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Grant Details

Grant Number: 5R01CA077305-03 Interpret this number
Primary Investigator: John, Esther
Organization: Cancer Prevention Instit Of California
Project Title: Vitamin D Receptor Gene Polymorphism and Breast Cancer
Fiscal Year: 2001
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Abstract

Experimental evidence and ecologic correlation studies support the hypothesis that vitamin D may reduce breast cancer risk. Yet this novel hypothesis is largely untested in human populations. An on-going population-based case-control study of breast cancer in Hispanic, African-American, and White Women will assess the associations with sunlight exposure and dietary vitamin D intake. On-going molecular research by one of the investigations of this applications suggests that polymorphisms of the vitamin D receptor (VDR) gene are related to the breast cancer risk. We therefore propose to expand the on-going case- control study in order to broaden our examination of the relation with vitamin D. In addition to the interview data being collected, we propose to obtain blood samples for a subset of study participants and to extend the case and control ascertainment by 10 months. Eligible cases will include women aged 35-79 and diagnosed with invasive breast cancer between May 1997 and February 1999. Cases will be identified through the cancer registries in the Greater San Francisco Bay area; controls will be selected from the general population through random-digit dialing. Professional interviewers will collect interview data, measure skin pigmentation, and obtain blood specimens through home visits. Blood specimens and risk factor data will be available for an estimated 640 cases (245 Hispanics, 225 Whites, and 170 African-Americans) and 960 controls (365 Hispanics, 340 Whites, and 255 African-Americans). We will assess (1) the association with two markers (poly-A and FOKI) of the VDR gene in Hispanics and Whites; (2) the association with the BsmI/poly-A haplotype in African-Americans; and (3) the possible modifying effect of VDR genotype on the association with sunlight exposure and dietary vitamin D intake. We will also bank DNA, buffy coat, and plasma for future molecular epidemiologic studies. Building upon the infrastructure of the on-going study, we have the opportunity to establish a valuable resource for more thoroughly assessing the relationship between vitamin D and breast cancer risk; for conducting future molecular epidemiologic research as new biomarkers and genes will be identified in the future; and for investigating gene-environment interactions in a multi-ethnic population. Since vitamin D exposure is potentially modifiable, the proposed research may have important implications for new approaches to breast cancer prevention.

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Publications

Impact of neighborhood and individual socioeconomic status on survival after breast cancer varies by race/ethnicity: the Neighborhood and Breast Cancer Study.
Authors: Shariff-Marco S, Yang J, John EM, Sangaramoorthy M, Hertz A, Koo J, Nelson DO, Schupp CW, Shema SJ, Cockburn M, Satariano WA, Yen IH, Ponce NA, Winkleby M, Keegan TH, Gomez SL
Source: Cancer Epidemiol Biomarkers Prev, 2014 May;23(5), p. 793-811.
EPub date: 2014 Mar 11.
PMID: 24618999
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The influence of genetic ancestry and ethnicity on breast cancer survival associated with genetic variation in the TGF-?-signaling pathway: The Breast Cancer Health Disparities Study.
Authors: Slattery ML, Lundgreen A, Stern MC, Hines L, Wolff RK, Giuliano AR, Baumgartner KB, John EM
Source: Cancer Causes Control, 2014 Mar;25(3), p. 293-307.
EPub date: 2013 Dec 12.
PMID: 24337772
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Genetic ancestry and risk of mortality among U.S. Latinas with breast cancer.
Authors: Fejerman L, Hu D, Huntsman S, John EM, Stern MC, Haiman CA, Pérez-Stable EJ, Ziv E
Source: Cancer Res, 2013 Dec 15;73(24), p. 7243-53.
EPub date: 2013 Oct 31.
PMID: 24177181
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Obesity and mortality after breast cancer by race/ethnicity: The California Breast Cancer Survivorship Consortium.
Authors: Kwan ML, John EM, Caan BJ, Lee VS, Bernstein L, Cheng I, Gomez SL, Henderson BE, Keegan TH, Kurian AW, Lu Y, Monroe KR, Roh JM, Shariff-Marco S, Sposto R, Vigen C, Wu AH
Source: Am J Epidemiol, 2014 Jan 1;179(1), p. 95-111.
EPub date: 2013 Oct 9.
PMID: 24107615
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Associations between genetic variants in the TGF-? signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women.
Authors: Boone SD, Baumgartner KB, Baumgartner RN, Connor AE, Pinkston CM, John EM, Hines LM, Stern MC, Giuliano AR, Torres-Mejia G, Brock GN, Groves FD, Kerber RA, Wolff RK, Slattery ML
Source: Breast Cancer Res Treat, 2013 Sep;141(2), p. 287-97.
EPub date: 2013 Sep 14.
PMID: 24036662
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Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study.
Authors: Slattery ML, John EM, Stern MC, Herrick J, Lundgreen A, Giuliano AR, Hines L, Baumgartner KB, Torres-Mejia G, Wolff RK
Source: Breast Cancer Res Treat, 2013 Aug;140(3), p. 587-601.
EPub date: 2013 Aug 3.
PMID: 23912956
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The California Breast Cancer Survivorship Consortium (CBCSC): prognostic factors associated with racial/ethnic differences in breast cancer survival.
Authors: Wu AH, Gomez SL, Vigen C, Kwan ML, Keegan TH, Lu Y, Shariff-Marco S, Monroe KR, Kurian AW, Cheng I, Caan BJ, Lee VS, Roh JM, Sullivan-Halley J, Henderson BE, Bernstein L, John EM, Sposto R
Source: Cancer Causes Control, 2013 Oct;24(10), p. 1821-36.
EPub date: 2013 Jul 18.
PMID: 23864487
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Angiogenesis genes, dietary oxidative balance and breast cancer risk and progression: the Breast Cancer Health Disparities Study.
Authors: Slattery ML, John EM, Torres-Mejia G, Lundgreen A, Lewinger JP, Stern MC, Hines L, Baumgartner KB, Giuliano AR, Wolff RK
Source: Int J Cancer, 2014 Feb 1;134(3), p. 629-44.
EPub date: 2013 Aug 9.
PMID: 23832257
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Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study.
Authors: Pellatt AJ, Wolff RK, Torres-Mejia G, John EM, Herrick JS, Lundgreen A, Baumgartner KB, Giuliano AR, Hines LM, Fejerman L, Cawthon R, Slattery ML
Source: Genes Chromosomes Cancer, 2013 Jul;52(7), p. 595-609.
EPub date: 2013 Apr 30.
PMID: 23629941
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Genome-wide association study of age at menarche in African-American women.
Authors: Demerath EW, Liu CT, Franceschini N, Chen G, Palmer JR, Smith EN, Chen CT, Ambrosone CB, Arnold AM, Bandera EV, Berenson GS, Bernstein L, Britton A, Cappola AR, Carlson CS, Chanock SJ, Chen W, Chen Z, Deming SL, Elks CE, Evans MK, Gajdos Z, Henderson BE, Hu JJ, Ingles S, John EM, Kerr KF, Kolonel LN, Le Marchand L, Lu X, Millikan RC, Musani SK, Nock NL, North K, Nyante S, Press MF, Rodriquez-Gil JL, Ruiz-Narvaez EA, Schork NJ, Srinivasan SR, Woods NF, Zheng W, Ziegler RG, Zonderman A, Heiss G, Gwen Windham B, Wellons M, Murray SS, Nalls M, Pastinen T, Rajkovic A, Hirschhorn J, Adrienne Cupples L, Kooperberg C, Murabito JM, Haiman CA
Source: Hum Mol Genet, 2013 Aug 15;22(16), p. 3329-46.
EPub date: 2013 Apr 17.
PMID: 23599027
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Authors: Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, NABEC Consortium, UKBEC Consortium, BioBank Japan Project, AGEN Consortium, Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA
Source: Nat Genet, 2013 Jun;45(6), p. 690-6.
EPub date: 2013 Apr 14.
PMID: 23583978
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Genetic ancestry modifies the association between genetic risk variants and breast cancer risk among Hispanic and non-Hispanic white women.
Authors: Fejerman L, Stern MC, Ziv E, John EM, Torres-Mejia G, Hines LM, Wolff R, Wang W, Baumgartner KB, Giuliano AR, Slattery ML
Source: Carcinogenesis, 2013 Aug;34(8), p. 1787-93.
EPub date: 2013 Apr 4.
PMID: 23563089
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A genome-wide scan for breast cancer risk haplotypes among African American women.
Authors: Song C, Chen GK, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, Deming SL, Rodriguez-Gil JL, Chanock SJ, Wan P, Sheng X, Pooler LC, Van Den Berg DJ, Le Marchand L, Kolonel LN, Henderson BE, Haiman CA, Stram DO
Source: PLoS One, 2013;8(2), p. e57298.
EPub date: 2013 Feb 28.
PMID: 23468962
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Genetic variation in bone morphogenetic proteins and breast cancer risk in hispanic and non-hispanic white women: The breast cancer health disparities study.
Authors: Slattery ML, John EM, Torres-Mejia G, Herrick JS, Giuliano AR, Baumgartner KB, Hines LM, Wolff RK
Source: Int J Cancer, 2013 Jun 15;132(12), p. 2928-39.
EPub date: 2012 Dec 13.
PMID: 23180569
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Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study.
Authors: Connor AE, Baumgartner RN, Baumgartner KB, Kerber RA, Pinkston C, John EM, Torres-Mejia G, Hines L, Giuliano A, Wolff RK, Slattery ML
Source: Breast Cancer Res Treat, 2012 Nov;136(2), p. 593-602.
EPub date: 2012 Oct 21.
PMID: 23085767
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A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Authors: Siddiq A, Couch FJ, Chen GK, Lindström S, Eccles D, Millikan RC, Michailidou K, Stram DO, Beckmann L, Rhie SK, Ambrosone CB, Aittomäki K, Amiano P, Apicella C, Australian Breast Cancer Tissue Bank Investigators, Baglietto L, Bandera EV, Beckmann MW, Berg CD, Bernstein L, Blomqvist C, Brauch H, Brinton L, Bui QM, Buring JE, Buys SS, Campa D, Carpenter JE, Chasman DI, Chang-Claude J, Chen C, Clavel-Chapelon F, Cox A, Cross SS, Czene K, Deming SL, Diasio RB, Diver WR, Dunning AM, Durcan L, Ekici AB, Fasching PA, Familial Breast Cancer Study, Feigelson HS, Fejerman L, Figueroa JD, Fletcher O, Flesch-Janys D, Gaudet MM, GENICA Consortium, Gerty SM, Rodriguez-Gil JL, Giles GG, van Gils CH, Godwin AK, Graham N, Greco D, Hall P, Hankinson SE, Hartmann A, Hein R, Heinz J, Hoover RN, Hopper JL, Hu JJ, Huntsman S, Ingles SA, Irwanto A, Isaacs C, Jacobs KB, John EM, Justenhoven C, Kaaks R, Kolonel LN, Coetzee GA, Lathrop M, Le Marchand L, Lee AM, Lee IM, Lesnick T, Lichtner P, Liu J, Lund E, Makalic E, Martin NG, McLean CA, Meijers-Heijboer H, Meindl A, Miron P, Monroe KR, Montgomery GW, Müller-Myhsok B, Nickels S, Nyante SJ, Olswold C, Overvad K, Palli D, Park DJ, Palmer JR, Pathak H, Peto J, Pharoah P, Rahman N, Rivadeneira F, Schmidt DF, Schmutzler RK, Slager S, Southey MC, Stevens KN, Sinn HP, Press MF, Ross E, Riboli E, Ridker PM, Schumacher FR, Severi G, Dos Santos Silva I, Stone J, Sund M, Tapper WJ, Thun MJ, Travis RC, Turnbull C, Uitterlinden AG, Waisfisz Q, Wang X, Wang Z, Weaver J, Schulz-Wendtland R, Wilkens LR, Van Den Berg D, Zheng W, Ziegler RG, Ziv E, Nevanlinna H, Easton DF, Hunter DJ, Henderson BE, Chanock SJ, Garcia-Closas M, Kraft P, Haiman CA, Vachon CM
Source: Hum Mol Genet, 2012 Dec 15;21(24), p. 5373-84.
EPub date: 2012 Sep 13.
PMID: 22976474
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A genome-wide association study of breast cancer in women of African ancestry.
Authors: Chen F, Chen GK, Stram DO, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Palmer JR, Hu JJ, Rebbeck TR, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, Ruiz-Narvaez EA, Deming SL, Rodriguez-Gil JL, Demichele A, Chanock SJ, Blot W, Signorello L, Cai Q, Li G, Long J, Huo D, Zheng Y, Cox NJ, Olopade OI, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Simon MS, Hennis A, Nemesure B, Wu SY, Leske MC, Ambs S, Hutter CM, Young A, Kooperberg C, Peters U, Rhie SK, Wan P, Sheng X, Pooler LC, Van Den Berg DJ, Le Marchand L, Kolonel LN, Henderson BE, Haiman CA
Source: Hum Genet, 2013 Jan;132(1), p. 39-48.
EPub date: 2012 Aug 25.
PMID: 22923054
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Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population.
Authors: Slattery ML, John EM, Torres-Mejia G, Lundgreen A, Herrick JS, Baumgartner KB, Hines LM, Stern MC, Wolff RK
Source: Carcinogenesis, 2012 Aug;33(8), p. 1512-21.
EPub date: 2012 May 4.
PMID: 22562547
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Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas.
Authors: Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E
Source: Hum Mol Genet, 2012 Apr 15;21(8), p. 1907-17.
EPub date: 2012 Jan 6.
PMID: 22228098
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Early-life factors and breast cancer risk in Hispanic women: the role of adolescent body size.
Authors: Sangaramoorthy M, Phipps AI, Horn-Ross PL, Koo J, John EM
Source: Cancer Epidemiol Biomarkers Prev, 2011 Dec;20(12), p. 2572-82.
EPub date: 2011 Nov 4.
PMID: 22056503
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Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.
Authors: Chen F, Chen GK, Millikan RC, John EM, Ambrosone CB, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Deming SL, Bandera EV, Nyante S, Palmer JR, Rebbeck TR, Ingles SA, Press MF, Rodriguez-Gil JL, Chanock SJ, Le Marchand L, Kolonel LN, Henderson BE, Stram DO, Haiman CA
Source: Hum Mol Genet, 2011 Nov 15;20(22), p. 4491-503.
EPub date: 2011 Aug 18.
PMID: 21852243
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The landscape of recombination in African Americans.
Authors: Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA Jr, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR
Source: Nature, 2011 Jul 20;476(7359), p. 170-5.
EPub date: 2011 Jul 20.
PMID: 21775986
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Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.
Authors: Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, Musani SK, Divers J, Mychaleckyj J, Li M, Papanicolaou GJ, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Ingles SA, Press MF, Chanock SJ, Deming SL, Rodriguez-Gil JL, Palmer CD, Buxbaum S, Ekunwe L, Hirschhorn JN, Henderson BE, Myers S, Haiman CA, Reich D, Patterson N, Wilson JG, Price AL
Source: PLoS Genet, 2011 Apr;7(4), p. e1001371.
EPub date: 2011 Apr 21.
PMID: 21541012
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Germline mutations in PALB2 in African-American breast cancer cases.
Authors: Ding YC, Steele L, Chu LH, Kelley K, Davis H, John EM, Tomlinson GE, Neuhausen SL
Source: Breast Cancer Res Treat, 2011 Feb;126(1), p. 227-30.
EPub date: 2010 Nov 27.
PMID: 21113654
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Adult body size, hormone receptor status, and premenopausal breast cancer risk in a multiethnic population: the San Francisco Bay Area breast cancer study.
Authors: John EM, Sangaramoorthy M, Phipps AI, Koo J, Horn-Ross PL
Source: Am J Epidemiol, 2011 Jan 15;173(2), p. 201-16.
EPub date: 2010 Nov 17.
PMID: 21084558
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The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data.
Authors: Chen GK, Millikan RC, John EM, Ambrosone CB, Bernstein L, Zheng W, Hu JJ, Chanock SJ, Ziegler RG, Bandera EV, Henderson BE, Haiman CA, Stram DO
Source: PLoS Genet, 2010 Sep 2;6(9), p. e1001096.
EPub date: 2010 Sep 2.
PMID: 20824062
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European ancestry is positively associated with breast cancer risk in Mexican women.
Authors: Fejerman L, Romieu I, John EM, Lazcano-Ponce E, Huntsman S, Beckman KB, Pérez-Stable EJ, González Burchard E, Ziv E, Torres-Mejía G
Source: Cancer Epidemiol Biomarkers Prev, 2010 Apr;19(4), p. 1074-82.
EPub date: 2010 Mar 23.
PMID: 20332279
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An admixture scan in 1,484 African American women with breast cancer.
Authors: Fejerman L, Haiman CA, Reich D, Tandon A, Deo RC, John EM, Ingles SA, Ambrosone CB, Bovbjerg DH, Jandorf LH, Davis W, Ciupak G, Whittemore AS, Press MF, Ursin G, Bernstein L, Huntsman S, Henderson BE, Ziv E, Freedman ML
Source: Cancer Epidemiol Biomarkers Prev, 2009 Nov;18(11), p. 3110-7.
EPub date: 2009 Oct 20.
PMID: 19843668
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Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.
Authors: Cheng CY, Kao WH, Patterson N, Tandon A, Haiman CA, Harris TB, Xing C, John EM, Ambrosone CB, Brancati FL, Coresh J, Press MF, Parekh RS, Klag MJ, Meoni LA, Hsueh WC, Fejerman L, Pawlikowska L, Freedman ML, Jandorf LH, Bandera EV, Ciupak GL, Nalls MA, Akylbekova EL, Orwoll ES, Leak TS, Miljkovic I, Li R, Ursin G, Bernstein L, Ardlie K, Taylor HA, Boerwinckle E, Zmuda JM, Henderson BE, Wilson JG, Reich D
Source: PLoS Genet, 2009 May;5(5), p. e1000490.
EPub date: 2009 May 22.
PMID: 19461885
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Genetic ancestry and risk of breast cancer among U.S. Latinas.
Authors: Fejerman L, John EM, Huntsman S, Beckman K, Choudhry S, Perez-Stable E, Burchard EG, Ziv E
Source: Cancer Res, 2008 Dec 1;68(23), p. 9723-8.
PMID: 19047150
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5-lipoxygenase and 5-lipoxygenase-activating protein gene polymorphisms, dietary linoleic acid, and risk for breast cancer.
Authors: Wang J, John EM, Ingles SA
Source: Cancer Epidemiol Biomarkers Prev, 2008 Oct;17(10), p. 2748-54.
PMID: 18843019
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Dietary fat, cooking fat, and breast cancer risk in a multiethnic population.
Authors: Wang J, John EM, Horn-Ross PL, Ingles SA
Source: Nutr Cancer, 2008;60(4), p. 492-504.
PMID: 18584483
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Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women.
Authors: Setiawan VW, Chu LH, John EM, Ding YC, Ingles SA, Bernstein L, Press MF, Ursin G, Haiman CA, Neuhausen SL
Source: Cancer Genet Cytogenet, 2008 Feb;181(1), p. 16-9.
PMID: 18262047
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Genetic variation in IGFBP2 and IGFBP5 is associated with breast cancer in populations of African descent.
Authors: Garner CP, Ding YC, John EM, Ingles SA, Olopade OI, Huo D, Adebamowo C, Ogundiran T, Neuhausen SL
Source: Hum Genet, 2008 Apr;123(3), p. 247-55.
EPub date: 2008 Jan 22.
PMID: 18210156
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Sun exposure, vitamin D receptor gene polymorphisms, and breast cancer risk in a multiethnic population.
Authors: John EM, Schwartz GG, Koo J, Wang W, Ingles SA
Source: Am J Epidemiol, 2007 Dec 15;166(12), p. 1409-19.
EPub date: 2007 Oct 12.
PMID: 17934201
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The role of self-defined race/ethnicity in population structure control.
Authors: Liu XQ, Paterson AD, John EM, Knight JA
Source: Ann Hum Genet, 2006 Jul;70(Pt 4), p. 496-505.
PMID: 16759181
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