 CA084719-06 |
| NCI NIH HHS - P50 CA084724-050003 | NIDA NIH HHS - P50-DA13334 | NIDA NIH HHS - P50 DA019706-06 |
| NIDA NIH HHS - P50 DA013333-06 | NIDA NIH HHS - P50-DA0197-06 | NCI NIH HHS - P50-CA084735-06 |
| NCI NIH HHS - P50 CA084719 | NCI NIH HHS - P50-CA111236 | NCI NIH HHS - P50 CA084719-060003 |
| NIDA NIH HHS - R01-DA016737 | NCI NIH HHS - P50-DA/CA84718 | NIAAA NIH HHS - P50-AA15632 |
| NIDA NIH HHS - P50 DA013334-02 | NCI NIH HHS - P50-CA84724-05 | NIAAA NIH HHS - P50 AA015632-06 |
| NIDA NIH HHS - K12-DA00167 | NCI NIH HHS - P50 CA084724-05 | NIDA NIH HHS - P50-DA013333 |
| NCI NIH HHS - P50-CA084719 | NIDA NIH HHS - P50 DA013333 |
MeSH Terms:
| Demography | Smoking | Models, Psychological |
| Motivation | Tobacco Use Disorder | Humans |
| Smoking Cessation | Time Factors | Recurrence |
| Population Surveillance |
A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
Authors: Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF
Source: PLoS Genet, 2008 Jul 11;4(7), p. e1000125.
EPub date: 2008 Jul 11.
PMID: 18618000
Related Citations
Grant Numbers:
| NIDA NIH HHS - P50-DA19706 | NCI NIH HHS - P50-CA84724 | NHLBI NIH HHS - N01-HR46014 |
| NHLBI NIH HHS - P01-HL72903 |
MeSH Terms:
Assessing dimensions of nicotine dependence: an evaluation of the Nicotine Dependence Syndrome Scale (NDSS) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM).
Authors: Piper ME, McCarthy DE, Bolt DM, Smith SS, Lerman C, Benowitz N, Fiore MC, Baker TB
Source: Nicotine Tob Res, 2008 Jun;10(6), p. 1009-20.
PMID: 18584464
Related Citations
Grant Numbers:
| NIDA NIH HHS - P50 DA019706-06 | NCI NIH HHS - P50-CA84724-05 | NIDA NIH HHS - P50-DA0197-06 |
| NCI NIH HHS - CA/DA P 50-84178 | NCI NIH HHS - K05 CA139871 |
MeSH Terms:
Efficacy of bupropion alone and in combination with nicotine gum.
Authors: Piper ME, Federman EB, McCarthy DE, Bolt DM, Smith SS, Fiore MC, Baker TB
Source: Nicotine Tob Res, 2007 Sep;9(9), p. 947-54.
PMID: 17763111
Related Citations
Grant Numbers:
| NCI NIH HHS - P50 CA084724-050003 | NIDA NIH HHS - P50 DA019706-06 | NIDA NIH HHS - DA0197-06 |
| NCI NIH HHS - CA84724-05 |
MeSH Terms:
Urban poverty and infant mortality rate disparities.
Authors: Sims M, Sims TL, Bruce MA
Source: J Natl Med Assoc, 2007 Apr;99(4), p. 349-56.
PMID: 17444423
Related Citations
Grant Numbers:
| NIAAA NIH HHS - 1R01 AA12522 | NCI NIH HHS - 1 P50 CA84724 | NIMHD NIH HHS - 5 P20 MD000516-03 |
MeSH Terms:
Sex differences in negative affective response during nicotine withdrawal.
Authors: Hogle JM, Curtin JJ
Source: Psychophysiology, 2006 Jul;43(4), p. 344-56.
PMID: 16916430
Related Citations
Grant Numbers:
| NCI NIH HHS - P50 CA84724 |
MeSH Terms:
| Hydrocortisone | Substance Withdrawal Syndrome | Startle Reaction |
| Fear | Sex Characteristics | Tobacco Use Disorder |
| Humans | Smoking | Adult |
| Smoking Cessation | Affect | Electroshock |
| Female | Male |
Assessing tobacco dependence: a guide to measure evaluation and selection.
Authors: Piper ME, McCarthy DE, Baker TB
Source: Nicotine Tob Res, 2006 Jun;8(3), p. 339-51.
PMID: 16801292
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724 | NIDA NIH HHS - DA19706 |
MeSH Terms:
Tobacco withdrawal and negative affect: an analysis of initial emotional response intensity and voluntary emotion regulation.
Authors: Piper ME, Curtin JJ
Source: J Abnorm Psychol, 2006 Feb;115(1), p. 96-102.
PMID: 16492100
Related Citations
Grant Numbers:
| NCI NIH HHS - P50 CA84724 |
MeSH Terms:
| Severity of Illness Index | Volition | Substance Withdrawal Syndrome |
| Questionnaires | Humans | Social Control, Informal |
| Adult | Tobacco | Mood Disorders |
| Male | Female |
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking.
Authors: Cannon DS, Baker TB, Piper ME, Scholand MB, Lawrence DL, Drayna DT, McMahon WM, Villegas GM, Caton TC, Coon H, Leppert MF
Source: Nicotine Tob Res, 2005 Dec;7(6), p. 853-8.
PMID: 16298720
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724 |
MeSH Terms:
A multiple motives approach to tobacco dependence: the Wisconsin Inventory of Smoking Dependence Motives (WISDM-68).
Authors: Piper ME, Piasecki TM, Federman EB, Bolt DM, Smith SS, Fiore MC, Baker TB
Source: J Consult Clin Psychol, 2004 Apr;72(2), p. 139-54.
PMID: 15065950
Related Citations
Grant Numbers:
| NCI NIH HHS - P50-CA84724 |
MeSH Terms:
| Smoking | Questionnaires | Reproducibility of Results |
| Motivation | Tobacco Use Disorder | Humans |
Integrating smoking cessation treatment into primary care: an effectiveness study.
Authors: Fiore MC, McCarthy DE, Jackson TC, Zehner ME, Jorenby DE, Mielke M, Smith SS, Guiliani TA, Baker TB
Source: Prev Med, 2004 Apr;38(4), p. 412-20.
PMID: 15020174
Related Citations
Grant Numbers:
| NCI NIH HHS - 1 R01 CA71377 | NCI NIH HHS - 1 P50 CA84724 |
MeSH Terms:
Addiction motivation reformulated: an affective processing model of negative reinforcement.
Authors: Baker TB, Piper ME, McCarthy DE, Majeskie MR, Fiore MC
Source: Psychol Rev, 2004 Jan;111(1), p. 33-51.
PMID: 14756584
Related Citations
Grant Numbers:
| NCI NIH HHS - 1 P50 CA84724 |
MeSH Terms:
Motivational influences on cigarette smoking.
Authors: Baker TB, Brandon TH, Chassin L
Source: Annu Rev Psychol, 2004;55, p. 463-91.
PMID: 14744223
Related Citations
Grant Numbers:
| NCI NIH HHS - R01CA80706 | NIDA NIH HHS - DA05227 | NCI NIH HHS - P50 CA84724 |
| NCI NIH HHS - R01 CA94256 | NIDA NIH HHS - DA13555 |
MeSH Terms:
| Smoking | Age Factors | Motivation |
| Risk Factors | Humans | Adult |
| Attitude | Adolescent | Cognition Disorders |
Smoking withdrawal dynamics: III. Correlates of withdrawal heterogeneity.
Authors: Piasecki TM, Jorenby DE, Smith SS, Fiore MC, Baker TB
Source: Exp Clin Psychopharmacol, 2003 Nov;11(4), p. 276-85.
PMID: 14599261
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724-02 | NIDA NIH HHS - DA07580-03 |
MeSH Terms:
Smoking withdrawal dynamics: II. Improved tests of withdrawal-relapse relations.
Authors: Piasecki TM, Jorenby DE, Smith SS, Fiore MC, Baker TB
Source: J Abnorm Psychol, 2003 Feb;112(1), p. 14-27.
PMID: 12653410
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724-02 | NIDA NIH HHS - DA07580-03 |
MeSH Terms:
Smoking withdrawal dynamics: I. Abstinence distress in lapsers and abstainers.
Authors: Piasecki TM, Jorenby DE, Smith SS, Fiore MC, Baker TB
Source: J Abnorm Psychol, 2003 Feb;112(1), p. 3-13.
PMID: 12653409
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724-02 | NIDA NIH HHS - DA07580-03 |
MeSH Terms:
| Smoking | Administration, Cutaneous | Substance Withdrawal Syndrome |
| Double-Blind Method | Nicotine | Humans |
| Smoking Cessation | Recurrence |
How will we know a lapse when we see one? Comment on Leri and Stewart (2002).
Authors: Baker TB, Curtin JJ
Source: Exp Clin Psychopharmacol, 2002 Nov;10(4), p. 350-2; discussion 364-6.
PMID: 12498328
Related Citations
Grant Numbers:
| NCI NIH HHS - 1 P50 CA84724 |
MeSH Terms:
| Rats | Models, Animal | Animals |
| Extinction, Psychological | Reproducibility of Results | Motivation |
| Heroin Dependence | Heroin | Humans |
| Reinforcement (Psychology) | Conditioning, Operant |
Effective tobacco dependence treatment.
Authors: Fiore MC, Hatsukami DK, Baker TB
Source: JAMA, 2002 Oct 9;288(14), p. 1768-71.
PMID: 12365962
Related Citations
Grant Numbers:
| NCI NIH HHS - 1 P50 CA84724 | NIDA NIH HHS - 1 P50 DA1333 |
MeSH Terms:
| United States | Cost of Illness | Tobacco Use Disorder |
| Humans | Cost-Benefit Analysis | Smoking Cessation |
| Practice Guidelines as Topic | Patient Care Management |
Pharmacotherapy for treating tobacco dependence: what is the ideal duration of therapy?
Authors: Sims TH, Fiore MC
Source: CNS Drugs, 2002;16(10), p. 653-62.
PMID: 12269859
Related Citations
Grant Numbers:
| NCI NIH HHS - P50-CA84724 |
MeSH Terms:
| Drug Administration Schedule | Substance Withdrawal Syndrome | Nicotine |
| Tobacco Use Disorder | Nicotinic Agonists | Humans |
| Smoking Cessation | Bupropion | Clinical Trials as Topic |
| Time Factors |
Have we lost our way? The need for dynamic formulations of smoking relapse proneness.
Authors: Piasecki TM, Fiore MC, McCarthy DE, Baker TB
Source: Addiction, 2002 Sep;97(9), p. 1093-108.
PMID: 12199822
Related Citations
Grant Numbers:
| NCI NIH HHS - CA84724 |
MeSH Terms:
| Smoking | Administration, Cutaneous | Fatigue |
| Motivation | Nicotine | Risk Factors |
| Humans | Stress, Psychological | Smoking Cessation |
| Forecasting | Recurrence |
Predicting relapse back to smoking: contrasting affective and physical models of dependence.
Authors: Kenford SL, Smith SS, Wetter DW, Jorenby DE, Fiore MC, Baker TB
Source: J Consult Clin Psychol, 2002 Feb;70(1), p. 216-27.
PMID: 11860048
Related Citations
Grant Numbers:
| NIDA NIH HHS - R01-DA07580 | NCI NIH HHS - P50-CA84724 |
MeSH Terms:
| Prospective Studies | Tobacco Use Disorder | Humans |
| Smoking Cessation | Adult | Aged |
| Middle Aged | Affect | Recurrence |
| Male | Female |
