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Grant Details

Grant Number: 5R01CA078257-05 Interpret this number
Primary Investigator: Huff, Vicki
Organization: Ut Md Anderson Cancer Ctr
Project Title: Molecular Investigation of Familial Wilms Tumor
Fiscal Year: 2003
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Abstract

An abstract does not currently exist for this grant

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Publications

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.
Authors: Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Lécureuil C, Guillou F, Huff V
Source: Proc Natl Acad Sci U S A, 2006 Aug 8;103(32), p. 11987-92.
EPub date: 2006 Jul 28.
PMID: 16877546
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Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors.
Authors: Ruteshouser EC, Hendrickson BW, Colella S, Krahe R, Pinto L, Huff V
Source: Genes Chromosomes Cancer, 2005 Jun;43(2), p. 172-80.
PMID: 15761866
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The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome.
Authors: Gao F, Maiti S, Sun G, Ordonez NG, Udtha M, Deng JM, Behringer RR, Huff V
Source: Mol Cell Biol, 2004 Nov;24(22), p. 9899-910.
PMID: 15509792
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Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.
Authors: Royer-Pokora B, Beier M, Henzler M, Alam R, Schumacher V, Weirich A, Huff V
Source: Am J Med Genet A, 2004 Jun 15;127A(3), p. 249-57.
PMID: 15150775
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Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors.
Authors: Udtha M, Lee SJ, Alam R, Coombes K, Huff V
Source: Oncogene, 2003 Jun 12;22(24), p. 3821-6.
PMID: 12802290
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Myc target in myeloid cells-1, a novel c-Myc target, recapitulates multiple c-Myc phenotypes.
Authors: Yin X, Grove L, Rogulski K, Prochownik EV
Source: J Biol Chem, 2002 May 31;277(22), p. 19998-20010.
EPub date: 2002 Mar 21.
PMID: 11909865
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Absence of PPP2R1A mutations in Wilms tumor.
Authors: Ruteshouser EC, Ashworth LK, Huff V
Source: Oncogene, 2001 Apr 12;20(16), p. 2050-4.
PMID: 11360189
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Pulmonary dysplasia, Denys-Drash syndrome and Wilms tumor 1 gene mutation in twins.
Authors: Dharnidharka VR, Ruteshouser EC, Rosen S, Kozakewich H, Harris HW Jr, Herrin JT, Huff V
Source: Pediatr Nephrol, 2001 Mar;16(3), p. 227-31.
PMID: 11322369
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Frequent association of beta-catenin and WT1 mutations in Wilms tumors.
Authors: Maiti S, Alam R, Amos CI, Huff V
Source: Cancer Res, 2000 Nov 15;60(22), p. 6288-92.
PMID: 11103785
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